perfluoro-di-(1-methyl-butyl)ether | 92978-08-0

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 有机氟化物
• 英文名称: perfluoro-di-(1-methyl-butyl)ether
• 英文别名: 1,1,1,2,2,3,3,4,5,5,5-Undecafluoro-4-(1,1,1,2,3,3,4,4,5,5,5-undecafluoropentan-2-yloxy)pentane
• CAS: 92978-08-0
• 化学式: C₁₀F₂₂O
• 分子量: 554.074
• InChiKey: TWKUPTMUBKZFFA-UHFFFAOYSA-N

物化性质

• 沸点：
  136 °C
• 密度：
  1.729±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.9
• 重原子数：
  33
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  23

反应信息

• 作为产物：
  描述：

  bis-(2,2,3,4,4,4-hexafluoro-1-methylbutyl) ether 在 cobalt (III) fluoride 作用下， 以41%的产率得到perfluoro-di-(1-methyl-butyl)ether
  参考文献：
  名称：

  全氟醚的新途径

  摘要：

  通过在非常高的温度下使用三氟化钴将通过将醚基自由基加成到全氟烯烃或-环烯烃上而得到的部分氟化醚转化为全氟醚。

  DOI：

  10.1016/s0022-1139(00)81484-0

文献信息

• Method and apparatus for transforming chemical fluids using halogen or oxygen in a photo-treatment process
  申请人：Tarancon Gregorio

  公开号：US20050087434A1

  公开（公告）日：2005-04-28

  A method of treatment of reactant fluids such as hydrochlorofluorocarbons (HCFCs), hydrofluorocarbons (HFCs), hydrochlorocarbons (HCCs), and hydrocarbons (HCs) for the production of new chemical fluids. Another method of treatment for the transformation of the reactant fluids having impurities present in the chlorofluorocarbons (CFCs) or fluorocarbons (FCs) for yielding a high quality chemical product. Reactant fluids with impurities present in used CFC or FC may form an azeotropic mixture. A photochemical reaction is used wherein the reactant fluids are molecules with hydrogen atoms in a hydrogen-carbon bond. The process is comprised of the following steps: placing the reactant fluids into a process compartment of the photochemical reactor; placing halogen fluid or oxygen fluid into the process compartment of the photochemical reactor, wherein the halogen fluid is selected from a group consisting of chlorine (Cl 2 ), bromine (Br 2 ) and iodine (I 2 ); and irradiating the fluids and the halogen or oxygen fluid using radiant energy from lamps operating in the visible and ultraviolet light regions of the electromagnetic spectrum to conduct thermolysis, photolysis and photochemical treatment by halogenating or oxidizing the molecules of the reactant fluids with the halogen or oxygen fluids to form halogenated or oxidized fluids during a dwell time period.

  一种处理反应流体，如氢氯氟烃（HCFCs）、氢氟烃（HFCs）、氢氯烃（HCCs）和碳氢化合物（HCs）以生产新的化学流体的方法。另一种处理含有氯氟烃（CFCs）或氟烃（FCs）中存在的杂质的反应流体以产生高质量化学产品的方法。在使用的CFC或FC中存在的杂质的反应流体可能形成共沸混合物。所使用的是光化学反应，其中反应流体是氢原子在氢碳键中的分子。该过程包括以下步骤：将反应流体放入光化学反应器的处理室中；将卤素流体或氧气流体放入光化学反应器的处理室中，其中卤素流体选自由氯（Cl2）、溴（Br2）和碘（I2）组成的组；并且使用在电磁频谱的可见光和紫外光区域运行的灯的辐射能照射流体和卤素或氧气流体，以进行热解、光解和通过卤素化或氧化卤素或氧气流体中的反应流体分子进行光化学处理，在停留时间期间形成卤素化或氧化流体。
• Free radical chemistry. Part 5. [1] A new approach to the synthesis of perfluorinated ethers
  作者：Richard D. Chambers、Brian Grievson、Frederick G. Drakesmith、Richard L. Powell

  DOI：10.1016/s0022-1139(00)82331-3

  日期：1985.9

  Fluorinations of the free-radical adducts of fluorinated alkenes, to ethers, over cobalt trifluoride are described and perfluorinated ethers are obtained at temperatures in excess of 400°C. The effect of structure on the formation of perfluoroethers is outlined.

