2-dimethylamino-1,1-diphenylethanol | 5612-62-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-dimethylamino-1,1-diphenylethanol
• 英文别名: 2-Dimethylamino-1,1-diphenyl-aethanol；N,N-Dimethyl-2-hydroxy-2.2-diphenyl-aethylamin；1,1-Diphenyl-2-dimethylamino-aethanol-(1)；1,1-Diphenyl-2-(dimethylamino)-aethanol；2-Dimethylamino-1,1-diphenyl-aethanol-(1)；2-(Dimethylamino)-1,1-diphenylethanol
• CAS: 5612-62-4
• 化学式: C₁₆H₁₉NO
• 分子量: 241.333
• InChiKey: UHXAXULDXONRCR-UHFFFAOYSA-N

物化性质

• 熔点：
  45-46 °C
• 沸点：
  175-180 °C(Press: 15 Torr)
• 密度：
  1.077±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  23.5
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 海关编码：
  2922199090

反应信息

• 作为反应物：
  描述：

  2-dimethylamino-1,1-diphenylethanol 在 盐酸 作用下， 生成 联苯乙醛
  参考文献：
  名称：

  Beiträge zum Problem der Beziehungen zwischen Konstitution und Wirkung. 1,1-Diaryl-2=aminoalkanole-(1)

  摘要：

  DOI：

  10.1002/ardp.19422800202
• 作为产物：
  描述：

  (2,4,6-tritert-butylphenyl) N-(2-hydroxy-2,2-diphenylethyl)-N-methylcarbamate 在 lithium aluminium tetrahydride 作用下， 以 1,4-二氧六环 为溶剂， 生成 2-dimethylamino-1,1-diphenylethanol
  参考文献：
  名称：

  Seebach,D.; Hassel,T., Angewandte Chemie, 1978, vol. 90, p. 296 - 297

  摘要：

  DOI：

文献信息

• Convenient Preparation of 1-(<i>N,N</i>-Dialkylamino)alkyltributylstannanes from 1-(<i>N,N</i>-Dialkylamino)alkylbenzotriazoles
  作者：Alan R. Katritzky、He-Xi Chang、Jing Wu

  DOI：10.1055/s-1994-25598

  日期：——

  The title compounds have been prepared conveniently and in high yield from 1-(N,N-dialkylamino)alkyltributylbenzotriazoles and tributyltinlithium.

  标题化合物是由 1-(N,N-二烷基氨基)烷基三丁基苯并三唑和三丁基锡锂以高产率方便地制备出来的。
• Novel Stannatranes of the Type N(CH₂CMe₂O)₃SnX (X = OR, SR, OC(O)R, SP(S)Ph₂, Halogen). Synthesis, Molecular Structures, and Electrochemical Properties
  作者：Thomas Zöller、Christina Dietz、Ljuba Iovkova-Berends、Olga Karsten、Gerrit Bradtmöller、Ann-Kristin Wiegand、Yu Wang、Viatcheslav Jouikov、Klaus Jurkschat

  DOI：10.1021/ic202179e

  日期：2012.1.16

  The syntheses of the stannatrane derivatives of the type N(CH2CMe2O)(3)SnX (1, X = Ot-Bu; 2, X = Oi-Pr; 3, X = 2,6-Me2C6H3O; 4, X = p-t-BuC6H4O; 5, X = p-NO2C6H4O; 6, X = p-FC6H4O; 7, X = p-PPh2C6H4O; 8, X = p-MeC6H4S; 9, X = o-NH2C6H4O; 10, X = OCPh2CH2NMe2; 11, X = Ph2P(S)S; 12, X = p-t-BuC6H4C(O)O; 13, X = Cl; 14, X = Br; 15, X = I; 16, X = p-N(CH2CMe2O)(3)SnOSiMe2C6H4SiMe2O) are reported. The compounds are characterized by X-ray diffraction analyses (3-8, 11-16), multinuclear NMR spectroscopy, C-13 CP MAS (14) and Sn-119 CP MAS NMR (13, 14) spectroscopy, mass spectrometry and osmometric molecular weight determination (13). Electrochemical measurements show that anodic oxidation of the stannatranes 4 and 8 occurs via electrochemically reversible electron transfer resulting in the corresponding cation radicals. The latter were detected by cyclic voltammetry (CV) and real-time electron paramagnetic resonance spectroscopy (EPR). DFT calculations were performed to compare the stannatranes 4, 8, and 13 with the corresponding cation radicals 4(+center dot), 8(+center dot), and 13(+center dot), respectively.
• Seebach,D. et al., Chemische Berichte, 1976, vol. 109, p. 1309 - 1323
  作者：Seebach,D. et al.

  DOI：——

  日期：——
• Wittig; Mangold; Felletschin, Justus Liebigs Annalen der Chemie, 1948, vol. 560, p. 116,123
  作者：Wittig、Mangold、Felletschin

  DOI：——

  日期：——
• Bogatkov,S.V.; Cherkasova,E.M., Journal of general chemistry of the USSR, 1969, vol. 39, p. 1823 - 1831
  作者：Bogatkov,S.V.、Cherkasova,E.M.

  DOI：——

  日期：——