2-(phenylselanyl)ethanamine hydrochloride | 106929-79-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(phenylselanyl)ethanamine hydrochloride
• 英文别名: 2-(phenylselanyl)ethylamine hydrochloride；2-phenylselenenylethylamine hydrochloride；2-(phenylseleno)ethylamine hydrochloride；2-Phenylselanylethanamine;hydrochloride
• CAS: 106929-79-7
• 化学式: C₈H₁₁NSe*ClH
• 分子量: 236.603
• InChiKey: FPPMWZBBBUYZBY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.81
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  26
• 氢给体数：
  2
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  2-(phenylselanyl)ethanamine hydrochloride 在 potassium hydroxide 作用下， 以 乙醇 为溶剂， 生成 苯基-2-氨基乙基硒醚
  参考文献：
  名称：

  Novel copper(II) and cobalt(II) complexes with selenium substituted imidazolyl imines. The molecular and crystal structure of [N-(2-(phenylseleno)ethyl)-N-(imidazol-2-ylmethylene)amine]copper(II) dichloride

  摘要：

  A series of copper(II) and cobalt(II) complexes with novel selenium containing Schiff base ligands obtained from 2- or 3-aminoalkyl phenyl selenides and imidazole carbaldehydes have been synthesized by the interaction of corresponding organic ligands with MCl2 center dot 6H(2)O (M = Cu, Co). The crystal structure of a copper(II) complex with N-(2-(phenylseleno)ethyl)-N-(imidazolyl-2-ylmethylene)amine has been solved by a single-crystal X-ray diffraction method. The copper(II) ions are coordinated by the imine and imidazole nitrogen atoms of organic ligands and two chloride anions in a distorted square planar geometry. The electrochemical investigations of the synthesized ligands and complexes have been made by cyclic voltammetry method. It is established that the first stage of complexes reduction takes place to metal and the reduced forms of complexes are stable in the solution. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2012.11.039
• 作为产物：
  描述：

  N-(2-phenylselanylethyl)acetamide 生成 2-(phenylselanyl)ethanamine hydrochloride
  参考文献：
  名称：

  MAY, S. W.;HERMAN, H. H.;ROBERTS, S. F.

  摘要：

  DOI：

文献信息

• Terminal Organylchalcogenoethyl- and -propylamines and Their Schiff Base Derivatives
  作者：Svetlana V. Amosova、Natalia A. Makhaeva、Alexander V. Martynov、Vladimir A. Potapov、Barry R. Steele、Ioannis D. Kostas

  DOI：10.1055/s-2005-865310

  日期：——

  A series of organoselanyl- and organotellanyl-substituted ethyl- and propylamines and their hydrochlorides, as well as 2-(methylsulfanyl)ethylamine have been synthesized. Efficient general synthetic routes have been developed to chalcogen(S, Se, Te)-containing Schiff bases with di- and trimethylene bridges between the nitrogen atom of the imino group and the chalcogen, by condensation of 3-(tert-butyl)- and 3-(1-ethylpropyl)-2-hydoxybenzene-carbaldehydes with the amines. The influence of the organylchalcogenyl-group on some spectral characteristics (1H, 13C, 77Se NMR spectroscopy) of both amines and Schiff bases is discussed.

  我们合成了一系列有机硒基和有机噻吩基取代的乙胺和丙胺及其盐酸盐，以及 2-（甲硫基）乙胺。通过 3-(tert-butyl)- 和 3-(1-ethylpropyl)-2-hydoxybenzene-carbaldehydes 与胺的缩合，开发出了含查尔根（S、Se、Te）的希夫碱的高效通用合成路线，在亚氨基的氮原子和查尔根之间具有二亚甲基和三亚甲基桥。本文讨论了醛基对胺和席夫碱的一些光谱特性（1H、13C、77Se NMR 光谱）的影响。
• 3a-(o-Nitrophenyl)octahydroindol-4-ones: Synthesis and spectroscopic analysis
  作者：Daniel Solé、Joan Bosch、Josep Bonjoch

