2,7-di-tert-butyl-9,9-dimethyl-4,5-bis(diphenylarsino)xanthene | 265667-32-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: 2,7-di-tert-butyl-9,9-dimethyl-4,5-bis(diphenylarsino)xanthene
• 英文别名: (2,7-Ditert-butyl-5-diphenylarsanyl-9,9-dimethylxanthen-4-yl)-diphenylarsane
• CAS: 265667-32-1
• 化学式: C₄₇H₄₈As₂O
• 分子量: 778.741
• InChiKey: YJXMOUBCGUMLRS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.75
• 重原子数：
  50
• 可旋转键数：
  8
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  [Pd(η3-1,1-Me2allyl)(μ-Cl)]2 、 silver trifluoromethanesulfonate 、 2,7-di-tert-butyl-9,9-dimethyl-4,5-bis(diphenylarsino)xanthene 以 二氯甲烷 为溶剂， 生成 [(C13H4O(C(CH3)3)(CH3)2(As(C6H5)2)2)Pd(η(3)-3-methyl-butenyl)][SO3CF3]
  参考文献：
  名称：

  The effect of ligand donor atoms on the regioselectivity in the palladium catalyzed allylic alkylation

  摘要：

  The regioselectivity of the palladium catalyzed allylic alkylation was studied systematically using bidentate ligands based on a xanthene backbone, bearing different donor atoms. The nature of the ligand donor atoms has a pronounced influence on the regioselectivity of the reaction. The results can be explained by a mechanism that distinguishes two 'stages' in the alkylation reaction. Ligands bearing strong pi-acceptor donor atoms induce the formation of branched products (60% for the P-P derivative), whereas the use of ligands with weak pi-acceptor donor atoms mainly yields linear products ( > 99% for the N-N derivative). (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0020-1693(01)00694-6
• 作为产物：
  描述：

  二苯胂化氯 、 4,5-二溴-2,7-二叔丁基-9,9-二甲基呫吨 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 1.0h， 以83%的产率得到2,7-di-tert-butyl-9,9-dimethyl-4,5-bis(diphenylarsino)xanthene
  参考文献：
  名称：

  使用铂/锡催化剂选择性加氢甲酰化烯烃的新型胂配体

  摘要：

  报道了新型广角胂基配体的合成及其在铂/锡催化的辛-1-烯羰基化反应中的应用；使用混合的膦/胂配体获得了前所未有的高活性和选择性。

  DOI：

  10.1039/a906903h

文献信息

• Wide bite angle amine, arsine and phosphine ligands in rhodium- and platinum/tin-catalysed hydroformylation †
  作者：Lars A. van der Veen、Peter K. Keeven、Paul C. J. Kamer、Piet W. N. M. van Leeuwen

  DOI：10.1039/b002126l

  日期：——

  and [(ligand)Rh(CO)2]2 complexes. In the platinum/tin-catalysed hydroformylation the xantarsine and the mixed xantphosarsine ligands proved to be superior to the xantphos ligands. The remarkably high selectivity and activity that is displayed by the mixed xantphosarsine ligand is explained by its wide natural bite angle and the formation of cis co-ordinated platinum complexes.

  新的宽咬角 胺，a和混合的膦胺和次膦酸酯 配体基于x吨骨架合成。这些的配位化学和催化性能配体 与父母的相比 膦 配体。这胺 基于 an吨 配体 不会形成铑氢化物配合物，因此铑加氢甲酰化效果很差 催化剂。金刚烷胺和混合的黄磷肌氨酸的催化性能配体 与 黄药 配体它们形成相似的（配体）Rh（CO）2 H和[（配体）Rh（CO）2 ] 2配合物。在铂/锡催化的加氢甲酰化反应中，金刚烷胺和混合的黄磷肌氨酸配体 被证明优于 黄药 配体。混合的黄磷肌氨酸盐显示出极高的选择性和活性配体其宽的自然咬合角和顺式配位的铂络合物的形成解释了这一点。
• The effect of ligand donor atoms on the regioselectivity in the palladium catalyzed allylic alkylation
  作者：Richard J van Haaren、Peter H Keeven、Lars A van der Veen、Kees Goubitz、Gino P.F van Strijdonck、Henk Oevering、Joost N.H Reek、Paul C.J Kamer、Piet W.N.M van Leeuwen

  DOI：10.1016/s0020-1693(01)00694-6

  日期：2002.1

  The regioselectivity of the palladium catalyzed allylic alkylation was studied systematically using bidentate ligands based on a xanthene backbone, bearing different donor atoms. The nature of the ligand donor atoms has a pronounced influence on the regioselectivity of the reaction. The results can be explained by a mechanism that distinguishes two 'stages' in the alkylation reaction. Ligands bearing strong pi-acceptor donor atoms induce the formation of branched products (60% for the P-P derivative), whereas the use of ligands with weak pi-acceptor donor atoms mainly yields linear products ( > 99% for the N-N derivative). (C) 2002 Elsevier Science B.V. All rights reserved.
• Novel arsine ligands for selective hydroformylation of alk-1-enes employing platinum/tin catalysts
  作者：Lars A. van der Veen、Peter K. Keeven、Paul C. J. Kamer、Piet W. N. M. van Leeuwen

  DOI：10.1039/a906903h

  日期：——

  The synthesis and application of new wide bite angle arsine based ligands in the platinum/tin-catalysed hydroformylation of oct-1-ene is reported; an unprecedented high activity and selectivity is obtained employing a mixed phosphine/arsine ligand.

  报道了新型广角胂基配体的合成及其在铂/锡催化的辛-1-烯羰基化反应中的应用；使用混合的膦/胂配体获得了前所未有的高活性和选择性。