N-acetyl-3,4-methylenedioxymethcathinone | 1227293-15-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并间二氧杂环戊烯类
• 英文名称: N-acetyl-3,4-methylenedioxymethcathinone
• 英文别名: N-[1-(1,3-benzodioxol-5-yl)-1-oxopropan-2-yl]-N-methylacetamide
• CAS: 1227293-15-3
• 化学式: C₁₃H₁₅NO₄
• 分子量: 249.26
• InChiKey: SFBOFEWMUYVYDF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  55.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  乙酰氯 、 2-甲基氨基-1-(3,4-亚甲二氧苯基)-1-丙酮盐酸盐 在 N,N-二异丙基乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 N-acetyl-3,4-methylenedioxymethcathinone
  参考文献：
  名称：

  PHENETHYLAMINES AND CATHINONES PRECURSORS

  摘要：

  The subject matter disclosed generally relates to phenethylamines or cathinones covalently bound to a chemical moiety in a prodrug form. The presently described technology allows slow/sustained/controlled delivery of the parent phenethylamines or cathinones into the blood system in a manner that increase the duration of therapeutic efficacy, ease of application, patient compliance and/or a combination of these characteristics when administered, in particular, orally. Additionally, the described technology allows gradual release of the parent phenethylamines or cathinones over an extended period of time thereby eliminating spiking of drug levels which lessen cardiovascular stress, addiction/abuse potential and/or other common stimulant side effects associated with psychoactive compounds.

  公开号：

  WO2024039599A1