7,9-Dimethyl-4(oder 1)-aza-indophenazin | 96248-21-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶吡嗪类
• 英文名称: 7,9-Dimethyl-4(oder 1)-aza-indophenazin
• 英文别名: 7,9-dimethyl-10H-pyrido[3',2':5,6]pyrazino[2,3-b]indole；13,15-Dimethyl-2,4,9,17-tetrazatetracyclo[8.7.0.03,8.011,16]heptadeca-1,3(8),4,6,9,11,13,15-octaene；13,15-dimethyl-2,4,9,17-tetrazatetracyclo[8.7.0.03,8.011,16]heptadeca-1,3(8),4,6,9,11,13,15-octaene
• CAS: 96248-21-4
• 化学式: C₁₅H₁₂N₄
• 分子量: 248.287
• InChiKey: RPKXCCPOOGMJKU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  19
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  54.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2,3-二氨基吡啶 、 5,7-二甲基靛红 以 乙二醇 为溶剂， 反应 0.23h， 以90%的产率得到7,9-Dimethyl-4(oder 1)-aza-indophenazin
  参考文献：
  名称：

  Cu doped CdS nanoparticles: A versatile and recoverable catalyst for chemoselective synthesis of indolo[2,3- b ]quinoxaline derivatives under microwave irradiation

  摘要：

  CdS and Cu doped CdS NPs has been obtained successfully using safe agents through a simple aqueous chemical method and characterized by XRD, TEM, SEM, EDAX, UV/VIS and ICP-AES. These investigations revealed that the particle size of the synthesized materials were uniformly distributed in the range of 2-4 nm and confirm the Cu doping in the lattice of CdS NPs. These nanoparticles were exploited to study their catalytic activities toward the chemoselective synthesis of indolo[2,3-blquinoxalines by the reaction of isatins with 1,2-diamines in ethylene glycol under microwave irradiation. The method showed remarkable selectivity for indolo[2,3-b]quinoxalines over 3-imino-isatin, spirobenzimidazole, and ring-opened quinoxalinone derivatives. The catalytic activity of Cu doped CdS NPs was found to be about 18-fold higher under microwave irradiation (MW) as compared to the conventional method. Nanocatalyst plays a dual role of catalyst as well as susceptor, and enhances the overall capacity to absorb MW in the reaction mixture. Doping of Cu promotes the activity and selectivity of CdS nanoparticles indicated by high TOF value with good chemoselectivity. The surface acidity of NPs was measured by FTIR spectra of chemisorbed pyridine. Simple workup, mild reaction conditions, low cost, easy separation, and reusability of the catalyst are some advantages of this method. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molcata.2014.07.022

文献信息

• Cu doped CdS nanoparticles: A versatile and recoverable catalyst for chemoselective synthesis of indolo[2,3- b ]quinoxaline derivatives under microwave irradiation
  作者：Anshu Dandia、Vijay Parewa、Shuchi Maheshwari、Kuldeep S. Rathore

  DOI：10.1016/j.molcata.2014.07.022

  日期：2014.11

  CdS and Cu doped CdS NPs has been obtained successfully using safe agents through a simple aqueous chemical method and characterized by XRD, TEM, SEM, EDAX, UV/VIS and ICP-AES. These investigations revealed that the particle size of the synthesized materials were uniformly distributed in the range of 2-4 nm and confirm the Cu doping in the lattice of CdS NPs. These nanoparticles were exploited to study their catalytic activities toward the chemoselective synthesis of indolo[2,3-blquinoxalines by the reaction of isatins with 1,2-diamines in ethylene glycol under microwave irradiation. The method showed remarkable selectivity for indolo[2,3-b]quinoxalines over 3-imino-isatin, spirobenzimidazole, and ring-opened quinoxalinone derivatives. The catalytic activity of Cu doped CdS NPs was found to be about 18-fold higher under microwave irradiation (MW) as compared to the conventional method. Nanocatalyst plays a dual role of catalyst as well as susceptor, and enhances the overall capacity to absorb MW in the reaction mixture. Doping of Cu promotes the activity and selectivity of CdS nanoparticles indicated by high TOF value with good chemoselectivity. The surface acidity of NPs was measured by FTIR spectra of chemisorbed pyridine. Simple workup, mild reaction conditions, low cost, easy separation, and reusability of the catalyst are some advantages of this method. (C) 2014 Elsevier B.V. All rights reserved.