2-hydroxy-3-(3-oxo-1-phenylbutyl)chromen-4-one

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 高异黄酮
• 英文名称: 2-hydroxy-3-(3-oxo-1-phenylbutyl)chromen-4-one
• 化学式: C₁₉H₁₆O₄
• 分子量: 308.3
• InChiKey: QTXVAVXCBMYBJW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.16
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Separation And Manipulation Of A Chiral Object
  申请人：Kibar Osman

  公开号：US20080262240A1

  公开（公告）日：2008-10-23

  Among other things, to cause directional motion of chiral objects in a mixture in a chamber, a field is rotated relative, to a chamber to cause rotation of the chiral objects. The rotation of the objects causes them to move directionally based on their chirality.

  在混合物室中，为了使手性物体产生定向运动，需要旋转一个场，相对于室内旋转手性物体。物体的旋转会根据它们的手性定向移动。
• Therapeutic approaches for treating Alzheimer disease and related disorders through a modulation of synapse function
  申请人：Pharnext

  公开号：US10350195B2

  公开（公告）日：2019-07-16

  Compositions and methods for the treatment of Alzheimer's disease and related disorders. More particularly, disclosed are combined therapies that modulate synapse function for treating the disease.

  治疗阿尔茨海默病及相关疾病的组合物和方法。更具体地说，公开了用于治疗该疾病的调节突触功能的组合疗法。
• Methods and compositions for treating urea cycle disorders
  申请人：Camp4 Therapeutics Corporation

  公开号：US11266655B2

  公开（公告）日：2022-03-08

  Provided are methods and compositions for the treating a patient with a urea cycle disorder. Methods and compositions are also provided for modulating genes encoding enzymes that participate in the urea cycle by altering gene signaling networks.

  本文提供了治疗尿素循环障碍患者的方法和组合物。还提供了通过改变基因信号网络来调节编码参与尿素循环的酶的基因的方法和组合物。
• Bait composition
  申请人：Scimetrics Limited Corp.

  公开号：US11382325B2

  公开（公告）日：2022-07-12

  Disclosed herein are embodiments of a feral hog control system including bait comprising a carrier material and an amount of warfarin, wherein the amount of warfarin is not greater than about 0.01% by weight of the bait. Further disclosed herein are embodiments of a selective access device for permitting selective access to the bait when the bait is disposed within a feeder.

  本文公开了一种野猪控制系统的实施方案，该系统包括由载体材料和一定量的华法林组成的饵料，其中华法林量不大于饵料重量的约 0.01%。本文进一步公开了一种选择性取用装置的实施例，当饵料放置在喂食器中时，该装置允许选择性取用饵料。
• NEW THERAPEUTIC APPROACHES FOR TREATING ALZHEIMER DISEASE AND RELATED DISORDERS THROUGH A MODULATION OF ANGIOGENESIS
  申请人：Pharnext

  公开号：EP2282778B1

  公开（公告）日：2017-03-08