2-(1,1-dimethylethyl)-2,3-dihydro-1,4-naphthoquinone | 122271-19-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2-(1,1-dimethylethyl)-2,3-dihydro-1,4-naphthoquinone
• 英文别名: 2-Tert-butyl-2,3-dihydronaphthalene-1,4-dione
• CAS: 122271-19-6
• 化学式: C₁₄H₁₆O₂
• 分子量: 216.28
• InChiKey: YYMMMTFFJKLLGG-UHFFFAOYSA-N

物化性质

• 沸点：
  343.4±22.0 °C(Predicted)
• 密度：
  1.106±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  叔丁基(氯)汞 、 1,4-萘醌 在 溶剂黄146 作用下， 以 二甲基亚砜 为溶剂， 生成 2-(1,1-dimethylethyl)-2,3-dihydro-1,4-naphthoquinone
  参考文献：
  名称：

  烷基汞卤化物的均裂碱促进芳族烷基化1

  摘要：

  在质子受体的存在下，可以用烷基汞卤化物观察到导致电负性取代的苯衍生物取代的电子转移链反应，例如……

  DOI：

  10.1021/ja971809n

文献信息

• PREPARATION OF DIAZO AND DIAZONIUM COMPOUNDS
  申请人：Raines Ronald Thaddeus

  公开号：US20100125132A1

  公开（公告）日：2010-05-20

  A method for making diazo-compounds, diazonium salts thereof and other protected forms of these compounds. Diaz-compounds are prepared by reaction of a tertiary phosphine reagent carrying a reactive carbonyl group with an azide. The reaction can also generate an acyl triazene which can be converted thermally or by addition of base to form the diazo-compound or the acyl triazene can be isolated. The method is particularly useful for conversion of azides carrying one or more electron withdrawing groups to diazo-compounds. The method can be carried out in aqueous medium under mild conditions and is particularly useful for conversion of azido sugars to diazo-compound and diazonium salts thereof under physiological conditions. Tertiary phosphine reagents, particularly those that are water-soluble, and precursors for preparation of the reagents are provided.

  一种制备重氮化合物、其重氮盐和这些化合物的其他保护形式的方法。通过将携带反应性羰基基团的三级膦试剂与偶氮化物反应来制备重氮化合物。该反应还可以生成酰基三氮烯，可以通过热转化或加入碱来形成重氮化合物，或者可以分离出酰基三氮烯。该方法特别适用于将携带一个或多个电子吸引基团的偶氮化物转化为重氮化合物。该方法可以在温和条件下在水性介质中进行，并且特别适用于在生理条件下将偶氮糖转化为重氮化合物和其重氮盐。提供了三级膦试剂，特别是那些水溶性的试剂，以及用于制备这些试剂的前体。
• Preparation of Diazo and Diazonium Compounds
  申请人：RAINES Ronald Thaddeus

  公开号：US20130203974A1

  公开（公告）日：2013-08-08

  A method for making diazo-compounds, diazonium salts thereof and other protected forms of these compounds. Diaz-compounds are prepared by reaction of a tertiary phosphine reagent carrying a reactive carbonyl group with an azide. The reaction can also generate an acyl triazene which can be converted thermally or by addition of base to form the diazo-compound or the acyl triazene can be isolated. The method is particularly useful for conversion of azides carrying one or more electron withdrawing groups to diazo-compounds. The method can be carried out in aqueous medium under mild conditions and is particularly useful for conversion of azido sugars to diazo-compound and diazonium salts thereof under physiological conditions. Tertiary phosphine reagents, particularly those that are water-soluble, and precursors for preparation of the reagents are provided.

  一种制备重氮化合物、其重氮盐和这些化合物的其他保护形式的方法。通过将带有反应性羰基基团的三级膦试剂与叠氮化物反应来制备重氮化合物。该反应也可以生成酰基三氮烯，可以通过热转化或加入碱来形成重氮化合物，或者可以分离出酰基三氮烯。该方法特别适用于将带有一个或多个电子提取基团的叠氮化合物转化为重氮化合物。该方法可以在温和条件下在水介质中进行，特别适用于在生理条件下将叠氮糖转化为重氮化合物和其重氮盐。提供了三级膦试剂，特别是那些水溶性的试剂和制备试剂的前体。
• Electron transfer processes. 48. Free-radical alkylations of enones involving proton transfers
  作者：Glen A. Russell、Byeong Hyo Kim、Shekhar V. Kulkarni

  DOI：10.1021/jo00277a004

  日期：1989.8
• US8350014B2
  申请人：——

  公开号：US8350014B2

  公开（公告）日：2013-01-08
• US8871916B2
  申请人：——

  公开号：US8871916B2

  公开（公告）日：2014-10-28