2-(fluorodimethylsilyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | 929887-17-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 溴苄基硼酸频哪醇酯
• 英文名称: 2-(fluorodimethylsilyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
• 英文别名: Fluoro-dimethyl-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane；fluoro-dimethyl-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)silane
• CAS: 929887-17-2
• 化学式: C₈H₁₈BFO₂Si
• 分子量: 204.125
• InChiKey: LGKGAMVGFVCHMG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.33
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  (chlorodimethylsilyl)pinacolborane 、 三氟化锑 以 neat (no solvent) 为溶剂， 以76%的产率得到2-(fluorodimethylsilyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
  参考文献：
  名称：

  Synthesis of Silylboronic Esters Functionalized on Silicon

  摘要：

  New silylpinacolboranes bearing chloro, fluoro, alkoxy, and dialkylamino groups on silicon were synthesized in high yields via derivatization of [(diethylamino)diphenylsilyl]pinacolborane, which was prepared by reaction of [(diethylamino)diphenylsilyl]lithium with (isopropoxy)pinacolborane, and (chlorodimethylsilyl)pinacolborane, prepared by reaction of (dimethylphenylsilyl)pinacolborane with hydrogen chloride in the presence of a catalytic amount of aluminum chloride.

  DOI：

  10.1021/om0609867

文献信息

• Synthesis of Silylboronic Esters Functionalized on Silicon
  作者：Toshimichi Ohmura、Kohei Masuda、Hideki Furukawa、Michinori Suginome

  DOI：10.1021/om0609867

  日期：2007.2.1

  New silylpinacolboranes bearing chloro, fluoro, alkoxy, and dialkylamino groups on silicon were synthesized in high yields via derivatization of [(diethylamino)diphenylsilyl]pinacolborane, which was prepared by reaction of [(diethylamino)diphenylsilyl]lithium with (isopropoxy)pinacolborane, and (chlorodimethylsilyl)pinacolborane, prepared by reaction of (dimethylphenylsilyl)pinacolborane with hydrogen chloride in the presence of a catalytic amount of aluminum chloride.