Rearrangement of Benzylic Trichloroacetimidates to Benzylic Trichloroacetamides
作者:Arijit A. Adhikari、Tamie Suzuki、Reesheda T. Gilbert、Matthew R. Linaburg、John D. Chisholm
DOI:10.1021/acs.joc.7b00245
日期:2017.4.7
The rearrangement of allylic trichloroacetimidates is a well-known transformation, but the corresponding rearrangement of benzylic trichloroacetimidates has not been explored as a method for the synthesis of benzylic amines. Conditions that provide the trichloroacetamide product from a benzylic trichloroacetimidate in high yield have been developed. Methods were also investigated to transform the trichloroacetamide