1,8-Dihydroxy-3,6-dimethylanthracene-9,10-dione

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 1,8-Dihydroxy-3,6-dimethylanthracene-9,10-dione
• 化学式: C₁₆H₁₂O₄
• 分子量: 268.26
• InChiKey: PKUBGLYEOAJPEG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  20
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Oxidative Färbemittel
  申请人：Henkel AG & Co. KGaA

  公开号：EP2301520B1

  公开（公告）日：2017-03-08
• Anthraquinones and Analogs from Rhuem palmatum for Treatment of Estrogen Receptor Beta-Mediated Conditions
  申请人：Cohen Isaac

  公开号：US20090312437A1

  公开（公告）日：2009-12-17

  Compositions derived from Rheum palmatum are provided. Also provided are methods of using said extracts to induce apoptosis in specific cells, especially in a human. Provided as well are uses of the extracts of Rheum palmatum for the preparation of a medicament for the selective induction of apoptosis
• ANTHRACENEDIONE COMPOUNDS
  申请人：Chien Du-Shieng

  公开号：US20100256239A1

  公开（公告）日：2010-10-07

  This invention relates compositions containing compounds of formula (I) below: Each of R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , and R 8 is defined in the specification.
• USE OF 9, 10-ANTHRAQUINONE COMPOUNDS
  申请人：Wang Shuguang

  公开号：US20110224414A1

  公开（公告）日：2011-09-15

  Use of 9,10-anthraquinone compounds of formula (I) or pharmaceutical salts thereof or plant extracts containing said compounds in the preparation of anti-HCV medicaments is disclosed, in which Y 1 are Y 2 are independently hydrogen, hydroxyl or groups of formula (II); and R 1 , R 2 , R 3 , R 4 , R 5 and R 6 are independently hydrogen, hydroxyl, carboxyl, cyano group, nitro group, groups of formula (III) or groups selected from those substituted or unsubstituted groups: amino, C 1 -C 6 aliphatic hydrocarbon, C 3 -C 7 cyclic aliphatic hydrocarbon, C 1 -C 6 alkoxy, C 2 -C 7 carbalkoxy, C 1 -C 4 acyloxy, C 6 -C 20 aryl, or 5 to 7 members heterocyclic or benzoheterocyclic thereof; or R 5 and R 6 form the group of formula (IV). The compounds of present invention are cheap, safe and effective, because that they mostly conic from traditional Chinese medicines and have better anti-HCV effects and lighter side effects.
• SMALL-MOLECULE INHIBITORS OF DENGUE AND WEST NILE VIRUS PROTEASES
  申请人：Watowich Stanley J.

  公开号：US20130035284A1

  公开（公告）日：2013-02-07

  The present invention concerns methods and compositions involving small molecule inhibitors for the treatment or prophylaxis of flavivirus infection, such as dengue virus and West Nile virus.