campestanyl acetate | 4356-09-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: campestanyl acetate
• 英文别名: 5α-ergostan-3β-yl acetate；(24S)-24-methyl-5α-cholestan-3β-yl acetate；ergostanyl acetate；acetic acid-(5α-ergostan-3β-yl ester)；Essigsaeure-(5α-ergostan-3β-ylester)；(10S)-3c-Acetoxy-10r.13c-dimethyl-17c-((1R:4S)-1.4.5-trimethyl-hexyl)-(5tH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthren；3β-Acetoxy-24β_F-methyl-5α-cholestan；5α-Ergostanyl-(3β)-acetat；3β-Acetoxy-5α-ergostan；Ergostanol acetate；[(3S,5S,8R,9S,10S,13R,14S,17R)-17-[(2R,5S)-5,6-dimethylheptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] acetate
• CAS: 4356-09-6
• 化学式: C₃₀H₅₂O₂
• 分子量: 444.742
• InChiKey: CVXQLNHSKSSFSQ-SHXFDWHISA-N

物化性质

• 熔点：
  144-145 °C
• 沸点：
  451.3±13.0 °C(Predicted)
• 密度：
  0.98±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  10.2
• 重原子数：
  32
• 可旋转键数：
  7
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.97
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  campestanyl acetate 生成 表雄酮
  参考文献：
  名称：

  Fernholz; Chakravorty, Chemische Berichte, 1935, vol. 68, p. 353

  摘要：

  DOI：
• 作为产物：
  描述：

  5α-ergostatrien-(8.14.22t)-one-(3) 在 盐酸 、 乙醇 、 sodium 、 溶剂黄146 、 铂 作用下， 生成 campestanyl acetate
  参考文献：
  名称：

  预测每日最高臭氧水平-I. 具有时间序列误差的回归模型具有一个主要成分触发来适合1991年的臭氧水平。

  摘要：

  这项研究的动机是需要在高臭氧日警告威斯康星州密尔沃基的人口。提出了每天1小时臭氧峰值水平的统计模型。具有时间序列误差的回归（RTSE）模型（包括一个主要成分（PC）触发器）是预测每天1小时峰值臭氧水平的基础。带有PC触发器的RTSE模型首先用于估算1991年臭氧季节在密尔沃基北部的威斯康星大学（UWM-N）测得的每日峰值臭氧。RTSE模型使用每日峰值温度，早晨矢量平均风向和PC触发作为预测变量。PC触发器旨在总结臭氧峰值大于十亿分之100（ppb）时的大气情况。经验证，带有PC触发器的RTSE模型，大大改善了每日峰值臭氧的预测，特别是峰值臭氧大于100 ppb的预测。与没有PC触发的RTSE模型相比，带有PC触发的RTSE模型将R2从0.680提升到0.809。建议使用PC触发的RTSE模型是适当的统计模型，具有实时臭氧预报的潜力。

  DOI：

  10.1080/10473289.2002.10470841

文献信息

• A highly efficient, stereoselective oxyfunctionalization of unactivated carbons in steroids with dimethyldioxirane†
  作者：Takashi Iida、Takeru Yamaguchi、Ryusei Nakamori、Masahiro Hikosaka、Nariyasu Mano、Junichi Goto、Toshio Nambara

  DOI：10.1039/b104938k

  日期：——

  Oxyfunctionalization of unactivated methine carbon atoms with dimethyldioxirane (DMDO) is studied for various substituted steroids related to the 5β-cholane and 5α-cholestane series. A highly efficient, stereoselective, one-step remote oxidation of specific methine carbons is attained by DMDO oxidation under mild conditions to give a variety of novel mono- and dihydroxylated steroids. The reactivity and site selectivity

  研究了二甲基二环氧乙烷（DMDO）对未活化次甲基碳原子的氧官能化作用 类固醇 与5β-胆烷有关 5α-胆甾烷系列。高效，立体选择的一步式遥控器氧化作用 DMDO可实现特定的次甲基碳 氧化作用 在温和的条件下产生各种新颖的单羟基和二羟基 类固醇。远程氧官能化的反应性和位点选择性受结构和空间环境以及分子中目标次甲基碳原子的电子密度程度的影响。非酶促方法可有效地应用于生物活性物质的有效和短步合成类固醇。
• Sterols of the unicellular algae Nematochrysopsis roscoffensis and Chrysotila lamellosa: isolation of (24E)-24-n-propylidenecholesterol and 24-n-propylcholesterol
  作者：Daniel Raederstorff、Michel Rohmer

