bis(2-hydroxy-1-naphthaldehyde) oxaloyldihydrazone | 63968-59-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: bis(2-hydroxy-1-naphthaldehyde) oxaloyldihydrazone
• 英文别名: N,N'-bis[(2-hydroxynaphthalen-1-yl)methylideneamino]oxamide
• CAS: 63968-59-2
• 化学式: C₂₄H₁₈N₄O₄
• 分子量: 426.431
• InChiKey: QWOVWBVVPLQBLH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  32
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  123
• 氢给体数：
  4
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  bis(2-hydroxy-1-naphthaldehyde) oxaloyldihydrazone 、 copper(II) choride dihydrate 以 甲醇 为溶剂， 反应 3.0h， 生成 [Cu3(μ2-Cl)2(bis(2-hydroxy-1-naphthaldehyde) oxaloyldihydrazone(-4H))(H2O)6]*2H2O
  参考文献：
  名称：

  Synthesis and characterization of homotrimetallic copper complexes derived from bis(2-hydroxy-1-naphthaldehyde)oxaloyldihydrazone

  摘要：

  Copper (II) complexes [Cu-3(nph)(mu(2)-X)(2)(H2O)(6)]center dot 2H(2)O [X = CI (1), (CIO4) (3)] and [Cu-3(nph)(NO3)(2)(H2O)(6)] (2) have been synthesized from bis(2-hydroxy-1-naphthaldehyde)oxaloyldihydrazone in methanol medium and characterized. The structures of the complexes have been discussed in the light of data obtained from analytical, thermoanalytical, mass spectral studies, molar conductance, magnetic moment, electronic, EPR, IR, FT-IR spectroscopic studies. The molar conductance values for the complexes fall in the region 0.5-0.9 Sm-2 mol(-1) in DMSO solution indicating that all of them are non-electrolyte. The magnetic moment values for the complexes suggest weak M-M interaction in the structural unit of the complexes. The dihydrazone ligand is present in enol form in all of the complexes. Copper centre has tetragonally distorted octahedral stereochemistry in chlorido and perchlorato complexes while in nitrato complex, copper has mixed square-pyramidal and distorted-octahedral stereochemistry. The EPR parameters of the complexes indicate that the copper centre has the doublet state as the ground state. (c) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2012.07.113
• 作为产物：
  描述：

  乙二酸二酰肼 、 2-羟基-1-萘甲醛 以 乙醇 、 水 为溶剂， 反应 3.0h， 以98%的产率得到bis(2-hydroxy-1-naphthaldehyde) oxaloyldihydrazone
  参考文献：
  名称：

  N,N'-双[2-羟基亚萘基]/[2-甲氧基苯亚甲基]氨基]草酰胺及其二价锰配合物：分离、光谱表征、形态学、抗菌和对白血病细胞的细胞毒性

  摘要：

  摘要 草酸二腙{N,N'-双[2-羟基亚萘基]氨基]草酰胺(BHO)和N,N'-双[2-甲氧基亚苄基]氨基]草酰胺(BMO)}的锰(ii)配合物已通过以下方法合成一种通用的方法论。腙配体（BHO和BMO）通过草酸二酰肼与2-羟基萘-1-甲醛和2-甲氧基苯甲醛缩合获得。从光谱（质量、IR、1H-NMR、UV-Vis、ESR）、磁和热测量以及元素分析 (CHNM) 获得的数据中，已经确定了配体及其配合物的结构。扫描电子显微镜 (SEM) 用于表征复杂表面的形貌。配体以双齿方式与金属中心配位，形成双核 Mn-BHO 和单核 Mn-BMO 配合物。建议锰配合物具有八面体立体化学。已经评估了配体和锰 (ii) 配合物的抗菌和抗白血病活性。与锰 (ii) 离子配位后，游离配体的增殖障碍增强。

  DOI：

  10.1515/chem-2020-0044

文献信息

• Physicochemical studies on some selected oxaloyldihydrazones and their novel palladium(II) complexes along with using oxaloyldihydrazones as corrosion resistants
  作者：Ayman H. Ahmed、A. M. Hassan、Bassem H. Mohamed、Hosni A. Gumaa、Ahmed M. Eraky

  DOI：10.1080/24701556.2017.1357595

  日期：2017.12.2

  New palladium (II) oxaloyldihydrazone complexes are reported and characterized. The mode of bonding as well as the structure of the isolated compounds have been ascertained on the basis of data obtained from elemental analyses (CHNM), spectral (UV-Vis., IR, mass and 1H NMR) and thermal (TG and DTA) measurements. Some optical parameters such as indirect optical band gap and refractive index were estimated

  据报道和表征了新的钯（II）草酰二hydr配合物。已根据元素分析（CHNM），光谱（UV-Vis。，IR，质量和1 H NMR）和热（TG和DTA）获得的数据确定了键合模式以及分离的化合物的结构） 测量。对于分离出的化合物，估计了一些光学参数，例如间接光学带隙和折射率。测试了所有合成的在1 M HCl溶液中对碳钢腐蚀的抑制性能。steel抑制剂在钢表面的吸附过程是自发的一级反应。
• Synthesis, characterization, reactivity, and catalytic studies of heterobimetallic vanadium(V) complexes containing hydrazone ligands
  作者：Arvind Kumar、Sunshine D. Kurbah、Ibanphylla Syiemlieh、Shobha A. Dhanpat、Rosmita Borthakur、Ram A. Lal

  DOI：10.1016/j.ica.2020.120068

  日期：2021.1

  spectra of the complexes showed LMCT bands in addition to intra-ligand π → π* and n → π* transitions. As evident from the cyclic voltammetry, the complexes showed two metal-centred electron transfer reactions [(VVVV(slox)2−/VVVIV(slox)3−] and [(VVVIV(slox)3−/VVVIV(slox)4−]}, in addition to the ligand centred electron transfer reactions. Further, bovine serum albumin (BSA interaction studies of the complexes

