choline succinate | 109438-15-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: choline succinate
• 英文别名: choline succinate salt；dicholine succinate；bis[2-hydroxyethyl-N,N,N-trimethylaminium] butanedioate；Butanedioate;2-hydroxyethyl(trimethyl)azanium；butanedioate;2-hydroxyethyl(trimethyl)azanium
• CAS: 109438-15-5
• 化学式: C₄H₄O₄*2C₅H₁₄NO
• 分子量: 324.418
• InChiKey: LXMXJLNOLAGNQG-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -3.05
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  101
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  丁二酸 、 氯化胆碱 在 anion exchange resin Ambersep 900 OH 作用下， 以 水 为溶剂， 生成 choline succinate
  参考文献：
  名称：

  木质素溶解的高效可持续溶剂：胆碱羧酸盐水溶液

  摘要：

  木质素是有前途的化石资源替代品，可用于生产燃料，生物复合材料和增值化学品。为了更好地利用这种自然资源，仍然有必要开发有效的木质素溶剂。因此，在这项工作中，通过向生物来源的胆碱羧酸盐离子液体（ILs）中添加水，已经开发出13种新型木质素溶剂。木质素的溶解度已在25°C下确定为IL含量的函数。系统检查了ILs的阴离子结构对木质素溶解度的影响。发现在这些溶剂中，六种类型的IL在室温下显示出木质素溶解的高效能力。木质素在羧酸根阴离子中的溶解度随烷基链长度的增加而增加，2组以及使用胆碱二-/三羧酸盐会导致木质素溶解度降低，甚至使木质素不溶于溶剂。根据NMR测量，这些结果已通过阴离子羧基的强水合以及阴离子和阳离子的烷基链与木质素的可能相互作用来解释。另外，溶解的木质素可以通过添加额外的水来再生，并且在溶解和再生过程中不会发生化学反应。

  DOI：

  10.1039/c7gc01886j

文献信息

• COSMETIC INGREDIENT, COSMETIC, AND PRODUCTION METHOD FOR COSMETIC
  申请人：Miyoshi Oil & Fat Co., Ltd.

  公开号：EP3925671A1

  公开（公告）日：2021-12-22

  Provided are a novel cosmetic compounding agent capable of imparting superior properties such as a water and moisture retention property to a cosmetic for use on the hair and skin; a cosmetic using the cosmetic compounding agent; and a method for producing the cosmetic. The cosmetic compounding agent of the present invention contains an organic ammonium salt having a hydrogen-bonding functional group(s) in a cation and/or an anion. In a preferable embodiment, the cation is an ammonium cations represented by the following formula (I):         N+[R1]n[R2]4-n     (I) wherein each R1 independently represents, for example, a hydroxyalkyl group in which there is at least one hydroxy group, an alkyl moiety is a linear or branched moiety having 1 to 10 carbon atoms, and the alkyl moiety may contain an oxygen atom(s), and wherein each R2 independently represents a hydrogen atom or a linear or branched alkyl group having 1 to 18 carbon atoms, and n represents an integer of 0 to 4.

  本发明提供了一种新型化妆品复配剂，该复配剂能够赋予用于头发和皮肤的化妆品以优异的性能，例如保水保湿性能；一种使用该化妆品复配剂的化妆品；以及一种生产该化妆品的方法。本发明的化妆品复配剂含有一种有机铵盐，其阳离子和/或阴离子中具有氢键官能团。在一个较好的实施方案中，阳离子是由下式（I）代表的铵阳离子： N+[R1]n[R2]4-n (I) 其中每个 R1 独立地代表例如羟基烷基，其中至少有一个羟基，烷基是具有 1 至 10 个碳原子的直链或支链基团，烷基可含有一个或多个氧原子，以及 其中每个 R2 独立地代表氢原子或具有 1 至 18 个碳原子的直链或支链烷基，n 代表 0 至 4 的整数。
• COMPOSITION CONTAINING ORGANIC AMMONIUM SALT
  申请人：Miyoshi Oil & Fat Co., Ltd.

