Benzo[a]phenazine-5-sulfonic acid | 34276-67-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: Benzo[a]phenazine-5-sulfonic acid
• 英文别名: benzo[a]phenazine-5-sulfonic acid
• CAS: 34276-67-0
• 化学式: C₁₆H₁₀N₂O₃S
• 分子量: 310.3
• InChiKey: ZGCMMXMGYJQSGK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  22
• 可旋转键数：
  1
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  88.5
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• [EN] DETECTION OF TARGET NUCLEIC ACID MOLECULES BY ALTERATION OF REACTION OF A REDOX SPECIES FOLLOWING HYBRIDIZATION WITH IMMOBLIZED CAPTURE NUCLEIC ACID MOLECULES<br/>[FR] DETECTION DE MOLECULES D'ACIDE NUCLEIQUE CIBLES PAR LA MODIFICATION DE LA REACTION D'UNE ESPECE REDOX APRES L'HYBRIDATION AVEC DES MOLECULES D'ACIDE NUCLEIQUE DE CAPTURE IMMOBILISEES
  申请人：UNISEARCH LTD

  公开号：WO2004023128A1

  公开（公告）日：2004-03-18

  The invention relates to an apparatus for the detection of a target nucleic acid molecule, and to methods for making and using the apparatus. The apparatus includes a capture nucleic acid molecule immobilized on a surface, a redox species (e.g. a thiol group (mercaptohexanol), a redox intercalator etc.) and a reaction means (e.g. an electrode) for reaction with the redox species, wherein the capture nucleic acid molecule is capable of (i) moving the redox species and the reaction means into engagement, (ii) displacing the redox species and the reaction means from each other or (iii) permiting a reaction species (such as an ion in solution) to contact the redox species when the capture nucleic acid is hybridised to a target nucleic acid molecule, (i), (ii) or (iii) resulting in an alteration in the reaction of the redox species with the reaction means or the reaction species. The surface optionally includes a plurality of repellent molecules (such as mercaptoethanol, mercaptopropanol, or mercaptohexanol) which limit the adsorption of the capture nucleic acid molecule to the surface and repel suitably charged redox species.
• [EN] LIGHT ACTIVATED ELECTROCHEMISTRY<br/>[FR] ÉLECTROCHIMIE ACTIVÉE PAR LA LUMIÈRE
  申请人：NEWSOUTH INNOVATIONS PTY LTD

  公开号：WO2016037221A1

  公开（公告）日：2016-03-17

  Disclosed herein is a method for performing an electrochemical activity at a localized region of an electrode surface. The method comprises applying light to illuminate a region of a surface of an electrode. The electrode comprises a semiconductor substrate containing covalently bound organic molecules across the semiconductor substrate surface, and an electrochemically active species that is bound to the organic molecules or becomes bound to the organic molecules when a triggering event occurs, wherein the applied light activates the illuminated region of the electrode surface to enable electrochemical activity to occur in that region, through the generation of charge carriers within the semiconductor substrate, which in turn drives an electrochemical activity at the electrochemically active species, with the non-illuminated regions of the electrode surface remaining insulating.