N-[2-(RS)-amino-3-methylbutyl] 4-methylbenzamide hydrochloride | 851524-87-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[2-(RS)-amino-3-methylbutyl] 4-methylbenzamide hydrochloride
• 英文别名: N-[2-(RS)-amino-3-methylbutyl]-4-methylbenzamide hydrochloride；N-(4-methylbenzoyl)-3-methyl-1,2-butanediamine hydrochloride；N-(2-amino-3-methylbutyl)-4-methylbenzamide;hydrochloride
• CAS: 851524-87-3
• 化学式: C₁₃H₂₀N₂O*ClH
• 分子量: 256.776
• InChiKey: TZKHCEQYCUNVJN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.13
• 重原子数：
  17
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  55.1
• 氢给体数：
  3
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  N-[2-(RS)-amino-3-methylbutyl] 4-methylbenzamide hydrochloride 、 氯甲酸氯甲酯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 4.0h， 生成 N-(chloromethyloxycarbonyl)-N'-(4-methylbenzoyl)-3-methyl-1,2-butanediamine
  参考文献：
  名称：

  EP1681285

  摘要：

  公开号：

文献信息

• PESTICIDAL COMPOSITION
  申请人：Mitsui Chemicals, Inc.

  公开号：EP1872658A1

  公开（公告）日：2008-01-02

  An object of the present invention is to provide a composition for preventing harmful organisms exerting an excellent control effect against plant diseases and/or insecticidal effect. Disclosed is a composition for preventing harmful organisms comprising a diamine derivative represented by the formula (1), and one or more compounds selected from the group consisting of other fungicides, insecticides and acaricides as active ingredients, wherein, in the formula, R1 represents a hydrocarbon having 1 to 6 carbon atoms which is substituted with halogen or the like; R2 and R7 each independently represent a hydrogen atom, a hydrocarbon having 1 to 6 carbon atoms or the like; R3 and R4 each independently represent a hydrogen atom, a hydrocarbon having 1 to 6 carbon atoms which may be substituted or the like, or R3 and R4 represent a cycloalkyl group having 3 to 6 carbon atoms containing a carbon atom bonded thereto; R5 and R6 each independently represent a hydrogen atom, a hydrocarbon group having 1 to 6 carbon atoms or the like; and R8 represents an arylalkyl group which may be substituted, an aryl group which may be substituted or a heteroaryl group which may be substituted.

  本发明的目的是提供一种用于防止有害生物对植物病害和/或杀虫效果具有优异控制效果的组合物。公开了一种用于防止有害生物的组合物，包括由式（1）表示的二胺衍生物，以及作为活性成分的从其他杀菌剂、杀虫剂和螨虫剂组成的化合物中选择的一种或多种化合物， 其中，在该式中，R1代表具有1至6个碳原子的烃，其被卤素或类似物取代；R2和R7各自独立地代表氢原子，具有1至6个碳原子的烃或类似物；R3和R4各自独立地代表氢原子，具有1至6个碳原子的烃，可能被取代或类似物，或者R3和R4代表含有与之相结合的碳原子的3至6个碳原子的环烷基；R5和R6各自独立地代表氢原子，具有1至6个碳原子的烃基或类似物；R8代表可能被取代的芳基烷基，可能被取代的芳基或可能被取代的杂芳基。
• Composition For Preventing Harmful Organisms
  申请人：Tomura Naofumi

  公开号：US20090023667A1

  公开（公告）日：2009-01-22

  An object of the present invention is to provide a composition for preventing harmful organisms exerting an excellent control effect against plant diseases and/or insecticidal effect. Disclosed is a composition for preventing harmful organisms comprising a diamine derivative represented by the formula (1), and one or more compounds selected from the group consisting of other fungicides, insecticides and acaricides as active ingredients, wherein, in the formula, R1 represents a hydrocarbon having 1 to 6 carbon atoms which is substituted with halogen or the like; R2 and R7 each independently represent a hydrogen atom, a hydrocarbon having 1 to 6 carbon atoms or the like; R3 and R4 each independently represent a hydrogen atom, a hydrocarbon having 1 to 6 carbon atoms which may be substituted or the like, or R3 and R4 represent a cycloalkyl group having 3 to 6 carbon atoms containing a carbon atom bonded thereto; R5 and R6 each independently represent a hydrogen atom, a hydrocarbon group having 1 to 6 carbon atoms or the like; and R8 represents an arylalkyl group which may be substituted, an aryl group which may be substituted or a heteroaryl group which may be substituted.

  本发明的目的是提供一种防止有害生物的组合物，该组合物对植物病害和/或杀虫效果具有出色的控制效果。所披露的防止有害生物的组合物包括由式（1）表示的二胺衍生物和选自其他杀菌剂、杀虫剂和杀螨剂的一个或多个化合物作为活性成分。其中，式中，R1表示具有1到6个碳原子的烃基，其被卤素或类似物取代; R2和R7各自独立地表示氢原子，具有1到6个碳原子的烃基或类似物; R3和R4各自独立地表示氢原子，具有1到6个碳原子的烃基，其可能被取代或类似物，或者R3和R4表示含有3到6个碳原子的环烷基，其中含有一个碳原子与之相连; R5和R6各自独立地表示氢原子，具有1到6个碳原子的烃基或类似物; R8表示可能被取代的芳基烷基，可能被取代的芳基或可能被取代的杂环芳基。
• Diamine Derivative, Process of Preparation Thereof, and Fungicide Comprising Diamine Derivative as an Active Ingredient
  申请人：Kakimoto Takeshi