  公开号：EP3925672A1

  公开（公告）日：2021-12-22

  Provided is a novel composition with excellent stability which contains an organic ammonium salt. The composition containing an organic ammonium salt of the present invention contains an organic ammonium salt having a hydrogen-bonding functional group(s) in a cation and/or an anion, and a surfactant.

  本发明提供了一种稳定性极佳的新型组合物，其中含有一种有机铵盐。 本发明中含有有机铵盐的组合物包含一种在阳离子和/或阴离子中具有氢键官能团的有机铵盐和一种表面活性剂。
• Biocompatible and conductive hydrogels with tunable physical and electrical properties
  申请人：Northeastern University

  公开号：US11028211B2

  公开（公告）日：2021-06-08

  A biodegradable and biocompatible hydrogel of tunable conductivity is provided. The hydrogel includes a polymer conjugated to a bio-ionic liquid. The mechanical and electrical properties of the hydrogel can be varied by altering the ratio of the polymer to the bio-ionic liquid in the conjugated polymer. These properties can be varied also by changing the percent weight of the conjugated polymer in the hydrogel. A method for preparing the hydrogel is also provided.

  本研究提供了一种具有可调导电性的可生物降解和生物相容性水凝胶。水凝胶包括与生物离子液体共轭的聚合物。通过改变共轭聚合物中聚合物与生物离子液体的比例，可以改变水凝胶的机械和电气性能。这些特性还可以通过改变水凝胶中共轭聚合物的重量百分比来改变。此外，还提供了一种制备水凝胶的方法。
• Switchable ionic liquids for biomass pretreatment and enzymatic hydrolysis
  申请人：National Technology & Engineering Solutions of Sandia, LLC

  公开号：US11118204B2

  公开（公告）日：2021-09-14

  In one aspect, the present invention provides a method for preparing a sugar composition. The method includes: forming a mixture including polysaccharide biomass and an ionic liquid solution, wherein the ionic liquid solution contains water and an ionic liquid, and wherein the ionic liquid contains a dicarboxylic acid anion and a cation. The pH of the mixture is greater than or equal to about 10, and the molar ratio of the dicarboxylic acid anion to the cation is at least about 1:2. The method further includes: maintaining the mixture under conditions sufficient to dissolve at least a portion of the polysaccharide present in the polysaccharide biomass; reducing the pH of the mixture containing the dissolved polysaccharide to at least about 7; adding at least one glycoside hydrolase to the mixture having the reduced pH.

  一方面，本发明提供了一种制备糖组合物的方法。该方法包括：形成包括多糖生物质和离子液体溶液的混合物，其中离子液体溶液包含水和离子液体，离子液体包含二羧酸阴离子和阳离子。混合物的 pH 值大于或等于约 10，二羧酸阴离子与阳离子的摩尔比至少约为 1:2。该方法进一步包括：将混合物保持在足以溶解多糖生物质中存在的至少一部分多糖的条件下；将含有溶解多糖的混合物的pH值降低到至少约7；向pH值降低的混合物中加入至少一种糖苷水解酶。
• Biocompatible oxygen gas generating devices for tissue engineering
  申请人：Rowan University

  公开号：US11389583B2

  公开（公告）日：2022-07-19

  The present invention relates to novel biocompatible oxygen gas generating devices that can be implanted into a living subject. In certain embodiments, the oxygen gas generating devices can be used to deliver oxygen gas to tissue in a subject, thereby stimulating tissue growth and repair. In other embodiments, the devices operate by electrolytically splitting endogenous water in a subject. In yet other embodiments, the device further comprises an implantable supercapacitor capable of supplying energy to the oxygen gas generating device.

  本发明涉及可植入活体的新型生物相容性氧气发生装置。在某些实施例中，氧气发生装置可用于向受试者的组织输送氧气，从而刺激组织生长和修复。在其他实施方案中，这些装置通过电解分离受试者体内的内源性水进行操作。在另一些实施方案中，该装置还包括一个可植入的超级电容器，能够为氧气体发生装置提供能量。