  DOI：10.1016/0031-9422(84)83024-1

  日期：1984.1

  -propylidenecholest-5-en-3β-ol and 24- n -propylcholest-5-en-3β-ol, and (24 S )-24-ethylcholesta-5,22-dien- 3β-ol (stigmasterol) are the major sterols of Nematochrysopsis roscoffensis , a Chrysophyte of the Sarcinochrysidales order. This unique sterol composition is different from the sterol contents of other Chrysophytes and justifies the peculiar position of the Sarcinochrysidales, which are by some characteristics

  摘要 两种稀有的 C 30 -甾醇，(24 E )-24-n-丙叉胆甾醇-5-en-3β-ol 和 24-n-丙基胆甾醇-5-en-3β-ol，和 (24 S )-24-乙基胆甾醇-5,22-dien-3β-ol（豆甾醇）是 Nematochrysopsis roscoffensis 的主要甾醇，它是结节藻目的金藻。这种独特的甾醇成分不同于其他金藻属的甾醇含量，并且证明了结节藻目的特殊位置是合理的，它们在形态学和生物学上与褐藻纲有关。(24 S )-24-methylcholesta-5,22-dien-3β-ol (24-epibrassicasterol) 作为 Chrysotila lamellosa 中的主要甾醇的存在与从其他 Prymnesiophyceae 获得的少数先前结果一致，尽管存在另一种主要甾醇，(24 R )-24-乙基胆甾醇-5，
• Stereoselective Synthesis and NMR Characterization of C-24 Epimeric Pairs of 24-Alkyl Oxysterols
  作者：Shoujiro Ogawa、Hiroaki Kawamoto、Takashi Mitsuma、Hiroki Fujimori、Tatsuya Higashi、Takashi Iida

  DOI：10.1007/s11745-012-3739-1

  日期：2013.2

  be effectively characterized by the aromatic solvent‐induced shift (ASIS) by C5D5N, particularly for the difference in the 13C resonances in the substituted cholestane side chain. A method for differentiating the 1H and 13C signal assignment of the terminal 26‐/27‐CH3 in the iso‐octane side chain was also discussed on the basis of a combined use of the preferred conformational analysis and HMQC and

  两对C-24差向异构体（24 - [R ）- /（24小号）-24羟基-24-甲基-5- α -胆甾3 β基乙酸酯和（24 - [R ） - /（24小号）-25-羟基-24-甲基-5- α -胆甾3 β基乙酸酯以及一些相关的24乙基氧固醇类似物立体选择性地直接从各自的父由远程合成24烷基固醇ö -insertion与2,6-反应催化量的（5,10,15,20-四甲叉基卟啉）钌（II）羰基络合物[Ru（TMP）CO]和HBr存在下的二氯吡啶N-氧化物（DCP）。1 H‐和13解释了用来区分两个差向异构对的C-NMR信号。发现C-24上的C-24烷基氧固醇是由C 5 D 5 N引起的芳族溶剂诱导的位移（ASIS）有效表征的，特别是对于取代的胆甾烷侧链中13 C共振的差异。在iso中区分端子26- / 27-CH 3的1 H和13 C信号分配的方法还结合了首选的构象分析和HMQC和HMBC技术
• Effects of Engine Speed and Accessory Load on Idling Emissions from Heavy-Duty Diesel Truck Engines
  作者：Christie-Joy Brodrick、Harry A. Dwyer、Mohammad Farshchi、D. Bruce Harris、Foy G. King

  DOI：10.1080/10473289.2002.10470838

  日期：2002.9

  A nontrivial portion of. heavy-duty vehicle emissions of NOx and particulate matter (PM) occurs during idling. Regulators and the environmental community are interested in curtailing truck idling emissions, but current emissions models do not characterize them accurately, and little quantitative data exist to evaluate the relative effectiveness of various policies. The objectives of this study were to quantify the effect of accessory loading and engine speed on idling emissions from a properly functioning, modern, heavy-duty diesel truck and to compare these results with data from earlier model year vehicles. It was found that emissions during idling varied greatly as. a function of engine model year, engine speed,and accessory load conditions. For the 1999 model year Class 8 truck tested, raising the engine speed from 600 to 1050 rpm and turning on the air conditioning resulted in a 2.5-fold increase in NOx emissions in grams per hour, a 2-fold increase in CO2 emissions, and a 5-fold increase in CO emissions while idling. On a grams per gallon fuel basis, NOx emissions while idling were approximately twice as high as those at 55 mph. The CO2 emissions at the two conditions were closer. The NOx emissions from the 1999 truck while idling with air conditioning running were slightly more than those of two 1990 model year trucks under equivalent conditions, and the hydrocarbon (HC) and CO emissions were significantly lower. It was found that the NOx emissions used in the California Air Resources Board's (CARB) EMFAC2000 and the U.S. Environmental Protection Agency's (EPA) MOBILE5b emissions inventory models were lower than those measured in all of the idling conditions tested on the 1999 truck.
• DE736845
  申请人：——

  公开号：——

  公开（公告）日：——