N,N-iminodiethanoldithiocarbamic acid | 1528-72-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-iminodiethanoldithiocarbamic acid
• 英文别名: bis(2-hydroxyethyl)dithiocarbamate；Dihydroxyethyldithiocarbamate；diethanoldithiocarbamic acid；bis-(2-hydroxy-ethyl)-dithiocarbamic acid；Bis-(2-hydroxy-aethyl)-dithiocarbamidsaeure；Bis-<2-hydroxy-ethyl>-carbaminsaeure；bis(2-hydroxyethyl)carbamodithioic acid
• CAS: 1528-72-9
• 化学式: C₅H₁₁NO₂S₂
• 分子量: 181.28
• InChiKey: PCBLZWZCGNKODY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.5
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  76.8
• 氢给体数：
  3
• 氢受体数：
  4

安全信息

• 海关编码：
  2930909090

反应信息

• 作为反应物：
  描述：

  N,N-iminodiethanoldithiocarbamic acid 生成 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Kagan-Scherlin; Ssucharewa, 1935, vol. 12, p. 930

  摘要：

  DOI：
• 作为产物：
  描述：

  二硫化碳 、 二乙醇胺 以 乙醇 为溶剂， 生成 N,N-iminodiethanoldithiocarbamic acid
  参考文献：
  名称：

  CoFe2O4/CdS 纳米复合材料：制备、表征和在有机染料污染物的声催化降解中的应用

  摘要：

  通过在CoFe 2 O 4 纳米颗粒表面在200℃的低温下一步水热分解二乙醇二硫代氨基甲酸镉配合物，制备了磁性CoFe 2 O 4 /CdS纳米复合材料。通过X射线衍射(XRD)、傅里叶变换红外光谱(FT-IR)、扫描电子显微镜、能量色散X射线光谱(EDX)、紫外-可见光谱、透射电子显微镜(TEM)、 N 2 气体吸附分析、X 射线光电子能谱 (XPS) 和振动样品磁强计。FT-IR、XRD、EDX 和 XPS 结果证实了 CoFe 2 O 4 /CdS 纳米复合材料的形成。根据 TEM 分析，CoFe 2 O 4 /CdS 纳米复合材料构成几乎均匀的球状纳米颗粒，尺寸约为 20 nm。CoFe 2 O 4 /CdS 纳米复合材料的光吸收光谱显示带隙为 2.21 eV，这使其成为适用于声波/光催化降解有机污染物的候选者。因此，CoFe 2 O 4 /CdS纳米复合材料的声催化活性被评估为在

  DOI：

  10.1016/s1872-2067(16)62473-7

文献信息

• Structural and electronic effects of alkyl substituents on the main group dithiocarbamato complexes: crystal and molecular structures of tris(N,N′-iminodiethanoldithiocarbamato)metal(III) complexes (M  As, Sb and Bi) and cyclic voltammetric studies on substituted dithiocarbamates
  作者：V. Venkatachalam、K. Ramalingam、U. Casellato、R. Graziani

  DOI：10.1016/s0277-5387(96)00362-2

  日期：1997.1

  −CH2CH2OH groups increases, the peak currents increase. In the case of Bi complexes, the reduction process tends to become reversible. In addition, the larger peak current associated with the third response indicates the possible reduction of Bi(dtc)2(DMF)n. In all the complexes the dtc− ion was lost from M(dtc)3− species, with oxidation around +0.6 V in the reverse scans. The crystal structures of As(deadtc)3

  摘要用玻璃碳工作电极对AsIII，SbIII和BiIII的各种二硫代氨基甲酸酯与二乙基二硫代氨基甲酸（dedtc），N-甲基氨基乙醇二硫代氨基甲酸（nmedtc）和N，N'-亚氨基二乙醇二硫代氨基甲酸进行了循环伏安还原研究。对于As和Sb配合物，单电子还原过程发生在-1.0 V左右，对于Bi配合物，发生单电子还原过程在-0.5 V左右，这是完全不可逆的。分子极性末端的连接由还原前和还原后的吸附过程指示。随着-CH 2 CH 2 OH基团数目的增加，峰值电流增加。在Bi配合物的情况下，还原过程趋于可逆。此外，与第三响应相关的较大峰值电流表明Bi（dtc）2（DMF）n可能降低。在所有络合物中，dtc-离子均从M（dtc）3-物种中丢失，在反向扫描中氧化程度约为+0.6V。通过单晶X射线分析确定As（deadtc）3（1），Sb（deadtc）3（2）和Bi（deadtc）3（3）的晶体结构。
• Sodium Chlorite - Yet Another Oxidant for Thiols to Disulphides
  作者：Krishnamurthy Ramadas、Natarajan Srinivasan

  DOI：10.1080/00397919508010811

  日期：1995.1

  An efficient oxidative coupling of thiols to disulphides is described using sodium chlorite which has good synthetic and commercial relevance.
• Synthesis, antifungal activities and molecular docking studies of novel 2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl dithiocarbamates
  作者：Yan Zou、Shichong Yu、Renwu Li、Qingjie Zhao、Xiang Li、Maocheng Wu、Ting Huang、Xiaoxun Chai、Honggang Hu、Qiuye Wu

  DOI：10.1016/j.ejmech.2014.01.009

  日期：2014.3

  A series of 2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl dithiocarbamates as new analogs of fluconazole were synthesized and their antifungal activities were evaluated. Among these compounds, 2a-f and 3a-q exhibited higher activities than fluconazole against nearly all fungi tested except Aspergillus fumigatus. Noticeably, the in vitro biological activities of 2b, 3a, 3c, 3h-k, and 3o-q against Candida species were much better than those of fluconazole and ketoconazole. Also, 2a-d, 3a-d, 3e-f, 3h-k, 3p and 3q showed higher activities against A. fumi than fluconazole. Computational docking experiments indicated that the inhibition of CYP51 involved a coordination bond with iron of the heme group, the hydrophilic H-bonding region, the hydrophobic region, and the narrow hydrophobic cleft. (C) 2014 Elsevier Masson SAS. All rights reserved.
• Nichols, Peter J.; Grant, Michael W., Australian Journal of Chemistry, 1989, vol. 42, # 7, p. 1085 - 1102
  作者：Nichols, Peter J.、Grant, Michael W.

  DOI：——

  日期：——
• Pandeya, Krishna B.; Kaul, Bharat B., Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry, 1982, vol. 12, p. 259 - 268
  作者：Pandeya, Krishna B.、Kaul, Bharat B.

  DOI：——

  日期：——