4-Bromo-3-methoxynaphthalene-2-carboxylic acid | 201416-09-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 4-Bromo-3-methoxynaphthalene-2-carboxylic acid
• CAS: 201416-09-3
• 化学式: C₁₂H₉BrO₃
• mdl: MFCD00196847
• 分子量: 281.106
• InChiKey: NGGAKJLGWWORCT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-Bromo-3-methoxynaphthalene-2-carboxylic acid 在 2-双环己基膦-2',6'-二甲氧基联苯 、 bis(1,5-cyclooctadiene)nickel (0) 、 potassium phosphate 、 1,1,3,3-四甲基二硅氧烷 、 硫酸 、 palladium diacetate 、 三环己基膦 作用下， 以 甲苯 为溶剂， 反应 24.0h， 生成 methyl 4-phenyl-2-naphthoate
  参考文献：
  名称：

  Ni-Catalyzed Reduction of Inert C−O Bonds: A New Strategy for Using Aryl Ethers as Easily Removable Directing Groups

  摘要：

  An efficient Ni-catalyzed protocol for the reductive cleavage of inert C-O bonds has been developed. The method is characterized by its simplicity and wide scope, thereby allowing the use of aryl ethers as easily removable directing groups in organic synthesis.

  DOI：

  10.1021/ja106943q
• 作为产物：
  描述：

  2-羟基-3-萘甲酸 在 溴 、 potassium carbonate 作用下， 以 1,4-二氧六环 为溶剂， 生成 4-Bromo-3-methoxynaphthalene-2-carboxylic acid
  参考文献：
  名称：

  Ni-Catalyzed Reduction of Inert C−O Bonds: A New Strategy for Using Aryl Ethers as Easily Removable Directing Groups

  摘要：

  An efficient Ni-catalyzed protocol for the reductive cleavage of inert C-O bonds has been developed. The method is characterized by its simplicity and wide scope, thereby allowing the use of aryl ethers as easily removable directing groups in organic synthesis.

  DOI：

  10.1021/ja106943q

文献信息

• COMPOSITION FOR FORMING ANTIREFLECTION FILM FOR LITHOGRAPHY
  申请人：Nissan Chemical Industries, Ltd.

  公开号：EP1560070A1

  公开（公告）日：2005-08-03

  There is provided a composition for forming anti-reflective coating for anti-reflective coating that has a good absorption of light at a wavelength utilized for manufacturing a semiconductor device, that exerts a high protection effect against light reflection, that has a high dry etching rate compared with the photoresist layer. Concretely, the composition for forming anti-reflective coating contains a triazine trione compound, oligomer compound or polymer compound having hydroxyalkyl structure as substituent on nitrogen atom.

  本发明提供了一种用于形成防反射涂层的组合物，该组合物对用于制造半导体器件的波长的光具有良好的吸收性，对光的反射具有较高的保护效果，与光刻胶层相比具有较高的干蚀刻率。具体来说，用于形成抗反射涂层的组合物含有一种三嗪三酮化合物、低聚物化合物或聚合物化合物，其氮原子上的取代基为羟烷基结构。
• SALTS OF PAROXETINE
  申请人：SMITHKLINE BEECHAM PLC

  公开号：EP1091958A1

  公开（公告）日：2001-04-18
• US7425399B2
  申请人：——

  公开号：US7425399B2

  公开（公告）日：2008-09-16
• [EN] SALTS OF PAROXETINE<br/>[FR] SELS DE PAROXETINE
  申请人：SMITHKLINE BEECHAM PLC

  公开号：WO2000001692A1

  公开（公告）日：2000-01-13

  Piperidine compounds, processes for preparing them, pharmaceutical compositions comprising them and their use in therapy are disclosed.
• Ni-Catalyzed Reduction of Inert C−O Bonds: A New Strategy for Using Aryl Ethers as Easily Removable Directing Groups
  作者：Paula Álvarez-Bercedo、Ruben Martin

  DOI：10.1021/ja106943q

  日期：2010.12.15

  An efficient Ni-catalyzed protocol for the reductive cleavage of inert C-O bonds has been developed. The method is characterized by its simplicity and wide scope, thereby allowing the use of aryl ethers as easily removable directing groups in organic synthesis.