One-Step Conversion of Acetophenones to α-Haloacetophenone Dimethyl Acetals Using DCDMH/DBDMH and Molecular Sieve in Methanol
摘要:
Using DCDMH/DBDMH as N-halo reagent, piperidine as catalyst, and 4-A molecular sieve as water-removing agent, alpha-haloacetophenone dimethyl acetals were directly obtained from the solvent of methanol. As to the substrates with electron-withdrawing groups, the conversions were 80-100%.
A One-Pot Method Synthesis of α-Chloroketone Dimethyl Acetals
作者:Zhou Zhong-shi、Li Li、He Xue-han
DOI:10.3184/174751913x13794472538108
日期:2013.10
been developed for the direct preparation of α-chloroketone dimethyl acetals from ketones using ammonium chloride as the source of chlorine and potassium monoperoxysulfate as the oxidant in the presence of trimethyl orthoformate in methanol at room temperature. Ketones which have electron-withdrawing groups on the aryl rings gave the corresponding α-chloroketone dimethyl acetals in moderate to good yields
One-Step Conversion of Acetophenones to <font>α</font>-Haloacetophenone Dimethyl Acetals Using DCDMH/DBDMH and Molecular Sieve in Methanol
作者:Bin Zhou、Zizhan Chen、Zubiao Zheng、Bingbing Han、Xinzhuo Zou
DOI:10.1080/00397911.2010.540696
日期:2012.5.15
Using DCDMH/DBDMH as N-halo reagent, piperidine as catalyst, and 4-A molecular sieve as water-removing agent, alpha-haloacetophenone dimethyl acetals were directly obtained from the solvent of methanol. As to the substrates with electron-withdrawing groups, the conversions were 80-100%.