Mulberrofuran T | 125882-66-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 2-芳基苯并呋喃类黄酮
• 英文名称: Mulberrofuran T
• 英文别名: [2-[2,6-dihydroxy-4-[6-hydroxy-7-(3-methylbut-2-enyl)-1-benzofuran-2-yl]phenyl]-6-(2,4-dihydroxyphenyl)-4-methylcyclohex-3-en-1-yl]-[2,4-dihydroxy-3-(3-methylbut-2-enyl)phenyl]methanone
• CAS: 125882-66-8
• 化学式: C₄₄H₄₄O₉
• 分子量: 716.8
• InChiKey: XMXZFZDVDCIFKB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.8
• 重原子数：
  53
• 可旋转键数：
  9
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  172
• 氢给体数：
  7
• 氢受体数：
  9

文献信息

• Compositions and methods for joint health
  申请人：Unigen, Inc.

  公开号：US11123393B2

  公开（公告）日：2021-09-21

  The present disclosure provides mixtures of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both capable of modulating joint inflammation, joint pain, joint stiffness, cartilage degradation, or improving mobility, range of motion, flexibility, joint physical function, or any combination thereof. Such a mixture of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both can optionally be used in combination with other joint management agents, such as non-steroidal anti-inflammatory agents/analgesics, COX/LOX inhibiting agents, glucosamine compounds, neuropathic pain relief agents, or the like.

  本公开提供了前炔类黄酮、二苯乙烯类化合物或二者与黄烷或姜黄素或二者的混合物，能够调节关节炎症、关节疼痛、关节僵硬、软骨退化，或改善活动能力、活动范围、柔韧性、关节物理功能或其任意组合。这种前炔类黄酮、二苯乙烯类化合物或二者与黄烷或姜黄素或二者的混合物可以选择性地与其他关节调理剂结合使用，如非甾体抗炎剂/镇痛剂、COX/LOX 抑制剂、氨基葡萄糖化合物、神经性疼痛缓解剂等。
• Root extracts from plants of the Morus genus and uses of same
  申请人：PLANT ADVANCED TECHNOLOGIES PAT

  公开号：US11311593B2

  公开（公告）日：2022-04-26

  Disclosed is a root extract from plants of the Morus genus (in particular Morus albaet, Morus nigra) that is rich in prenylated polyphenols chosen from: moracenin A, moracenin B, kuwanon C, wittiorumin F and mulberrofuran T, a method for preparing such an extract and a cosmetic composition and a pharmaceutical or nutraceutical composition, the compositions including, as the active ingredient, at least one root extract from plants of the Morus genus according to the invention.

  本发明公开了一种从桑科植物（特别是白桑树和黑桑树）中提取的根提取物，该提取物富含前炔化多酚，这些前炔化多酚选自：桑苷 A、桑苷 B、桑苷 C、桑苷 F 和桑白呋喃 T；本发明还公开了一种制备这种提取物的方法，以及一种化妆品组合物和一种药物或营养品组合物，这些组合物包括至少一种根据本发明提取的桑科植物根提取物作为活性成分。
• COMPOSITIONS AND METHODS FOR JOINT HEALTH
  申请人：Unigen, Inc.

  公开号：US20150072953A1

  公开（公告）日：2015-03-12

  The present disclosure provides mixtures of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both capable of modulating joint inflammation, joint pain, joint stiffness, cartilage degradation, or improving mobility, range of motion, flexibility, joint physical function, or any combination thereof. Such a mixture of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both can optionally be used in combination with other joint management agents, such as non-steroidal anti-inflammatory agents/analgesics, COX/LOX inhibiting agents, glucosamine compounds, neuropathic pain relief agents, or the like.
• COMPOSITIONS AND METHODS FOR MANAGING OR IMPROVING BONE DISORDERS, CARTILAGE DISORDERS, OR BOTH
  申请人：Unigen, Inc.

  公开号：US20160045559A1

  公开（公告）日：2016-02-18

  The present disclosure provides mixtures of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both capable of useful for promoting, managing or improving bone health, cartilage health or both, or for preventing or treating a bone disorder, cartilage disorder or both. Such a mixture of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both can optionally be used in combination with other bone and cartilage management agents, such as calcium, magnesium, zinc, boron, vitamin D, vitamin K, glucosamine and/or chondroitin compounds, non-steroidal anti-inflammatory agents/analgesics, COX/LOX inhibiting agents, neuropathic pain relief agents, or the like.
• Compositions and Methods for Joint Health
  申请人：Unigen, Inc.

  公开号：US20160067296A1

  公开（公告）日：2016-03-10

  The present disclosure provides mixtures of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both capable of modulating joint inflammation, joint pain, joint stiffness, cartilage degradation, or improving mobility, range of motion, flexibility, joint physical function, or any combination thereof. Such a mixture of prenylated flavonoids, stilbenes, or both with flavans or curcuminoids or both can optionally be used in combination with other joint management agents, such as non-steroidal anti-inflammatory agents/analgesics, COX/LOX inhibiting agents, glucosamine compounds, neuropathic pain relief agents, or the like.