perfluoro(di-n-butylmethylamine) | 514-03-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: perfluoro(di-n-butylmethylamine)
• 英文别名: pefluoro(di-n-butylmethylamine)；perfluoro-N-methyldibutylamine；perfluorodibutylmethylamine；perfluoromethyldibutylamine；F-dibutylmethylamine；bis-nonafluorobutyl-trifluoromethyl-amine；Perfluoro(dibutylmethylamine)；1,1,2,2,3,3,4,4,4-nonafluoro-N-(1,1,2,2,3,3,4,4,4-nonafluorobutyl)-N-(trifluoromethyl)butan-1-amine
• CAS: 514-03-4
• 化学式: C₉F₂₁N
• 分子量: 521.072
• InChiKey: PSJKAILWKIKKNU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  31
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  22

反应信息

• 作为反应物：
  描述：

  perfluoro(di-n-butylmethylamine) 在 五氟化锑 作用下， 反应 0.5h， 生成 全氟(5-氮杂-4-壬烯)
  参考文献：
  名称：

  Splitting of perfluorinated tertiary cyclic amines by the action of SbF5

  摘要：

  It was shown that perfluorinated tertiary cyclic amines are dealkylated by the action of SbF5 with the formation of cyclic azomethines. The presence of a perfluoroalkyl substitutent in the alpha-position to the nitrogen atom in the amine molecule considerably decreases its stability to the action of antimony pentafluoride.

  DOI：

  10.1007/bf00957861
• 作为产物：
  描述：

  苯海拉明 生成 perfluoro(di-n-butylmethylamine)
  参考文献：
  名称：

  Fluorocarbon Nitrogen Compounds. I. Perfluorocarbamic Acid Derivatives, Amides and Oxazolidines¹

  摘要：

  DOI：

  10.1021/ja01602a046

文献信息

• The synthesis of perfluoro (N,N-dialykylcarbamoyl fluorides) by the reaction of perfluoro (N,N-dialkylmethylamines) with oleum
  作者：Takashi Abe、Eiji Hayashi

  DOI：10.1016/s0022-1139(00)84155-x

  日期：1989.11

  A convenient one-step preparation of new perfluoro (N,N-dialkylcarbamoyl fluorides) [dialkyl groups: Rf=R′f=C2F5 (1b); Rf=C2F5, R′f=C3F7 (2b); Rf=R′f=n-C3F7 (3b); Rf=n-C3F7,R′f=n-C4F9 (4b); Rf=n-C3F7,R′f=n-C5F11 (5b); Rf=R′f=n-C4F9 6b; Rf=n-C3F7,R′f=CF3 (7b); Rf=n-C4F9R′=CF3 (8b); Rf=n-C5F11, R′f=CF3 (9b)] is described: the corresponding perfluoro (N,N-dialkylmethylamines) are treated with oleum. Catalysts

  一种方便的一步制备新的全氟（N，N-二烷基氨基甲酰氟）[二烷基：R f = R'f = C 2 F 5（1b）; R f＝ C 2 F 5，R′f＝ C 3 F 7（2b）；ř ˚F = R' ˚F = NC 3 ˚F 7（图3b）; ř ˚F = NC 3 ˚F 7，R' ˚F = NC 4 ˚F 9（图4b）; ř ˚F = NC 3 ˚F 7，R' ˚F = NC 5F 11（5b）；ř ˚F = R' ˚F = NC 4 ˚F 9 6B; ř ˚F = NC 3 ˚F 7，R' ˚F = CF 3（图7b）; R f＝ nC 4 F 9 R′＝ CF 3（8b）；ř ˚F = NC 5 ˚F 11，R' ˚F = CF 3（9B）]中描述了：全氟对应（N，N-dialkylmethylamines）用发烟硫酸处理。催化剂（HgSO 4和MoCl 5）提高了所得产品的收率和纯度。描述
• The electrochemical fluorination of nitrogen-containing carboxylic acids. Fluorination of methyl esters of 3-dialkylamino propionic acids
  作者：Takashi Abe、Eiji Hayashi、Haruhiko Fukaya、Yoshio Hayakawa、Hajime Baba、Shigeki Ishikawa、Kinya Asahino

