diethyl(2-oxooxazolidin-3-yl)phosphonate | 26965-07-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: diethyl(2-oxooxazolidin-3-yl)phosphonate
• 英文别名: (2-oxo-oxazolidin-3-yl)-phosphonic acid diethyl ester；3-(Diethoxyphosphinyl)-2oxo-1,3-oxazolidin；3-Diethylphosphon-2-oxo-1,3-oxazolidin；3-Diethoxyphosphoryl-1,3-oxazolidin-2-one
• CAS: 26965-07-1
• 化学式: C₇H₁₄NO₅P
• 分子量: 223.166
• InChiKey: FSICXZIOBGUAQU-UHFFFAOYSA-N

物化性质

• 沸点：
  117-119 °C(Press: 0.03 Torr)
• 密度：
  1.2690 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  65.1
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  methyl N-(2-chloroethyl)-N-diethoxyphosphorylcarbamate 以60%的产率得到
  参考文献：
  名称：

  GUBNITSKAYA E. S.; SEMASHKO Z. T.; GORBATENKO V. I., ZH. ORG. XIMII, 1978, 14, HO 11, 2268-2272

  摘要：

  DOI：

文献信息

• N-Phosphoryl oxazolidinones as effective phosphorylating agents
  作者：Simon Jones、Chaiwat Smanmoo

  DOI：10.1016/j.tetlet.2004.01.003

  日期：2004.2

  A number of N-phosphoryl oxazolidinones have been prepared and evaluated, the best being 5,5-diphenyl oxazolidinones, the utility of which was demonstrated in the phosphorylation of a number of representative primary, secondary, tertiary, and phenolic alcohols. (C) 2004 Elsevier Ltd. All rights reserved.
• Copper-Catalyzed Oxidative Cross-Coupling of <i>H</i>-Phosphonates and Amides to <i>N</i>-Acylphosphoramidates
  作者：Xiongjie Jin、Kazuya Yamaguchi、Noritaka Mizuno

  DOI：10.1021/ol303420g

  日期：2013.1.18

  A simple combination of copper(II) acetate (Cu(OAc)(2)) and an appropriate base could promote oxidative cross-coupling of H-phosphonates and amides using air as a terminal oxidant. The substrate scope was broad with respect to both dialkyl H-phosphonates and nitrogen nucleophiles (including oxazolidinone, lactam, pyrrolidinone, urea, indole, and sulfonamide derivatives), giving the corresponding P-N coupling products in moderate to high yields.
• GUBNITSKAYA E. S.; SEMASHKO Z. T.; GORBATENKO V. I., ZH. ORG. XIMII, 1978, 14, HO 11, 2268-2272
  作者：GUBNITSKAYA E. S.、 SEMASHKO Z. T.、 GORBATENKO V. I.

  DOI：——

  日期：——