6-Isobornyl-3,4-xylenol | 13741-18-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 6-Isobornyl-3,4-xylenol
• 英文别名: Xibornolum；4,5-dimethyl-2-[(1S,2R,4R)-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]phenol
• CAS: 13741-18-9
• 化学式: C₁₈H₂₆O
• 分子量: 258.404
• InChiKey: RNRHMQWZFJXKLZ-XUWXXGDYSA-N

物化性质

• 熔点：
  94-96°
• 沸点：
  bp3 165-168°; bp9 185-189°
• 密度：
  d420 1.0240

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  19
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Use of xibornol as active agent in the treatment of viral infections
  申请人：ABIOGEN PHARMA S.P.A.

  公开号：US10736856B2

  公开（公告）日：2020-08-11

  The use of xibornol as a virucidal agent is described in the prophylactic or therapeutic treatment of an infection caused by one or more viruses, said viruses comprising at least one of human Adenovirus, human Rhinovirus, human Coronavirus, and a combination thereof.

  西波诺尔作为一种杀病毒剂，用于预防或治疗由一种或多种病毒引起的感染，所述病毒包括人类腺病毒、人类鼻病毒、人类冠状病毒及其组合中的至少一种。
• USE OF XIBORNOL AS ACTIVE AGENT IN THE TREATMENT OF VIRAL INFECTIONS
  申请人：ABIOGEN PHARMA S.P.A.

  公开号：US20190336456A1

  公开（公告）日：2019-11-07

  The use of xibornol as a virucidal agent is described in the prophylactic or therapeutic treatment of an infection caused by one or more viruses, said viruses comprising at least one of human Adenovirus, human Rhinovirus, human Coronavirus, and a combination thereof.
• XIBORNOL FOR USE IN THE TREATMENT OF ACNE VULGARIS
  申请人：ABIOGEN PHARMA S.P.A.

  公开号：US20200155478A1

  公开（公告）日：2020-05-21

  The use of xibornol as an active agent in the treatment of Acne vulgaris is disclosed, said xibornol having shown a remarkable bacteriostatic and bactericidal action on the bacterium mainly responsible of the onset and worsening of Acne vulgaris , i.e. the bacterium Propionibacterium acnes . Pharmaceutical or cosmetic compositions comprising xibornol and suitable pharmaceutically or cosmetically acceptable excipients, for use in the treatment of Acne vulgaris are also disclosed.
• US7790905B2
  申请人：——

  公开号：US7790905B2

  公开（公告）日：2010-09-07
• US7927613B2
  申请人：——

  公开号：US7927613B2

  公开（公告）日：2011-04-19