  DOI：10.1016/s0022-1139(00)82821-3

  日期：1992.4

  Six methyl esters of 3-dialkylamino-substituted propionic acids were subjected to electrochemical fluorination to give the corresponding perfluoroacid fluorides. The following dialkylamino substituents were investigated: diethylamino, di-n-propyl-amino, di-n-butylamino, pyrrolidino, morpholino and piperidino groups. These perfluoroacid fluorides, which were obtained in fair yields, are considered to

  将3-二烷基氨基取代的丙酸的六种甲酯进行电化学氟化，得到相应的全氟代氟化物。研究了以下二烷基氨基取代基：二乙基氨基，二正丙基氨基，二正丁基氨基，吡咯烷基，吗啉代和哌啶子基。这些以合理收率获得的全氟酸氟化物被认为是制备软质（可降解）含氟化合物的潜在关键前体。这些盐在水溶液中显示出明显降低的表面张力。报告了所获得的所有全氟酸氟化物的物理性质，以及它们的光谱数据（19 F NMR，质谱和IR光谱）。
• On the electrochemical fluorination of quaternary ammonium compounds. Part 1. Tetraalkyl ammonium salts
  作者：A. Dimitrov、W. Radeck、St. Rüdiger、O. Bechstein

  DOI：10.1016/s0022-1139(00)82195-8

  日期：1993.1

  Tetraalkylated ammonium compounds, which are known to be very stable towards oxidative attack, can be electrofluorinated readily to yield perfluoro tertiary amines. Other than the enhanced formation of gaseous cleavage products, the electrofluorination proceeds similarly to that of other tertiary amines.

  已知对氧化侵蚀非常稳定的四烷基化铵化合物可以很容易地被电氟化以产生全氟叔胺。除了增强气态裂解产物的形成以外，电氟化的进行过程与其他叔胺类似。
• Method for curing an organic coating using condensation heating and radiant energy
  申请人：MINNESOTA MINING AND MANUFACTURING COMPANY

  公开号：EP0323061A2

  公开（公告）日：1989-07-05

  Coatings are cured by simultaneous exposure to radiant energy and condensing inert perfluoro­chemical vapors. The invention also includes an apparatus for use in curing coatings having a vessel (10) with reservoir (5) filled with inert perfluorochemical liquid (4), heated by heater (2). Cooling coils (13) and (14), for condensing perfluorochemical vapors (6), are located in the inlet (11) and outlet (12) of the vessel (10). A coating (8) on a substrate (7) is carried through the vessel (10) on a continuously moving belt (15). The coating (8) is cured by vapors (6) and radiant energy from energy source (9) passing through windows (16).

  涂层是通过同时暴露于辐射能和冷凝惰性全氟化合物蒸汽而固化的。本发明还包括一种用于固化涂层的设备，该设备具有一个容器（10），容器（10）的储液器（5）中装有惰性全氟化合物液体（4），由加热器（2）加热。冷却线圈（13）和（14）位于容器（10）的入口（11）和出口（12），用于冷凝全氟化合物蒸汽（6）。基材 (7) 上的涂层 (8) 通过连续移动的传送带 (15) 穿过容器 (10)。涂层 (8) 在蒸汽 (6) 和来自能源 (9) 的辐射能作用下通过窗口 (16) 固化。
• Process for rapid thawing and storage of frozen fluorocarbon emulsion, and resultant product
  申请人：ALPHA THERAPEUTIC CORPORATION

  公开号：EP0548601A1

  公开（公告）日：1993-06-30

  A method for rapidly preparing a frozen fluorocarbon emulsion for administration without degradation and having an extended shelf life is disclosed.

  本发明公开了一种快速制备冷冻碳氟化合物乳剂的方法，该乳剂可在不降解的情况下给药，并具有较长的保质期。