1,6-diamino-2-methoxynaphthalene | 1392006-63-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1,6-diamino-2-methoxynaphthalene
• 英文别名: 2-Methoxynaphthalene-1,6-diamine
• CAS: 1392006-63-1
• 化学式: C₁₁H₁₂N₂O
• 分子量: 188.229
• InChiKey: VZHQEWGGTGUQJI-UHFFFAOYSA-N

物化性质

• 沸点：
  406.6±30.0 °C(Predicted)
• 密度：
  1.237±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  14
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.09
• 拓扑面积：
  61.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1,6-二溴-2-甲氧基萘 在 C₂₄H₁₂Cu₂F₉N₄O₇ 、 四丁基溴化铵 、 氨 、 caesium carbonate 作用下， 以 水 为溶剂， 反应 16.0h， 以100%的产率得到1,6-diamino-2-methoxynaphthalene
  参考文献：
  名称：

  Diamination of Phenylene Dihalides Catalyzed by a Dicopper Complex

  摘要：

  Diamination of phenylene dihalides with aqueous ammonia to give the corresponding phenylenediamines can be achieved by using a dicopper complex [Cu-2(bpnp)(OH)(CF3COO)(3)] (1) (bpnp = 2,7-bis(pyridine-2-yl)-1,8-naphthyridine) as the catalyst in the presence of Bu4NBr and Cs2CO3 in high yields. In addition, 1,3,5-tribromobenzene was converted into benzenetriamine quantitatively under the same conditions. This method offers a new opportunity, particularly simplifying steps and increasing yields, for the preparation of aryl diamines.

  DOI：

  10.1021/jo301244p

文献信息

• Diamination of Phenylene Dihalides Catalyzed by a Dicopper Complex
  作者：Bei-Sih Liao、Shiuh-Tzung Liu

  DOI：10.1021/jo301244p

  日期：2012.8.3

  Diamination of phenylene dihalides with aqueous ammonia to give the corresponding phenylenediamines can be achieved by using a dicopper complex [Cu-2(bpnp)(OH)(CF3COO)(3)] (1) (bpnp = 2,7-bis(pyridine-2-yl)-1,8-naphthyridine) as the catalyst in the presence of Bu4NBr and Cs2CO3 in high yields. In addition, 1,3,5-tribromobenzene was converted into benzenetriamine quantitatively under the same conditions. This method offers a new opportunity, particularly simplifying steps and increasing yields, for the preparation of aryl diamines.