SF-150B(1) | 114390-43-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: SF-150B(1)
• 英文别名: SF-150B；N-[2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]phenyl]acetamide
• CAS: 114390-43-1
• 化学式: C₁₆H₂₂Br₂N₂O
• 分子量: 418.171
• InChiKey: RJDFZIYOLCRAPR-UHFFFAOYSA-N

物化性质

• 沸点：
  498.7±45.0 °C(Predicted)
• 密度：
  1.53±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  32.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  盐酸溴己新 、 乙酰氯 生成 SF-150B(1)
  参考文献：
  名称：

  Goeber, B.; Lisowski, Hannelore; Franke, P., Pharmazie, 1988, vol. 43, # 1, p. 23 - 26

  摘要：

  DOI：

文献信息

• COMBINATION OF A COMPOUND HAVING THE ABILITY TO REARRANGE A LYSOSOMAL ENZYME AND AMBROXOL AND/OR A DERIVATIVE OF AMBROXOL
  申请人：Centogene IP GmbH

  公开号：EP2793872B1

  公开（公告）日：2021-03-10
• Combination of a Compound Having the Ability to Rearrange a Lysosomal Enzyme and Ambroxol and/or a Derivative of Ambroxol
  申请人：Centogene IP GmbH

  公开号：US20210228560A1

  公开（公告）日：2021-07-29

  The present invention is related to a combination comprising a first constituent and a second constituent, wherein the first constituent is a compound having the ability to rearrange a lysosomal protein, wherein the lysosomal protein has a reduced activity, and wherein the second constituent is Ambroxol and/or a derivative of Ambroxol.
• [EN] COMBINATION OF A COMPOUND HAVING THE ABILITY TO REARRANGE A LYSOSOMAL ENZYME AND AMBROXOL AND/OR A DERIVATIVE OF AMBROXOL<br/>[FR] COMBINAISON D'UN COMPOSÉ AYANT L'APTITUDE À RÉARRANGER UNE ENZYME LYSOSOMALE ET D'AMBROXOL ET/OU D'UN DÉRIVÉ D'AMBROXOL
  申请人：CENTOGENE GMBH

  公开号：WO2013091897A1

  公开（公告）日：2013-06-27

  It is herewith declared that the information stored on the carrier which is submitted together with the international patent application is identical to the written sequence listing of the international patent application.
• Goeber, B.; Lisowski, Hannelore; Franke, P., Pharmazie, 1988, vol. 43, # 1, p. 23 - 26
  作者：Goeber, B.、Lisowski, Hannelore、Franke, P.

  DOI：——

  日期：——