5-chloro-6-hydroxy-benzo[1,3]oxathiol-2-one | 22791-11-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 5-chloro-6-hydroxy-benzo[1,3]oxathiol-2-one
• 英文别名: 5-chloro-6-hydroxy-benz[1,3]oxathiol-2-one；5-Chlor-6-hydroxy-benz[1,3]oxathiol-2-on；5-Chloro-6-hydroxy-1,3-benzoxathiol-2-one
• CAS: 22791-11-3
• 化学式: C₇H₃ClO₃S
• 分子量: 202.618
• InChiKey: MKBDYVAYMJJUMD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  71.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  噻克索酮 在 盐酸 、 potassium chlorate 、 溶剂黄146 作用下， 生成 5-chloro-6-hydroxy-benzo[1,3]oxathiol-2-one
  参考文献：
  名称：

  Method of treating topical skin disorders with benzoxathiol compositions

  摘要：

  公开号：

  US02886488A1

文献信息

• Neuroprotective benzo 1 3 oxathiol 2 ones
  申请人：Jaquith B. James

  公开号：US20060234987A1

  公开（公告）日：2006-10-19

  This invention relates to benzo[1,3]oxathiol-2-ones, derivatives, and precursors thereof, and their use as neuroprotective agents in the treatment and prevention of neuronal disorders of the central and peripheral nervous systems.

  本发明涉及苯并[1,3]噁硫-2-酮、其衍生物和前体物，以及它们作为神经保护剂在治疗和预防中枢和外周神经系统的神经元疾病中的应用。
• Thiocarbonates of aromatic polyhydroxy compounds
  申请人：WINTHROP CHEM CO INC

  公开号：US02332418A1

  公开（公告）日：1943-10-19
• SPT5 INHIBITORS AND USES THEREOF
  申请人：Yeda Research and Development Co. Ltd.

  公开号：US20210379060A1

  公开（公告）日：2021-12-09

  Provided are compounds which are Spt5 inhibitors and which are for use in the treatment diseases and disorders in which inhibiting one or more activities of Spt5 is beneficial, such as, for example, Trinucleotide repeat disorders, obesity, inflammatory diseases, infectious diseases and cancer. The compounds are represented by Formulae I-VII, as defined in the specification.
• Method of treating topical skin disorders with benzoxathiol compositions
  申请人：THOMAE GMBH DR K

  公开号：US02886488A1

  公开（公告）日：1959-05-12