  公开号：US20070244153A1

  公开（公告）日：2007-10-18

  It is an object of the invention to provide a novel fungicide which exhibits a wide controlling spectrum against pathogens of various crops, and solves the toleration problem. The diamine derivative represented by the formula (1) and a process for preparation of the same, fungicides comprising the same as an active ingredient are disclosed: [wherein R1 is substituents such as an alkyl group having 1 to 6 carbon atoms and the like, R2 and R5 are each independently substituents such as hydrogen atom, an alkyl group having 1 to 6 carbon atoms and the like, R3 and R4 are each independently substituents such as hydrogen atom, an alkyl group having 1 to 6 carbon atoms and the like, or R3 and R4 may be bonded to each other to form a hydrocarbon ring having 3 to 6 carbon atoms, R6, R7, R8 and R9 are each independently substituents such as hydrogen atom, an alkyl group having 1 to 6 carbon atoms and the like, R10 is a substituent such as hydrogen atom, an alkyl group having 1 to 6 carbon atoms and the like, A is an oxygen atom or a sulfur atom, and Q is an aryl group or a heterocycle].

  本发明的目的是提供一种新型杀菌剂，该杀菌剂对各种作物的病原体具有广泛的控制谱，并解决了容忍问题。本发明公开了由式（1）表示的二胺衍生物及其制备方法，以及包含其作为活性成分的杀菌剂：[其中，R1是取代基，例如具有1到6个碳原子的烷基等，R2和R5各自独立地是氢原子、具有1到6个碳原子的烷基等取代基，R3和R4各自独立地是氢原子、具有1到6个碳原子的烷基等取代基，或者R3和R4可以结合在一起形成具有3到6个碳原子的碳氢环，R6、R7、R8和R9各自独立地是氢原子、具有1到6个碳原子的烷基等取代基，R10是氢原子、具有1到6个碳原子的烷基等取代基，A是氧原子或硫原子，Q是芳基或杂环]。
• Diamine derivatives, process for producing the same, and plant disease control agents containing the same as active ingredients
  申请人：Ebihara Koichi

  公开号：US20070049635A1

  公开（公告）日：2007-03-01

  It is an object of the present invention to provide a diamine derivative, a process for producing the same, and a plant disease control agent containing the above-described compound as an active ingredient. According to the present invention, a diamine derivative represented by Formula (1), a process for producing the same, and a plant disease control agent containing the above-described compound as an active ingredient are provided. [In Formula, R1 represents, for example, a halogenated hydrocarbon having the carbon number of 1 to 6; R2 and R7 independently represent, for example, a hydrogen atom or a hydrocarbon having the carbon number of 1 to 6; R3 and R4 independently represent, for example, a hydrogen atom or a hydrocarbon which has the carbon number of 1 to 6 and which may be substituted, or represent a cycloalkyl group having the carbon number of 3 to 6 including a carbon atom bonding to R3 and R4; R5 and R6 independently represent, for example, a hydrogen atom or a hydrocarbon group having the carbon number of 1 to 6; and R8 represents an arylalkyl group which may be substituted, an aryl group which may be substituted, or a heteroaryl group which may be substituted.]

  本发明的目的是提供一种二胺衍生物、其制备方法以及含有上述化合物作为活性成分的植物病害控制剂。根据本发明，提供了一种由式（1）表示的二胺衍生物，其制备方法以及含有上述化合物作为活性成分的植物病害控制剂。[在式中，R1代表例如碳数为1至6的卤代烃化合物；R2和R7独立地代表例如氢原子或碳数为1至6的碳氢化合物；R3和R4独立地代表例如氢原子或碳数为1至6的可取代碳氢化合物，或代表包括与R3和R4结合的碳原子的碳数为3至6的环烷基；R5和R6独立地代表例如氢原子或碳数为1至6的碳氢基团；R8代表可取代的芳基烷基团、可取代的芳基团或可取代的杂环芳基团。]
• DIAMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PLANT DISEASE CONTROL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT
  申请人：Mitsui Chemicals, Inc.

  公开号：EP1681285A1

  公开（公告）日：2006-07-19

  It is an object of the present invention to provide a diamine derivative, a process for producing the same, and a plant disease control agent containing the above-described compound as an active ingredient. According to the present invention, a diamine derivative represented by Formula (1), a process for producing the same, and a plant disease control agent containing the above-described compound as an active ingredient are provided. [In Formula, R1 represents, for example, a halogenated hydrocarbon having the carbon number of 1 to 6; R2 and R7 independently represent, for example, a hydrogen atom or a hydrocarbon having the carbon number of 1 to 6; R3 and R4 independently represent, for example, a hydrogen atom or a hydrocarbon which has the carbon number of 1 to 6 and which may be substituted, or represent a cycloalkyl group having the carbon number of 3 to 6 including a carbon atom bonding to R3 and R4; R5 and R6 independently represent, for example, a hydrogen atom or a hydrocarbon group having the carbon number of 1 to 6; and R8 represents an arylalkyl group which may be substituted, an aryl group which may be substituted, or a heteroaryl group which may be substituted.]

  本发明的目的是提供一种二胺衍生物、一种生产二胺衍生物的工艺以及一种含有上述化合物作为活性成分的植物病害控制剂。 根据本发明，提供了一种由式（1）表示的二胺衍生物、一种生产该衍生物的工艺以及一种含有上述化合物作为活性成分的植物病害防治剂。 [在式中，R1 代表例如碳原子数为 1 至 6 的卤代烃；R2 和 R7 独立地代表例如氢原子或碳原子数为 1 至 6 的烃；R3 和 R4 独立地代表例如氢原子或碳原子数为 1 至 6 且可被取代的烃，或代表碳原子数为 3 至 6 的环烷基，包括与 R3 和 R4 键合的碳原子；R5 和 R6 独立地代表例如氢原子或碳原子数为 1-6 的烃基；以及 R8 代表可被取代的芳烷基、可被取代的芳基或可被取代的杂芳基。]