Diethyl-penta-1,3-diynyl-amine | 134516-62-4

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Diethyl-penta-1,3-diynyl-amine
• 英文别名: N,N-diethylpenta-1,3-diyn-1-amine
• CAS: 134516-62-4
• 化学式: C₉H₁₃N
• 分子量: 135.209
• InChiKey: RNYQWCALNNTTAV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  10
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  二硫化碳 、 Diethyl-penta-1,3-diynyl-amine 生成 2-N,N-diethylaminothieno<2,3-b>thiophene
  参考文献：
  名称：

  A One-Pot Procedure for Thieno[2,3-b]thiophene and Some of its Derivatives Using Derivatives of 1,3-Pentadiyne and Carbon Disulfide as Building Units

  摘要：

  Thieno[2,3-b]thiophene and its 2-methyl- and 2-N,N-dialkylamino derivatives have been obtained in fair yields in a one-pot procedure using the diynes CH3C = CC = CR (R = Me3Si, CH3, NMe2, NEt2) and carbon disulfide as building blocks and n-butyllithium, potassium tert-butoxide and t-butylalcohol as reagents.

  DOI：

  10.1080/00397919108020803
• 作为产物：
  描述：

  (二乙基氨基)甲醇 在 六甲基磷酰三胺 、 potassium tert-butylate 、 氨 、 copper diacetate 、 sodium amide 作用下， 以 1,4-二氧六环 、 乙醚 、 叔丁醇 为溶剂， 反应 2.0h， 生成 Diethyl-penta-1,3-diynyl-amine
  参考文献：
  名称：

  An Efficient Synthetic Method for 1-N,N-Dialkylamino-1,3-Pentadiynes

  摘要：

  The diyne amines CH3C = CC = CNR2 (R = CH3 or C2H5) have been synthesized with greater than 50% overall yields starting from 1,4-dichloro-2-butyne, the last step being a base-catalyzed isomerization of HC = CC = CCH2NR2.

  DOI：

  10.1080/00397919108020792

文献信息

• BRANDSMA, L.;WALDA, B.;OOSTERVELD, I., SYNTH. COMMUN., 21,(1991) N, C. 73-77
  作者：BRANDSMA, L.、WALDA, B.、OOSTERVELD, I.

  DOI：——

  日期：——
• JONG, R. L. P. DE;BRANDSMA, L., SYNTH. COMMUN., 21,(1991) N, C. 145-149
  作者：JONG, R. L. P. DE、BRANDSMA, L.

  DOI：——

  日期：——
• An Efficient Synthetic Method for 1-N,N-Dialkylamino-1,3-Pentadiynes
  作者：L. Brandsma、B. Walda、I. Oosterveld

  DOI：10.1080/00397919108020792

  日期：1991.1

  The diyne amines CH3C = CC = CNR2 (R = CH3 or C2H5) have been synthesized with greater than 50% overall yields starting from 1,4-dichloro-2-butyne, the last step being a base-catalyzed isomerization of HC = CC = CCH2NR2.
• A One-Pot Procedure for Thieno[2,3-b]thiophene and Some of its Derivatives Using Derivatives of 1,3-Pentadiyne and Carbon Disulfide as Building Units
  作者：R. L. P. de Jong、L. Brandsma

  DOI：10.1080/00397919108020803

  日期：1991.1

  Thieno[2,3-b]thiophene and its 2-methyl- and 2-N,N-dialkylamino derivatives have been obtained in fair yields in a one-pot procedure using the diynes CH3C = CC = CR (R = Me3Si, CH3, NMe2, NEt2) and carbon disulfide as building blocks and n-butyllithium, potassium tert-butoxide and t-butylalcohol as reagents.