1,4:3,6-dianhydro-L-glucitol | 124508-14-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 呋喃类
• 英文名称: 1,4:3,6-dianhydro-L-glucitol
• 英文别名: 1,4:3,6-dianhydrosorbitol；Isosorbide；isosorbitol；(3S,3aS,6R,6aS)-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3,6-diol
• CAS: 124508-14-1
• 化学式: C₆H₁₀O₄
• 分子量: 146.143
• InChiKey: KLDXJTOLSGUMSJ-FSIIMWSLSA-N

物化性质

• 沸点：
  372.1±42.0 °C(Predicted)
• 密度：
  1.475±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.4
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  58.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,4:3,6-dianhydro-L-glucitol 在 potassium carbonate 、 间氯过氧苯甲酸 作用下， 以 氯仿 、 甲苯 为溶剂， 反应 34.0h， 生成 2-O-(2,3-Epoxypropyl)-isoidide
  参考文献：
  名称：

  Stoss; Schluter; Axmann, Arzneimittel-Forschung/Drug Research, 1990, vol. 40, # 1, p. 13 - 18

  摘要：

  DOI：
• 作为产物：
  描述：

  2,6-dibromo-2,6-dideoxy-D-glucitol 在 氢氧化钾 作用下， 反应 0.5h， 以74%的产率得到1,4:3,6-dianhydro-L-glucitol
  参考文献：
  名称：

  Bock, Klaus; Castilla, Ines Maya; Lundt, Inge, Acta Chemica Scandinavica, 1989, vol. 43, # 3, p. 264 - 268

  摘要：

  DOI：

文献信息

• 아이소소바이드 유도체, 액정 조성물, 액정 소자 및 액정 표시 장치
  申请人：SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 가부시키가이샤 한도오따이 에네루기 켄큐쇼(519980839048)

  公开号：KR20150015418A

  公开（公告）日：2015-02-10

  본 발명은 다양한 액정 표시 장치에 적용하는 것이 가능한 신규 액정 조성물용 재료를 제공한다. 일반식(G2)으로 나타내어지는 신규 아이소소바이드 유도체를 제공한다. 일반식(G2)에서, Ar, Ar, Ar, 및 Ar는 각각 독립적으로, 치환 또는 비치환된 탄소수 6~12의 아릴렌기, 치환 또는 비치환된 탄소수 3~12의 사이클로알킬렌기, 또는 치환 또는 비치환된 탄소수 4~12의 사이클로알케닐렌기를 나타내고, l, k, m, 및 n은 각각 독립적으로 0~3을 나타낸다. 또한, R 및 R은 각각 독립적으로 산소, 단결합, 또는 치환 또는 비치환된 탄소수 1~12의 알킬렌기를 나타낸다. R 및 R는 각각 독립적으로 수소, 산소, 치환 또는 비치환된 탄소수 1~12의 알킬기, 또는 치환 또는 비치환된 탄소수 1~12의 알콕시기를 나타낸다.

  本发明提供了一种可以应用于各种液晶显示器件的新型液晶配方材料。该配方提供了一种表示为一般式(G2)的新型异硫氮杂环化合物。在一般式(G2)中，Ar，Ar，Ar和Ar分别独立地表示取代或未取代的含有6~12个碳原子的芳基，取代或未取代的含有3~12个碳原子的环烷基，或取代或未取代的含有4~12个碳原子的环烷烯基，l，k，m和n分别独立地表示0~3。此外，R和R分别独立地表示氧、单键或含有1~12个碳原子的取代或未取代的烷基。R和R分别独立地表示氢、氧、含有1~12个碳原子的取代或未取代的烷基，或含有1~12个碳原子的取代或未取代的醇基。
• Cation and leaving group effects in isosorbide alkylation under microwave in phase transfer catalysis
  作者：Saber Chatti、Michel Bortolussi、André Loupy

  DOI：10.1016/s0040-4020(01)00318-0

  日期：2001.5

  leaving group effects and influence of catalyst under phase transfer catalysis conditions using concomitant microwave irradiation during di-n-octylation of isosorbide. A small amount of solvent was necessary to control temperature and to provide good yields within a few minutes. The yields were dramatically improved when compared to conventional heating under the same conditions, in spite of similar profiles

  我们已经研究了在异山梨醇二正辛基化过程中伴随微波辐射在相转移催化条件下的阳离子，盐，离去基团效应和催化剂的影响。为了控制温度并在几分钟内提供良好的收率，需要少量的溶剂。尽管温度升高曲线相似，但与在相同条件下的常规加热相比，产率却得到了显着提高。
• Novel photo-polymerizable chiral hydrogen-bonded self-assembled complexes: Preparation, characterization and the utilization as a thermal switching reflective color film
  作者：Fengjin Chen、Jinbao Guo、Zhijian Qu、Jie Wei