  DOI：10.1016/s0040-4020(96)00065-8

  日期：1996.3

  A short entry to 3a-(o-nitrophenyl)octahydroindol-4-ones employing ozonolysis and double reductive amination of 2-allyl-2-(o-nitrophenyl)-1,3-cyclohexanedione (9) is described. The symmetric dione 9 is synthesized in a 50% overall yield from 1,3-cyclohexanedione by means of o-nitroarylation followed by O-allylation and subsequent Claisen rearrangement. Configurational and conformational aspects of azabicyclic derivatives 1 (a-k) are discussed.
• cis-3a-(o-Nitrophenyl)octahydroindol-4-one. building blocks for the synthesis of indole alkaloids
  作者：Daniel Solé、Josep Bonjoch

  DOI：10.1016/s0040-4039(00)93461-0

  日期：1991.9

  A four-step synthesis of 3a-aryloctahydroindol-4-ones (1) in which the key step is the ozonolysis of 2-allyl-2-(omicron-nitropheyl)-1,3-cyclohexanedione (5) followed by reductive aminocyclization has been accomplished. An asymmetric synthesis of the bicyclic system 1 from chiral amines is achieved by means of this procedure.
• New sulfanyl- and selanyl-substituted Schiff bases derived from 2-chalcogenoalkylamines and aromatic aldehydes. Synthesis and complex formation reactions
  作者：A. N. Chernysheva、E. K. Beloglazkina、R. L. Antipin、A. A. Moiseeva、N. V. Zyk

  DOI：10.1134/s1070363213020138

  日期：2013.2

  A number of beta-phenyl(or benzyl)selanyl- and beta-phenylsulfanyl-substituted imines possessing an additional donor nitrogen, oxygen, or sulfur atom were synthesized by reaction of 2-phenylsulfanylethanamine, 2-phenylsulfanylcyclohexanamine, 2-phenylselanylcyclohexanamine, and 2-benzylselanylaniline with salicylaldehyde, 2-pyridinecarbaldehyde, or 2-tert-butylsulfanylbenzaldehyde. The resulting Schiff bases were tested as ligands in the complex formation with nickel(II) and copper(II), and mononuclear (L-H)MCl or LMCl2 coordination compounds were isolated (L = sulfur- or selenium-containing imine). The redox properties of the selenium-containing ligands and complexes were studied by cyclic voltammetry. The complexes were found to undergo reduction of the metal ion in two one-electron steps. The reduction is reversible for copper complexes and irreversible for nickel complexes. DOI: 10.1134/S1070363213020138
• Novel copper(II) and cobalt(II) complexes with selenium substituted imidazolyl imines. The molecular and crystal structure of [N-(2-(phenylseleno)ethyl)-N-(imidazol-2-ylmethylene)amine]copper(II) dichloride
  作者：Elena K. Beloglazkina、Alexander G. Majouga、Roman L. Antipin、Kseniya A. Myannik、Anna A. Moiseeva、Nikolai V. Zyk

  DOI：10.1016/j.poly.2012.11.039

  日期：2013.2

  A series of copper(II) and cobalt(II) complexes with novel selenium containing Schiff base ligands obtained from 2- or 3-aminoalkyl phenyl selenides and imidazole carbaldehydes have been synthesized by the interaction of corresponding organic ligands with MCl2 center dot 6H(2)O (M = Cu, Co). The crystal structure of a copper(II) complex with N-(2-(phenylseleno)ethyl)-N-(imidazolyl-2-ylmethylene)amine has been solved by a single-crystal X-ray diffraction method. The copper(II) ions are coordinated by the imine and imidazole nitrogen atoms of organic ligands and two chloride anions in a distorted square planar geometry. The electrochemical investigations of the synthesized ligands and complexes have been made by cyclic voltammetry method. It is established that the first stage of complexes reduction takes place to metal and the reduced forms of complexes are stable in the solution. (C) 2012 Elsevier Ltd. All rights reserved.