6-Methyl-[1,2,5]oxadiazolo[3,4-c]pyridine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 6-Methyl-[1,2,5]oxadiazolo[3,4-c]pyridine
• 英文别名: 6-methyl-[1,2,5]oxadiazolo[3,4-c]pyridine
• 化学式: C₆H₅N₃O
• 分子量: 135.12
• InChiKey: YQFKROZYTRVSSK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  51.8
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] HERBICIDAL COMPOUNDS<br/>[FR] COMPOSÉS HERBICIDES
  申请人：SYNGENTA CROP PROTECTION AG

  公开号：WO2021058595A1

  公开（公告）日：2021-04-01

  Compounds of the formula (I) wherein the substituents are as defined in claim 1, useful as a pesticides, especially as herbicides.

  式(I)的化合物，其中取代基如权利要求1所定义，作为杀虫剂特别是除草剂时有用。
• PRMT5 INHIBITORS AND USES THEREOF
  申请人：Epizyme, Inc.

  公开号：US20150191432A1

  公开（公告）日：2015-07-09

  Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.

  本文描述了公式（I）的化合物，其药学上可接受的盐和制药组合物。本发明的化合物对于抑制PRMT5活性是有用的。还描述了使用这些化合物治疗PRMT5介导的疾病的方法。
• PRMT5 INHIBITORS CONTAINING A DIHYDRO- OR TETRAHYDROISOQUINOLINE AND USES THEREOF
  申请人：EPIZYME, INC.

  公开号：US20150344433A1

  公开（公告）日：2015-12-03

  Described herein are compounds of Formula (A), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.

  本文描述了公式（A）的化合物，其药学上可接受的盐和药物组合物。本发明的化合物可用于抑制PRMT5活性。还描述了使用这些化合物治疗PRMT5介导的疾病的方法。
• INK COMPOSITION AND PHOTOELECTRIC CONVERSION DEVICE PRODUCED USING THE SAME
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20170237012A1

  公开（公告）日：2017-08-17

  An ink composition containing a P-type semiconductor material, an N-type semiconductor material and two or more solvents including a first solvent and a second solvent, wherein the total amount of the first solvent and the second solvent is 70% by weight or more with respect to 100% by weight of all the solvents contained in the ink composition; the boiling point of the first solvent is lower than the boiling point of the second solvent; the boiling point of the first solvent is 120° C. or more and 400° C. or less; and the hydrogen bond Hansen solubility parameter H1 (MPa 0.5 ) of the first solvent and the hydrogen bond Hansen solubility parameter H2 (MPa 0.5 ) of the second solvent are in the relation of 0.5≦(H2−H1)≦5.0.
• TETRAHYDRO- AND DIHYDRO-ISOQUINOLINE PRMT5 INHIBITORS AND USES THEREOF
  申请人：Epizyme, Inc.

  公开号：US20170334861A1

  公开（公告）日：2017-11-23

  Described herein are compounds of Formula (A), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.