Methyl 2-(3-fluorophenyl)sulfanyl-3-oxobutanoate | 265983-05-9

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: Methyl 2-(3-fluorophenyl)sulfanyl-3-oxobutanoate
• 英文别名: methyl 2-(3-fluorophenyl)sulfanyl-3-oxobutanoate
• CAS: 265983-05-9
• 化学式: C₁₁H₁₁FO₃S
• 分子量: 242.271
• InChiKey: UEEJDFNINWDVMY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  68.7
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2-氯乙酰乙酸甲酯 、 3-氟苯硫酚 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 Methyl 2-(3-fluorophenyl)sulfanyl-3-oxobutanoate
  参考文献：
  名称：

  7-HYDROXY-PYRAZOLO[1,5-A] PYRIMIDINE COMPOUNDS AND THEIR USE AS CCR2 RECEPTOR ANTAGONISTS

  摘要：

  式(I)的化合物是CCR2受体的拮抗剂，其中R1-7和A如权利要求中所定义。

  公开号：

  US20130252951A1

文献信息

• [EN] 7-HYDROXY-PYRAZOLO[1,5-A] PYRIMIDINE COMPOUNDS AND THEIR USE AS CCR2 RECEPTOR ANTAGONISTS<br/>[FR] COMPOSÉS 7-HYDROXY-PYRAZOLO-[1,5-A] PYRIMIDINE ET LEUR UTILISATION COMME ANTAGONISTES DU RÉCEPTEUR CCR2
  申请人：PROXIMAGEN LTD

  公开号：WO2012041817A1

  公开（公告）日：2012-04-05

  The compounds of formula (I) are antagonists of the CCR2 receptor Wherein R1-7 and A are as defined in the claims.

  式(I)的化合物是CCR2受体的拮抗剂，其中R1-7和A如权利要求中所定义。
• [EN] 2,3-DIHYDRO-4-OXO-4H-1,3-OXAZINE AND 2-OXO-1,2,5,6-TETRAHYDROPYRIDINE DERIVATIVES AND THEIR USE AS HERBICIDES<br/>[FR] DERIVES DE 2,3-DIHYDRO-4-OXO-4H-1,3-OXAZINE ET DE 2-OXO-1,2,5,6-TETRAHYDROPYRIDINE ET LEUR UTILISATION COMME HERBICIDES
  申请人：AVENTIS CROPSCIENCE SA

  公开号：WO2000024722A1

  公开（公告）日：2000-05-04

  The invention relates to compounds of formula (I), wherein X represents -S(O)v-, an oxygen atom or -NR12; Y represents -O- or -CH2-; R1 represents phenyl, benzyl or thienyl optionally substituted by one to five groups which may be the same or different selected from halogen, hydroxy, alkyl, haloalkyl, alkoxy, haloalkoxy, -S(O)¿n?R?6, -CO¿2R?6, -COR6¿, cyano, nitro, -O(CH¿2?)q-CO2R?6¿ and phenoxy; or alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl or cycloalkyl; R2 represents hydrogen, alkyl, haloalkyl, alkoxyalkyl, haloalkoxyalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, alkoxyalkenyl, -CHO, -COR6, -CO2R6, -CH2NO2, cyano, -CO2H, -COSR?6, -CONR7R8¿, -CH=NOH, -CH=NOR6, -CH=NOCOR6, -CH=NNR?7R8, -CH¿2CN, -CH2NO2 or oxiranyl; or alkyl which is substituted by a group selected from -S(O)nR6, OH, -OCOR?6, -NR7R8¿ and azido; R3 represents CONHR?9, COR10; CO¿2R11; or phenyl optionally substituted by one to five groups which may be the same or different selected from halogen, hydroxy, alkyl, haloalkyl, alkoxy, haloalkoxy, -S(O)¿n?R?6, -CO¿2R?6, -COR6¿, cyano, nitro, -O(CH¿2?)q-CO2R?6¿ and phenoxy; R?4 and R5¿ independently represent alkyl; and to their use as herbicides.
• 7-HYDROXY-PYRAZOLO[1,5-A] PYRIMIDINE COMPOUNDS AND THEIR USE AS CCR2 RECEPTOR ANTAGONISTS
  申请人：Boyd Joe William

  公开号：US20130252951A1

  公开（公告）日：2013-09-26

  The compounds of formula (I) are antagonists of the CCR2 receptor Wherein R 1-7 and A are as defined in the claims.

  式(I)的化合物是CCR2受体的拮抗剂，其中R1-7和A如权利要求中所定义。