N-phenethylphenothiazine | 68825-26-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻嗪类
• 英文名称: N-phenethylphenothiazine
• 英文别名: 10-phenethyl-10H-phenothiazine；10-(2-phenylethyl)phenothiazine
• CAS: 68825-26-3
• 化学式: C₂₀H₁₇NS
• 分子量: 303.428
• InChiKey: CDGMAOXFJJBPPM-UHFFFAOYSA-N

物化性质

• 沸点：
  469.0±25.0 °C(Predicted)
• 密度：
  1.190±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  22
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  28.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  吩噻嗪 、 1,1-二甲氧基-2-苯基乙烷 在 三乙基硅烷 、 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 以96%的产率得到N-phenethylphenothiazine
  参考文献：
  名称：

  烯醇醚对芳香胺和N-杂环的还原N-芳基乙基化

  摘要：

  摘要 以（2-甲氧基乙烯基）（杂）芳烃为结构单元，以三乙基硅烷/三氟乙酸为还原剂，开发了一种在温和的还原条件下芳族胺和杂环的N-芳基乙基化的简便方法。该协议可与许多官能团兼容，并且脂肪族胺由于质子化而呈惰性。 以（2-甲氧基乙烯基）（杂）芳烃为结构单元，以三乙基硅烷/三氟乙酸为还原剂，开发了一种在温和的还原条件下芳族胺和杂环的N-芳基乙基化的简便方法。该协议可与许多官能团兼容，并且脂肪族胺由于质子化而呈惰性。

  DOI：

  10.1055/s-0036-1591859

文献信息

• POLYMERIZATION INHIBITOR COMPOSITION AND METHOD OF INHIBITING POLYMERIZATION OF DISTILLABLE MONOMERS
  申请人：Dow Global Technologies LLC

  公开号：EP2398832A1

  公开（公告）日：2011-12-28
• SYNERGISTIC POLYMERIZATION INHIBITOR COMPOSITION AND METHOD
  申请人：Dow Global Technologies LLC

  公开号：EP2683748A1

  公开（公告）日：2014-01-15
• [EN] POLYMERIZATION INHIBITOR COMPOSITION AND METHOD OF INHIBITING POLYMERIZATION OF DISTILLABLE MONOMERS<br/>[FR] COMPOSITION INHIBITRICE DE LA POLYMÉRISATION ET PROCÉDÉ D'INHIBITION DE LA POLYMÉRISATION DE MONOMÈRES DISTILLABLES
  申请人：DOW GLOBAL TECHNOLOGIES INC

  公开号：WO2010096512A1

  公开（公告）日：2010-08-26

  The present invention relates to a polymerization inhibitor composition and a method of inhibiting polymerization of distillable monomers in liquid and evaporated/condensed phases with the polymerization inhibitor composition. The polymerization inhibitor composition is useful for inhibiting polymerization of the distillable monomers during manufacture, purification (e.g., distillation), handling, and storage thereof.
• [EN] SYNERGISTIC POLYMERIZATION INHIBITOR COMPOSITION AND METHOD<br/>[FR] COMPOSITION SYNERGIQUE INHIBITRICE DE POLYMÉRISATION ET PROCÉDÉ AFFÉRENT
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2012121836A1

  公开（公告）日：2012-09-13

  Please be informed that the "follow up required item" does not work properly. For TOC and SL indication there is a follow-up required item although there is no warning in Bibadmin. See following example : A vinyl monomer polymerization inhibitor composition comprising a liquid mixture comprising a vinyl monomer and a polymerization inhibiting effective amount of a captive polymerization inhibitor, wherein the composition lacks a fugitive polymerization inhibitor of polymerization of the vinyl monomer and the captive polymerization inhibitor independently is characterizable as being an inhibitor of polymerization of the vinyl monomer and polymerization of the vinyl monomer is inhibited by the captive polymerization inhibitor, and wherein the captive polymerization inhibitor is a compound of formula (I): or a first acid addition salt thereof, wherein R1 is hydrogen or (C1-C3)alkyl.
• Reductive N-Arylethylation of Aromatic Amines and N-Heterocycles with Enol Ethers
  作者：Franz Bracher、Katharina Vögerl、Duc Ong

  DOI：10.1055/s-0036-1591859

  日期：2018.3

  N-arylethylation of aromatic amines and heterocycles under mild reductive conditions was developed using (2-methoxyvinyl)(hetero)arenes as building blocks and triethylsilane/trifluoroacetic acid as reducing agent. This protocol is compatible with numerous functional groups, and aliphatic amines are inert due to protonation. A convenient method for N-arylethylation of aromatic amines and heterocycles under

  摘要 以（2-甲氧基乙烯基）（杂）芳烃为结构单元，以三乙基硅烷/三氟乙酸为还原剂，开发了一种在温和的还原条件下芳族胺和杂环的N-芳基乙基化的简便方法。该协议可与许多官能团兼容，并且脂肪族胺由于质子化而呈惰性。 以（2-甲氧基乙烯基）（杂）芳烃为结构单元，以三乙基硅烷/三氟乙酸为还原剂，开发了一种在温和的还原条件下芳族胺和杂环的N-芳基乙基化的简便方法。该协议可与许多官能团兼容，并且脂肪族胺由于质子化而呈惰性。