  DOI：10.1039/c0jm03810e

  日期：——

  In this study, novel photopolymerizable chiral hydrogen-bonded self-assembled complexes (PCHSCs) were fabricated, which were derived from photopolymerizable 4-(6-acryloyloxyhexyloxy) benzoic acid (AHBA, proton donor) and chiral pyridine derivatives (proton acceptor). Their structures were characterized by fourier transform infrared (FT-IR) and the proton nuclear magnetic resonance (1H-NMR) spectoscopy. The thermal stability, phase behaviors and helical twisted power (HTP) characteristics of the PCHSC were investigated by measuring the variable-temperature FT-IR spectrum, differential scanning calorimetry (DSC), polarizing optical microscopy (POM) and the Cano wedge. The results demonstrate that all the PCHSCs have good thermal stability within a temperature range, and the pitch length of all the cells containing the PCHSCs increases with increasing temperature, which is due to the fact that the HTP values of all the PCHSCs decrease with an increase of temperature. What's more, the introduction of AHBA leads to chiral enhancement of the PCHSCs. Based on the above results, a polymer stabilized cholesteric liquid crystals (PSCLCs) composite with the above PCHSCs was prepared and the thermal-optical characteristics of the PSCLCs film were investigated. The results confirm that the reflective wavelength of the PSCLCs film before and after irradiation can be thermally switched to reflect green and red color from the initial state reflecting a blue/green color with the temperature increasing from 30 °C to 75 °C. On the basis of this mechanism, the novel material in this study can be used as optical/photonic paper, optical sensors and LCs displays, etc.

  本研究制备了新型可光聚合手性氢键自组装复合物（PCHSCs），它们来自可光聚合的 4-（6-丙烯酰氧基己氧基）苯甲酸（AHBA，质子供体）和手性吡啶衍生物（质子受体）。傅立叶变换红外光谱（FT-IR）和质子核磁共振光谱（1H-NMR）对它们的结构进行了表征。通过测量变温傅立叶变换红外光谱、差示扫描量热法（DSC）、偏振光学显微镜（POM）和卡诺楔仪，研究了 PCHSC 的热稳定性、相行为和螺旋扭曲力（HTP）特性。结果表明，所有 PCHSC 在一定温度范围内都具有良好的热稳定性，所有含有 PCHSC 的细胞的间距长度都随着温度的升高而增加，这是因为所有 PCHSC 的 HTP 值都随着温度的升高而降低。此外，AHBA 的引入还导致了 PCHSC 的手性增强。基于上述结果，制备了含有上述 PCHSCs 的聚合物稳定胆固醇液晶（PSCLCs）复合材料，并研究了 PSCLCs 薄膜的热光学特性。结果证实，随着温度从 30 °C 升高到 75 °C，PSCLCs 薄膜在辐照前后的反射波长可发生热转换，从最初的反射蓝/绿颜色转变为反射绿/红颜色。基于这一机理，本研究中的新型材料可用作光学/光子纸、光学传感器和液晶显示器等。
• [EN] USE OF COMPOUNDS RESULTING FROM A SUGAR POLYOL OR FROM A DEHYDROGENATED SUGAR POLYOL DERIVATIVE AS A UV-SCREENING AGENT; ANTISUN COMPOSITIONS CONTAINING SAME; AND NOVEL COMPOUNDS<br/>[FR] UTILISATION DES COMPOSÉS OBTENUS À PARTIR D'UN POLYOL DE TYPE SUCRE OU D'UN DÉRIVÉ DÉSHYDROGÉNÉ DE POLYOL DE TYPE SUCRE À TITRE D'AGENT DE FILTRATION UV ; COMPOSITIONS ANTISOLAIRES LES CONTENANT ; ET NOUVEAUX COMPOSÉS
  申请人：OREAL

  公开号：WO2012010554A1

  公开（公告）日：2012-01-26

  The present invention relates to the cosmetic use, as an agent for screening out UV radiation, of compounds resulting from a sugar polyol or from a dehydrogenated sugar polyol derivative of formula (I) or (II) in which A1 and A2 denote UV-screening groups; Z1 and Z2 a sugar polyol group or a dehydrogenated sugar polyol derivative such that the product of formula (I) has in its structure from 1 to 4 -OH groups remaining and optionally from 1 to 2 -COOH groups. The present invention also relates to a composition comprising, in a cosmetically acceptable medium, at least one compound of formula (I) or (II). The present invention also relates to novel compounds resulting from a sugar polyol or from a dehydrogenated sugar polyol derivative of formula (I) or (II).

  本发明涉及一种化妆品用途，即作为筛选紫外线辐射的剂量，使用公式（I）或（II）的糖多醇或去氢糖多醇衍生物所得化合物，其中A1和A2表示紫外线筛选基团；Z1和Z2表示糖多醇基团或去氢糖多醇衍生物，使得公式（I）的产物在其结构中具有1-4个-OH基团和可选的1-2个-COOH基团。本发明还涉及一种组合物，其中包含在化妆品可接受介质中的至少一种公式（I）或（II）的化合物。本发明还涉及由公式（I）或（II）的糖多醇或去氢糖多醇衍生物所得的新化合物。
• [EN] FLAME RETARDANTS FROM RENEWABLE RESOURCES<br/>[FR] IGNIFUGEANTS À PARTIR DE RESSOURCES RENOUVELABLES
  申请人：CENTRAL MICHIGAN UNIVERSITY

  公开号：WO2016022944A1

  公开（公告）日：2016-02-11

  Among other things the invention provides novel flame-retardant compounds useful for increasing the flame retardance of polymers.

  除其他外，该发明提供了新型阻燃化合物，可用于提高聚合物的阻燃性。