The present invention relates generally to mitochondria protecting agents for treating diseases in which mitochondrial dysfunction leads to tissue degeneration and, more specifically, to compounds, compositions and methods related to the same. The methods of this invention involve administration of a pharmaceutically effective amount of a mitochondria protecting agent to a warm-blooded animal in need thereof, and composition of this invention contain a mitochondrial protecting agent in combination with a pharmaceutically acceptable carrier or diluent. Mitochondrial associated diseases which may be treated by the present invention include (but are not limited to) Alzheimer's Disease, diabetes mellitus, Parkinson's Disease, neuronal and cardiac ischemia, Huntington's disease and stroke.
本发明通常涉及用于治疗线粒体功能失调导致组织退化的疾病的线粒体保护剂,更具体地涉及与此相关的化合物、组合物和方法。本发明的方法涉及向需要此类保护剂的温血动物投予药学有效量的线粒体保护剂,并且本发明的组合物包含与药学可接受的载体或稀释剂结合的线粒体保护剂。本发明可以治疗的线粒体相关疾病包括(但不限于)阿尔茨海默病、糖尿病、帕
金森病、神经和心脏缺血、亨廷顿病和中风。