thioyl chloride | 14989-32-3

• 分子结构分类: 无机化合物 - 均质非金属化合物 - 其他非金属卤化物
• 英文名称: thioyl chloride
• 英文别名: sulfur monochloride；thiochloride；chlorosulfide；Thiohypochlorous acid
• CAS: 14989-32-3
• 化学式: ClHS
• 分子量: 68.5269
• InChiKey: XDLNRRRJZOJTRW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  2
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  thioyl chloride 、 (+/-)-(2S,4R)-4-methylglutamic acid 以 乙醇 为溶剂， 生成 (2R,4S)-4-Methyl Glutamic Acid Diethyl Ester Hydrochloride
  参考文献：
  名称：

  Esters of alkycarboxy amino acids as prodrugs of modulators of the kainate receptor

  摘要：

  本发明涉及一类丙基羧基氨基酸类谷氨酸类似物的前药化合物，它们作为特异性调节kainate EAA受体阳离子通道的调节剂。这些化合物可用于治疗与离子型EAA受体kainate亚型过度或不足激活相关的神经、神经心理、神经精神、神经退行性、神经精神药理学和功能障碍；治疗与kainate受体去活化、亚最佳激活或过度激活相关的认知障碍；缓解疼痛并改善和增强记忆、学习和相关的心理过程。

  公开号：

  US20020115721A1
• 作为产物：
  描述：

  盐酸 、 硫化氢 生成 thioyl chloride
  参考文献：
  名称：

  Laser‐initiated chemical reactions: Cl+H₂S→HCl+HS: Rate constant, product energy distribution, and direct detection of a chain mechanism

  摘要：

  Laser-initiated, time-resolved infrared chemiluminescence techniques are used to study the detailed kinetics of chlorine/hydrogen sulfide systems. Measurements on the Cl+H2S→HCl+HS reaction are carried out by pulsed laser photolysis of S2Cl2→S2Cl+Cl in a flowing mixture with H2S, while detecting vibrational chemiluminescence from the HCl product. The measured rate constant for the Cl+H2S reaction is 6.0 ±1.2×10−11 cm3 molecule−1 sec−1 at 296°K. The vibrational product distribution is predominately excitation of HCl to v=1 and v=2, with the ratio (v=1):(v=2) =15. The dynamical interpretation of the Cl+H2S reaction data is discussed. Photolysis of Cl2→2Cl in the presence of H2S produces a rapid chain reaction, Cl+H2S→HCl+HS, HS+Cl2→HSCl+Cl. The chain mechanism and its real time development are observed directly from the product chemiluminescence signal.

  DOI：

  10.1063/1.436599
• 作为试剂：
  描述：

  α-chloroethyl benzyl sulfide 在 盐酸 、 thioyl chloride 作用下， 以 溶剂黄146 为溶剂， 反应 1.0h， 以73.3%的产率得到苄磺酰氯
  参考文献：
  名称：

  Baum, James Clayton; Hardstaff, William Rayne; Langler, Richard Francis, Canadian Journal of Chemistry, 1984, vol. 62, p. 1687 - 1691

  摘要：

  DOI：

文献信息

• .alpha.-Cyano-phenoxybenzyl cyclopropane carboxylate insecticides
  申请人：National Research Development Corporation

  公开号：US04000181A1

  公开（公告）日：1976-12-28

  New insecticides are compounds of the formula ##STR1## WHEREIN TWO OF R.sup.1, R.sup.2 and R.sup.3 each represent methyl and the third represents hydrogen, Z represents H, CH.sub.3 --, --CN or --C.tbd.CH, Y represents O or S, Z.sup.1 and Z.sup.2, which may be the same or different, each represent halogen or methyl, and n is 0, 1 or 2.

  新的杀虫剂是具有以下公式的化合物：##STR1## 其中，R.sup.1，R.sup.2和R.sup.3中的两个表示甲基，第三个表示氢，Z表示H，CH.sub.3--，--CN或--C.tbd.CH，Y表示O或S，Z.sup.1和Z.sup.2可能相同也可能不同，每个都表示卤素或甲基，n为0，1或2。
• Laser‐initiated chemical chain reactions
  作者：David J. Nesbitt、Stephen R. Leone

  DOI：10.1063/1.439284

  日期：1980.2

  A detailed kinetic and experimental analysis is presented for chemical chain reaction processes initiated by well-controlled, low power laser pulses. Realtime evolution of the chain reaction is followed by direct detection of infrared chemiluminescence from vibrationally excited HCl product molecules produced by one of the propagation reactions in the chain. By appropriate choice of conditions, the chain reactions may be analyzed separately for pseudofirst-order, radical–reagent processes as well as for second-order, radical–radical events. The pulsed laser initiation technique is applied to three sample chain systems which exhibit distinctly different chain lengths, rates, and termination behaviors. These systems are Cl2/H2S, Cl2/H2, and Cl2/CH3SH. In the case of Cl2/H2S, detailed rate constant data are obtained for the fundamental chain propagation steps, and appropriate chain termination steps are assigned from the observations. The results demonstrate a new, general technique for the quantitative study of chemical chain reactions and related combustion processes.
• US6103729
  申请人：——

  公开号：——

  公开（公告）日：——
• Stock, A.; Wintgen, R., Chemische Berichte, 1920, vol. 53, p. 837 - 842
  作者：Stock, A.、Wintgen, R.

  DOI：——

  日期：——
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: S: SVol.4a/b, 1.3.9.1.4, page 241 - 243
  作者：

  DOI：——

  日期：——