2,2,2-Trichlor-1,1-bis-trimethylsilyloxy-ethan | 18279-99-7

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: 2,2,2-Trichlor-1,1-bis-trimethylsilyloxy-ethan
• 英文别名: 2,2,6,6-tetramethyl-4-trichloromethyl-3,5-dioxa-2,6-disila-heptane；2,2,6,6-Tetramethyl-4-trichlormethyl-3,5-dioxa-2,6-disila-heptan；1,1,1-Trichlor-2,2-bis-trimethylsilyloxy-aethan；trimethyl-(2,2,2-trichloro-1-trimethylsilyloxyethoxy)silane
• CAS: 18279-99-7
• 化学式: C₈H₁₉Cl₃O₂Si₂
• 分子量: 309.768
• InChiKey: ZPTHTPBARHYKJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.39
• 重原子数：
  15.0
• 可旋转键数：
  4.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.46
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  2,2,2-Trichlor-1,1-bis-trimethylsilyloxy-ethan 在 iodine pentafluoride 作用下， 以 乙腈 为溶剂， 生成 三甲基氟硅烷 、 三氯乙醛 、 alkaline earth salt of/the/ methylsulfuric acid
  参考文献：
  名称：

  Beiträge zur chemie des iodpentafluorids teil II. Iod(V)-verbindungen mit α,ω-difunktionellen alkoholaten

  摘要：

  DOI：

  10.1016/s0022-1139(00)80926-4
• 作为产物：
  描述：

  三甲基氯硅烷 、 水合氯醛 生成 2,2,2-Trichlor-1,1-bis-trimethylsilyloxy-ethan
  参考文献：
  名称：

  观察条件对根尖周炎放射学诊断的影响

  摘要：

  Objectives To determine the effect of viewing conditions upon diagnosis of early periapical inflammatory pathosis on intra-oral radiographs, and to examine the effect of observer experience upon diagnostic performance in this task.Methods 50 observers examined 18 periapical radiographs using three different viewing conditions (room lighting; viewing box; viewing box with x2 magnification and masking). Their diagnoses were compared with an 'expert' diagnosis provided by repeated viewings of the films by two dental radiologists. Sensitivities and specificities were determined.Results When 'ideal' viewing conditions were used, optimal sensitivity (78%) and specificity (78%) were obtained. Use of a viewing box was associated with significantly higher specificity than the use of room lighting (P = 0.0016). Use of masking and x2 magnification was associated with significantly higher sensitivity than a viewing box alone (P = 0.004). There were few significant differences in diagnostic performance between observers, but qualified dental staff had significantly higher specificities than 4th year (P = 0.01) and 5th year (P = 0.01) students when a viewing box was used alone.Conclusions This study on early periapical inflammatory pathosis gives support to guidelines which recommend the use of a viewing box, x2 magnification and masking for interpreting intra-oral radiographs. It also suggests that observer experience may influence interpretation of early periapical pathosis.

  DOI：

  10.1038/sj.bdj.4800596a

文献信息

• Shikhiev,I.A. et al., Journal of general chemistry of the USSR, 1962, vol. 32, p. 1628 - 1629
  作者：Shikhiev,I.A. et al.

  DOI：——

  日期：——
• Beiträge zur chemie des iodpentafluorids teil II. Iod(V)-verbindungen mit α,ω-difunktionellen alkoholaten
  作者：Hermann Josef Frohn、Wolfgang Pahlmann

  DOI：10.1016/s0022-1139(00)80926-4

  日期：1984.10
• The influence of viewing conditions on radiological diagnosis of periapical inflammation
  作者：N. Patel、V. Rushton、T. Macfarlane、K. Horner

  DOI：10.1038/sj.bdj.4800596a

  日期：2000.7.8

  Objectives To determine the effect of viewing conditions upon diagnosis of early periapical inflammatory pathosis on intra-oral radiographs, and to examine the effect of observer experience upon diagnostic performance in this task.Methods 50 observers examined 18 periapical radiographs using three different viewing conditions (room lighting; viewing box; viewing box with x2 magnification and masking). Their diagnoses were compared with an 'expert' diagnosis provided by repeated viewings of the films by two dental radiologists. Sensitivities and specificities were determined.Results When 'ideal' viewing conditions were used, optimal sensitivity (78%) and specificity (78%) were obtained. Use of a viewing box was associated with significantly higher specificity than the use of room lighting (P = 0.0016). Use of masking and x2 magnification was associated with significantly higher sensitivity than a viewing box alone (P = 0.004). There were few significant differences in diagnostic performance between observers, but qualified dental staff had significantly higher specificities than 4th year (P = 0.01) and 5th year (P = 0.01) students when a viewing box was used alone.Conclusions This study on early periapical inflammatory pathosis gives support to guidelines which recommend the use of a viewing box, x2 magnification and masking for interpreting intra-oral radiographs. It also suggests that observer experience may influence interpretation of early periapical pathosis.