8α,14β-Oestron | 35938-00-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 8α,14β-Oestron
• 英文别名: (8S,9S,13S,14R)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
• CAS: 35938-00-2
• 化学式: C₁₈H₂₂O₂
• 分子量: 270.371
• InChiKey: DNXHEGUUPJUMQT-HPFXQQBRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  20
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  8α,14β-Oestron 、 苯甲酰氯 生成 (13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl) benzoate
  参考文献：
  名称：

  High-efficiency regnerationin vitro from potato petioles with intact leaflets

  摘要：

  The shoot/plantlet regeneration in vitro of seven potato (Solanum tuberosum L.) cultivars from petioles with intact leaflets was assessed using six treatment combinations - a basal medium with or without silver thiosulphate (STS) or thidiazuron (TDZ) at two concentrations (2 or 0.5 mg/l) of the indoleacetic acid (IAA). The basal medium consisted of Murashige and Skoog (IMS) salts and vitamins supplemented with 3 mg/l 6-benzylaminopurine, and 1 mg/l gibberellic acid, 30 g/l sucrose, and 7.0 g/l PHY-TOAGAR. TWO full sets repeats and one partial set repeat of independent experiments were conducted and all produced similar results. Silver thiosulphate decreased the regeneration frequency and number of shoots peer callus. No significant changes were observed with thidiazuron. Regeneration rates of (100%) with up to 20 shoots/plantlets per callus were achieved at 2 mg/l IAA with cultivars Desiree, Kennebec, Niska, and Lenape. These cultivars still showed high regeneration rates (87%-98%) on media with 0.5 mg/l IAA, and good regeneration rates were also achieved by the other three cultivars (48%, 94%, and 50% for Chieftain, Russet Burbank, and Shepody, respectively). Even with the single medium protocol (0.5% IAA without thiosulphate or thidiazuron), Desiree, Lenape, and Niska exhibited a regeneration rate of 98%. The use of petiole-with-leaflet explants could be ideal for the regeneration step of potato genetic transformation protocol because of their high regeneration efficiency and their small cut surface area for Agrobacterium elimination after co-incubation.

  DOI：

  10.1007/bf02874770
• 作为产物：
  描述：

  8(9),14(15)-bisdehydroestrone 在 mer-trihydridotris(triphenylphosphine)iridium(III) 、 氢气 作用下， 以 三氟乙酸 为溶剂， 50.0~70.0 ℃ 、9.81 MPa 条件下， 反应 40.0h， 以1%的产率得到雌酚酮
  参考文献：
  名称：

  Catalytic ionic hydrogenation of 8(9),14(15)-bisdehydroestrone, 8(9),14(15)-bisdehydro-d-homoestrone, and their derivatives

  摘要：

  DOI：

  10.1007/bf00949495

文献信息

• Catalytic ionic hydrogenation of 8(9),14(15)-bisdehydroestrone, 8(9),14(15)-bisdehydro-d-homoestrone, and their derivatives
  作者：G. G. Vasiyarov、M. I. Kalinkin、S. N. Ananchenko、G. D. Kolomnikova、I. V. Torgov、Z. N. Parnes、D. N. Kursanov

  DOI：10.1007/bf00949495

  日期：1981.9
• High-efficiency regnerationin vitro from potato petioles with intact leaflets
  作者：Shirley Yee、Birt Stevens、Shirlyn Coleman、Jane E. A. Seabrook、Xiu-Qing Li

  DOI：10.1007/bf02874770

  日期：2001.3

  The shoot/plantlet regeneration in vitro of seven potato (Solanum tuberosum L.) cultivars from petioles with intact leaflets was assessed using six treatment combinations - a basal medium with or without silver thiosulphate (STS) or thidiazuron (TDZ) at two concentrations (2 or 0.5 mg/l) of the indoleacetic acid (IAA). The basal medium consisted of Murashige and Skoog (IMS) salts and vitamins supplemented with 3 mg/l 6-benzylaminopurine, and 1 mg/l gibberellic acid, 30 g/l sucrose, and 7.0 g/l PHY-TOAGAR. TWO full sets repeats and one partial set repeat of independent experiments were conducted and all produced similar results. Silver thiosulphate decreased the regeneration frequency and number of shoots peer callus. No significant changes were observed with thidiazuron. Regeneration rates of (100%) with up to 20 shoots/plantlets per callus were achieved at 2 mg/l IAA with cultivars Desiree, Kennebec, Niska, and Lenape. These cultivars still showed high regeneration rates (87%-98%) on media with 0.5 mg/l IAA, and good regeneration rates were also achieved by the other three cultivars (48%, 94%, and 50% for Chieftain, Russet Burbank, and Shepody, respectively). Even with the single medium protocol (0.5% IAA without thiosulphate or thidiazuron), Desiree, Lenape, and Niska exhibited a regeneration rate of 98%. The use of petiole-with-leaflet explants could be ideal for the regeneration step of potato genetic transformation protocol because of their high regeneration efficiency and their small cut surface area for Agrobacterium elimination after co-incubation.