ergosta-4,7,22-trien-3-ol | 97583-19-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: ergosta-4,7,22-trien-3-ol
• 英文别名: 24β_F-methyl-cholestatrien-(4.7.22t)-ol-(3β)；3β-Hydroxy-10.13-dimethyl-17β-((1R:4R)-1.4.5-trimethyl-hexen-(2t)-yl)-gonadien-(4.7)；(10R)-3c-Hydroxy-10r.13c-dimethyl-17c-((1R:4R)-1.4.5-trimethyl-hexen-(2t)-yl)-(9tH.14tH)-Δ^4.7-dodecahydro-1H-cyclopenta[a]phenanthren；(24R)-24-Methyl-cholestatrien-(4.7.22t)-ol-(3β)；ergosta-4,7,22E-trien-3beta-ol；(3S,9S,10R,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,3,6,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
• CAS: 97583-19-2
• 化学式: C₂₈H₄₄O
• 分子量: 396.657
• InChiKey: ZAILCZQBNDZEPC-APGDWVJJSA-N

物化性质

• 沸点：
  502.6±49.0 °C(Predicted)
• 密度：
  1.00±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.2
• 重原子数：
  29
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.79
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  ergosta-4,7,22-trien-3-ol 生成 3.5-dinitro-benzoic acid-(ergostatrien-(4.7.22t)-yl-(3β)-ester)
  参考文献：
  名称：

  Windaus; Buchholz, Chemische Berichte, 1939, vol. 72, p. 597,599

  摘要：

  DOI：
• 作为产物：
  描述：

  (22E,24R)-ergosta-4,7,22-triene-3-one 在 aluminum isopropoxide 、 异丙醇 作用下， 生成 ergosta-4,7,22-trien-3-ol
  参考文献：
  名称：

  Windaus; Buchholz, Chemische Berichte, 1939, vol. 72, p. 597,599

  摘要：

  DOI：

文献信息

• Sterols. XIX. epi-Ergosterol and epi-α-Ergostenol
  作者：Russell E. Marker、Oliver Kamm、Joseph F. Laucius、Thomas S. Oakwood

  DOI：10.1021/ja01289a017

  日期：1937.10
• Heilbron et al., Journal of the Chemical Society, 1938, p. 869,874
  作者：Heilbron et al.

  DOI：——

  日期：——
• Climate Change and Trend Detection in Selected Rivers within the Asia-Pacific Region
  作者：Daniel Cluis、Claude Laberge

  DOI：10.1080/02508060108686933

  日期：2001.9

  Global climate change is currently an issue of great concern. This phenomenon was studied using the runoff of large rivers, which can be considered a regional integrator of the local precipitation occurring in their basins. The long-term stationarity and the possibility of trends in streamflow records stored in the databank of the Global Runoff Data Center (GRDC) at the Federal Institute of Hydrology in Koblenz (Germany) were studied. Runoff records originating from. 78 rivers with long monthly runoff series that are geographically distributed throughout the whole Asia-Pacific region were selected for study. For each of the selected rivers, three time series were constructed and analyzed: the mean yearly, and the maximum and minimum monthly discharges. These series were submitted to a two-tier analysis. First, a segmentation procedure developed by Hubert was applied to assess their stationarity. Then the segmented series were submitted to a specialized trend detection software. The results show that about two-thirds of the series have remained stationary and that the monthly minimum runoff exhibited more changing levels (37/78) than the mean (26/78) and maximum (18/78) runoff. Most of the detected changes occurred during the 1960s and 1970s, a period of rapid demographic expansion and urbanization in Asia, when irrigation and other water uses were developed, especially in tropical areas. During the same period and within the area studied, a number of large dams and reservoirs were completed. Since these anthropic interventions could be at the origin of the changes in runoff, there is no regionally consistent evidence supporting global climate change.
• Windaus; Buchholz, Chemische Berichte, 1939, vol. 72, p. 597,599
  作者：Windaus、Buchholz

  DOI：——

  日期：——