  摘要六种杂双金属碱金属双氧钒（V）配位聚合物络合物[M6 VO（μ-O）} 2（μ-OH）4（μ4-slox/ nph）]。n DMF}∞，其中M = Na，K，和Cs; 对于两个二di配体，二水醛基甲醛草酰二hydr（H4slox）和双（2-羟基-1-萘醛）草酰二hydr（H4nph），n（1）为n，（2）-（6）为0。所有配合物已通过各种物理化学技术进行了表征，例如元素分析，摩尔电导，IR，NMR，UV-vis和循环伏安法。IR，1 HNMR和13 C NMR光谱数据表明，二hydr酮通过酚盐/萘甲酸氧，烯醇氧和嗪氮原子配位至金属中心。Na6 VO（μ-O）} 2（μ-OH）4（μ4-slox）]。DMF}∞（1）的结构也由单晶X射线数据确定，这表明H4slox通过所有可能的配位部位与金属中心配成四元八齿配位体。钒金属中心采用扭曲的方金字塔形配位几何形状，钠原子也处于五个配位
• Synthesis and characterization of [Mn(phen)(H 2 O) 4 ]·SO 4 ·2H 2 O
  作者：Ibanphylla Syiemlieh、Arvind Kumar、Sunshine D. Kurbah、Ram A. Lal

  DOI：10.1016/j.molstruc.2018.04.027

  日期：2018.8

  Abstract Manganese(II) complex [Mn(phen)(H2O)4]·SO4·2H2O has been synthesized in aqueous methanol medium. The complex crystal was directly obtained from reaction of MnSO4·H2O in water with a mixture of methanol solution of disalicyaldehyde oxaloyldihydrazone and 1,10-phenanthroline. Its structure has been established by X-ray crystallography. It has also been characterized by thermogravimetry, TEM

  摘要 在甲醇水溶液中合成了锰(II)配合物[Mn(phen)(H2O)4]·SO4·2 。由MnSO4· 在水中与二水杨醛草酰二腙和1,10-菲咯啉的甲醇溶液反应直接得到配合物晶体。其结构已通过 X 射线晶体学确定。它还通过热重分析、TEM、磁矩、紫外-可见光、EPR 和红外光谱进行表征。由于 6A1g (F)→ 4T2g (G) 跃迁和强电荷转移带，该配合物是正常顺磁性的，并且在 420 nm 处显示出弱的 dd 带。配合物的 EPR 谱表明金属-金属相互作用随着温度的降低而减少。该配合物的红外光谱与 1,10-菲咯啉与锰 (II) 中心的配位一致。
• Synthesis, characterization and structure assessment of mononuclear and binuclear low-spin manganese(II) complexes derived from oxaloyldihydrazones, 1,10-phenanthroline and 2,2′-bipyridine
  作者：Ibanphylla Syiemlieh、Arvind Kumar、Sunshine D. Kurbah、Ram A. Lal

  DOI：10.1016/j.molstruc.2018.04.043

  日期：2018.8

  studies, the structures of the complexes have been established. From molar conductance it is suggested that all the complexes are non-electrolyte in DMF medium. The complex (2a) is monomeric in nature whereas the complexes (1) to (4) are dimeric based on the molecular weight data. The effective magnetic moment of complexes (1) to (4) show metal-metal interaction while complex (2a) has no metal-metal interaction

  摘要 低自旋锰 (II) 配合物 [Mn II (H 2 slox) (bipy)] (1), [Mn II (H 2 slox) (phen)] (2), [Mn II (H 2 slox) ( phen)].1.5.H 2 O (2a)、[Mn II (H 2 nph) (bipy)].H 2 O (3) 和 [Mn II (H 2 nph) (phen)].H 2 O ( 4) 在甲醇-水介质中由草酰二腙合成。通过分析、分子量和热分析数据确定复合物的化学计量。基于从摩尔电导、紫外-可见、红外光谱、磁矩和电子顺磁共振光谱研究中获得的数据，已经建立了配合物的结构。从摩尔电导表明，所有配合物在 DMF 介质中都是非电解质。根据分子量数据，配合物(2a)本质上是单体，而配合物(1)至(4)是二聚体。配合物（1）至（4）的有效磁矩表现出金属-金属相互作用，而配合物（2a）没有金属-金属相互作用。配合物
• Bovine serum albumin–vanadium complex hybrid: Synthesis, crystal structure, SOD activities and asymmetric catalytic oxidation of sulfides
  作者：Jingnan Shi、Yi Wei、Yuzhen Zhang、Jie Tang、Hedong Bian、Qing Yu、Fuping Huang

  DOI：10.1016/j.poly.2019.01.050

  日期：2019.4

  the ABTS method. The results indicate that the activity of hybrid protein was more pronounced than that of the corresponding complex. At the same time, the hybrid protein can catalyze asymmetric oxidation of methyl phenyl sulfide.

  摘要分别通过水杨醛和2-羟基-1-萘醛与草酰二肼的缩合反应合成了两个对称的席夫碱对称配体H4L1和H4L2。通过单晶X射线衍射分析了它们的钒配合物的晶体结构。通过各种光谱方法研究了合成配合物与BSA之间的相互作用。结合参数包括猝灭常数KSV，结合常数K和结合模式。研究表明，淬火类型是由络合物形成引起的静态淬火过程。用黄嘌呤氧化酶-NBT还原法测定复合物的SOD活性。通过ABTS方法测定复合物的抗氧化能力。结果表明，杂合蛋白的活性比相应复合物的活性更显着。同时，杂合蛋白可以催化甲基苯基硫化物的不对称氧化。