申请人:Piedmont Pharmaceuticals, LLC
公开号:US20030235610A1
公开(公告)日:2003-12-25
The present invention provides compositions of liposomes that contain a biologically active compound and methods of manufacture thereof. Invention methods offer the ability to manufacture liposome compositions containing NSAIDs and other biologically active compounds, and the ability to attain very high encapsulation efficiencies in uniform, stable liposomes. Compositions of liposomes containing anti-viral agents and anti-fungal agents are also provided. Invention liposome compositions are useful for the treatment of a variety of conditions, including, for example, pain and inflammation, bacterial infections and viral infections.
本发明提供了含有生物活性化合物的脂质体组合物及其制造方法。本发明方法提供了制造含有非甾体抗炎药和其他生物活性化合物的脂质体组合物的能力,以及在均匀、稳定的脂质体中实现极高封装效率的能力。本发明还提供了含有抗病毒剂和抗真菌剂的脂质体组合物。本发明的脂质体组合物可用于治疗多种疾病,包括疼痛和炎症、细菌感染和病毒感染等。