2-methyl-6-phenylimidazo<1,2-a>pyrazin-3(7H)-one hydrochloride | 56888-73-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 咪唑并吡嗪类
• 英文名称: 2-methyl-6-phenylimidazo<1,2-a>pyrazin-3(7H)-one hydrochloride
• 英文别名: 2-methyl-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one;hydrochloride
• CAS: 56888-73-4
• 化学式: C₁₃H₁₁N₃O*ClH
• 分子量: 261.711
• InChiKey: LFHBEYPSICHHDR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  18.0
• 可旋转键数：
  1.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  50.68
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  2-氨基-5-苯基吡嗪 、 丙酮醛 在 盐酸 作用下， 以 乙醇 为溶剂， 反应 4.0h， 生成 2-methyl-6-phenylimidazo<1,2-a>pyrazin-3(7H)-one hydrochloride
  参考文献：
  名称：

  Imidazolopyrazinones as potential antioxidants

  摘要：

  A series of imidazolopyrazinones 3, substituted at C-2, and C-2/C-6, has been prepared. The compounds behaved as quenchers of superoxide anion. The more active compounds are structurally related to coelenterazine, a natural substrate of marine bioluminescence. Theoretical parameters based on Hartree-Fock instabilities hake been examined. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0960-894x(01)00445-0

文献信息

• Imidazolopyrazinones as potential antioxidants
  作者：Ingrid Devillers、Georges Dive、Catherine De Tollenaere、Bénédicte Falmagne、Bertrand de Wergifosse、Jean-François Rees、Jacqueline Marchand-Brynaert

  DOI：10.1016/s0960-894x(01)00445-0

  日期：2001.9

  A series of imidazolopyrazinones 3, substituted at C-2, and C-2/C-6, has been prepared. The compounds behaved as quenchers of superoxide anion. The more active compounds are structurally related to coelenterazine, a natural substrate of marine bioluminescence. Theoretical parameters based on Hartree-Fock instabilities hake been examined. (C) 2001 Elsevier Science Ltd. All rights reserved.