  描述了在三氟化钴上氟化烯烃的自由基加合物向醚的氟化，并且在超过400°C的温度下获得了全氟化醚。概述了结构对全氟醚形成的影响。
• Free-radical chemistry. Part 8[1]. Electrochemical fluorination of partly fluorinated ethers
  作者：Richard D. Chambers、Robert W. Fuss、Michael Jones、Peter Sartori、Alan P. Swales、Ralf Herkelmann

  DOI：10.1016/s0022-1139(00)85035-6

  日期：1990.9

  Free-radical additions of hexafluoropropene to cyclic ethers may be carried out to achieve mono- or di-adducts and mixtures of isomers of di-adducts are formed. These adducts may be fluorinated, using electrochemical fluorination, to give the corresponding perfluoro-ethers and, in some cases, with surprising efficiency. Adducts of acyclic ethers are less efficiently fluorinated.

  可以将六氟丙烯自由基加成到环醚上，以获得单加合物或二加合物，并形成二加合物的异构体的混合物。可以使用电化学氟化法将这些加合物氟化，得到相应的全氟醚，在某些情况下，其效率出乎意料。无环醚的加合物氟化效率较低。
• Thermal preactivation of gaseous precursor filled compositions
  申请人：IMARX PHARMACEUTICAL CORP.

  公开号：EP0901793A1

  公开（公告）日：1999-03-17

  The present invention describes, among other things, the surprising discovery that gaseous precursor filled compositions are profoundly more effective as acoustically active contrast agents when they are thermally preactivated to temperatures at or above the boiling point of the instilled gaseous precursor prior to their in vivo administration to a patient. Further optimization of contrast enhancement is achieved by administering the gaseous precursor filled compositions to a patient as an infusion. Enhanced effectiveness is also achieved for ultrasound mediated targeting and drug delivery.

  本发明描述了，除其他外，令人惊奇的发现，如果在对患者进行体内给药之前，将充满气态前体的组合物进行热预活化，使其温度达到或超过灌注气态前体的沸点，那么这些组合物作为声学活性造影剂的效果就会大大提高。通过向患者输注充满气态前体的组合物，可进一步优化造影剂的增强效果。此外，还能提高超声波介导的靶向和药物输送的效果。
• PROCESSES FOR THE RECOVERY AND RECYCLING OF BORON TRIFLUORIDE OR COMPLEXES THEREOF
  申请人：Idemitsu Kosan Co., Ltd.

  公开号：EP1557221A1

  公开（公告）日：2005-07-27

  The invention provides processes for the recovery of a catalyst which are to be applied to the reactions wherein boron trifluoride or a complex thereof is used as the catalyst, that is, (I) a process for the recovery of a catalyst which comprises using as the reaction solvent a solvent containing a hydrofluorocarbon compound and/or an oxygenic hydrofluorocarbon compound and, after the completion of the reaction, separating the reaction solvent from the reaction mixture; and (II) a process for the recovery of a catalyst which comprises extracting boron trifluoride or a complex thereof from the reaction mixture after the completion of the reaction by using a hydro fluorocarbon compound and/or an oxygenic hydrofluorocarbon compound as the extracting solvent. According to the processes, boron trifluoride or complexes thereof used as catalyst can be easily separated from the reaction mixtures and re-used.

  本发明提供的催化剂回收工艺适用于以三氟化硼或其络合物为催化剂的反应，即 (I) 一种催化剂回收工艺，包括使用含有氢氟碳化合物和/或含氧氢氟碳化合物的溶剂作为反应溶剂，并在反应完成后将反应溶剂从反应混合物中分离出来；以及 (II) 一种催化剂回收工艺，包括在反应完成后使用氢氟碳化合物和/或含氧氢氟碳化合物从反应混合物中提取三氟化硼或其络合物；(II) 一种催化剂回收工艺，该工艺包括在反应完成后，使用氢氟碳化合物和/或含 氧氢氟碳化合物作为萃取溶剂，从反应混合物中萃取三氟化硼或其络合物。根据这些工艺，用作催化剂的三氟化硼或其络合物可以很容易地从反应混合物中分离出来并重复使用。