2-N-(imidazo[1,2-a]pyridin-2-ylmethyl)-4-nitrobenzene-1,2-diamine | 1381963-55-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并吡啶类
• 英文名称: 2-N-(imidazo[1,2-a]pyridin-2-ylmethyl)-4-nitrobenzene-1,2-diamine
• CAS: 1381963-55-8
• 化学式: C₁₄H₁₃N₅O₂
• 分子量: 283.29
• InChiKey: OSMLVWUXIMMMNQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  101
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  二氧化碳 、 2-N-(imidazo[1,2-a]pyridin-2-ylmethyl)-4-nitrobenzene-1,2-diamine 、 四丁基氟化铵 以98%的产率得到
  参考文献：
  名称：

  Reusable Amine-Based Structural Motifs for Green House Gas (CO₂) Fixation

  摘要：

  A series of compounds with an amine based structural motif (ASM) have been synthesized for efficient atmospheric CO2 fixation. The H-bonded ASM bicarbonate complexes were formed with an in situ generated HCO3- ion. The complexes have been characterized by IR, C-13 NMR, and X-ray single-crystal structural analysis. ASM bicarbonate salts have been converted to pure ASMs in quantitative yield under mild conditions for recycling processes.

  DOI：

  10.1021/ol301241k
• 作为产物：
  描述：

  4-硝基邻苯二胺 在 sodium tetrahydroborate 作用下， 以 甲醇 为溶剂， 生成 2-N-(imidazo[1,2-a]pyridin-2-ylmethyl)-4-nitrobenzene-1,2-diamine
  参考文献：
  名称：

  Reusable Amine-Based Structural Motifs for Green House Gas (CO₂) Fixation

  摘要：

  A series of compounds with an amine based structural motif (ASM) have been synthesized for efficient atmospheric CO2 fixation. The H-bonded ASM bicarbonate complexes were formed with an in situ generated HCO3- ion. The complexes have been characterized by IR, C-13 NMR, and X-ray single-crystal structural analysis. ASM bicarbonate salts have been converted to pure ASMs in quantitative yield under mild conditions for recycling processes.

  DOI：

  10.1021/ol301241k

文献信息

• Reduced Schiff-base assisted novel dihydrogenphosphate–water polymer
  作者：Sasanka Dalapati、Md. Akhtarul Alam、Sankar Jana、Nikhil Guchhait

  DOI：10.1039/c2ce25502b

  日期：——

  Reduced Schiff bases with a common p-nitro-o-phenylenediamine moiety have been synthesised and their structures have been characterized by single-crystal structural analysis. Schiff bases having self-complementary H-bond donors and H-bond acceptors can form a “scissors” like structure through intermolecular H-bonding interaction. Reduced Schiff bases interact with biologically important dihydrogenphosphate ion and form stable complexes. Furthermore, dihydrogenphosphate and water form an unprecedented self-assembled dihydrogenphosphate–water [H2PO4·H2O]nn− 1D supramolecular polymer upon complexation with reduced Schiff bases.

  合成了具有共通p-硝基-o-苯二胺基团的还原施夫碱，并通过单晶结构分析对其结构进行了表征。具有自互补氢键供体和氢键受体的施夫碱可以通过分子间氢键相互作用形成“剪刀”状结构。还原施夫碱与生物学上重要的二氢磷酸根离子相互作用，形成稳定的复合物。此外，二氢磷酸根和水在与还原施夫碱络合时形成前所未见的自组装二氢磷酸根-水 [H2PO4·H2O]nn⁻ 1D 超分子聚合物。
• A Molecular Lock and Key: “Unlocked-Locked” Conformational Switching of a Receptor by Anions
  作者：Sasanka Dalapati、Md. Akhtarul Alam、Sankar Jana、Rajat Saha、Saptarshi Biswas、Nikhil Guchhait

  DOI：10.1002/cplu.201100036

  日期：2012.2

  Lock up your valuables: Receptor 1 acts as a “molecular lock” and anions act as “keys”; H2PO4− can “lock” 1 by switching it from its “unlocked” conformation, however, the structurally similar HSO4− cannot “lock” receptor 1 as evidenced by single‐crystal X‐ray analysis (see scheme). The “unlocked–locked” conformational switching of 1 was investigated by monitoring changes in fluorescence intensity in

  锁上贵重物品：受体1充当“分子锁”，而阴离子充当“钥匙”；ħ 2 PO 4 -可以“锁定” 1通过从它的“解锁”构象切换它，但是，结构类似的HSO 4 -不能“锁”受体1如由单晶X射线分析（参见方案）。通过在存在不同阴离子的情况下监测荧光强度的变化，研究了1的“开锁”构象转换。
• Reusable Amine-Based Structural Motifs for Green House Gas (CO₂) Fixation
  作者：Sasanka Dalapati、Sankar Jana、Rajat Saha、Md. Akhtarul Alam、Nikhil Guchhait

  DOI：10.1021/ol301241k

  日期：2012.7.6

  A series of compounds with an amine based structural motif (ASM) have been synthesized for efficient atmospheric CO2 fixation. The H-bonded ASM bicarbonate complexes were formed with an in situ generated HCO3- ion. The complexes have been characterized by IR, C-13 NMR, and X-ray single-crystal structural analysis. ASM bicarbonate salts have been converted to pure ASMs in quantitative yield under mild conditions for recycling processes.