Fomocaine hydrochloride | 56583-43-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Fomocaine hydrochloride
• 英文别名: Fomocain-hydrochlorid；4-[3-(4-phenoxymethyl-phenyl)-propyl]morpholine hydrochloride；4-[3-(4-phenoxymethyl-phenyl)-propyl]-morpholine; hydrochloride；4-[3-(4-Phenoxymethyl-phenyl)-propyl]-morpholin; Hydrochlorid；Hydron;4-[3-[4-(phenoxymethyl)phenyl]propyl]morpholine;chloride
• CAS: 56583-43-8
• 化学式: C₂₀H₂₅NO₂*ClH
• 分子量: 347.885
• InChiKey: HWDXMCUKRADNLV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.95
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  21.7
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Imidazotriazinone-containing compositions for nasal administration
  申请人：——

  公开号：US20030022894A1

  公开（公告）日：2003-01-30

  The present invention relates to imidazotriazinone-containing compositions for nasal administration which, besides the cGMP PDE inhibitor, contain a small amount of a local anaesthetic.

  本发明涉及用于鼻腔给药的含咪唑三嗪酮的组合物，除了 cGMP PDE 抑制剂外，还含有少量局麻药。
• Antimicotic nail varnish composition
  申请人：——

  公开号：US20040022831A1

  公开（公告）日：2004-02-05

  The present invention relates to a composition comprising a) at least one antimycotic agent and b) at least one film forming agent wherein component b) is a derivative of chitosan selected from hydroxyalkylchitosans and carboxyalkylchitosans and its use as a nail varnish. The present invention is further directed to the use of a water soluble film forming agent selected from hydroxyalkylchitosans and carboxyalkylchitosans as an additive in a nail varnish.

  本发明涉及一种组合物，该组合物包含 a) 至少一种抗霉菌剂和 b) 至少一种成膜剂，其中成分 b) 是壳聚糖的衍生物，该衍生物选自羟基烷基壳聚糖和羧基烷基壳聚糖；本发明还涉及该组合物作为指甲油的用途。本发明进一步涉及选自羟基烷基壳聚糖和羧基烷基壳聚糖的水溶性成膜剂作为指甲油添加剂的用途。
• Compositions for nasal application
  申请人：——

  公开号：US20040142944A1

  公开（公告）日：2004-07-22

  The invention relates to compositions for nasal application containing cGMP-PDE inhibitors, especially PDE5 inhibitors, also containing a small amount of local anaesthetic in addition to said cGMP PDE inhibitor.

  本发明涉及含有 cGMP-PDE 抑制剂（尤其是 PDE5 抑制剂）的鼻腔应用组合物，除上述 cGMP PDE 抑制剂外，还含有少量局麻药。
• Nail restructuring compositions for topical application
  申请人：Mailland Federico

  公开号：US20060134039A1

  公开（公告）日：2006-06-22

  The present invention is directed to compositions containing a combination of a herb from the genus Equisetum together with one film forming agent and its use as a nail topical formulation, like nail varnish, cream, gel, lotion or foam. The present invention is further directed to the use of a water soluble film forming agent as an additive in a nail topical formulation. These compositions can be used to treat specific alterations of the ungula structure, like reduced strength, onychoschizia and ungula brittleness.

  本发明涉及一种组合物，该组合物含有马钱子属草本植物 马钱子 与一种成膜剂的组合物，并将其用作指甲外用制剂，如指甲油、膏霜、凝胶、乳液或泡沫。本发明还涉及一种水溶性成膜剂作为指甲外用制剂添加剂的用途。这些成分可用于治疗甲沟结构的特定改变，如强度降低、甲沟炎和甲沟脆性。
• ANTIMYCOTIC NAIL VARNISH COMPOSITION
  申请人：Polichem S.A.

  公开号：EP1303249A1

  公开（公告）日：2003-04-23