(2-Chlorophenyl)phosphane | 53772-57-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (2-Chlorophenyl)phosphane
• CAS: 53772-57-9
• 化学式: C₆H₆ClP
• 分子量: 144.54
• InChiKey: KUXIQKVLTGHSAN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

文献信息

• [EN] PROCESS FOR PREPARING ACYLPHOSPHANES AND DERIVATIVES THEREOF<br/>[FR] PROCEDE DE PREPARATION D'ACYLPHOSPHANES ET DE DERIVES D'ACYLPHOSPHANES
  申请人：CIBA SC HOLDING AG

  公开号：WO2005014605A1

  公开（公告）日：2005-02-17

  The present invention relates to a new, selective process for the preparation of mono- and bisacylphosphanes of formula (I) n and m are each independently of the other 1 or 2; R1, if n = 1, is e.g. phenyl R1, if n = 2, is e.g. C1-C18alkylene or phenylene; R2 is e. g. C1-C18alkyl, phenyl or substituted phenyl; R3 is e. g. C1-C18alkyl, by (1) reacting a phosphorous halide of formula Ila or a phosphorous halide oxide of formula (Ilb) or a phosphorous halide sulfide of formula (IIc) with an alkali metal in a solvent in the presence of a proton source; (2) subsequent reaction with m acid halides of formula (III) An oxidation step may follow to obtain mono- and bisacylphosphane oxides or mono-and bisacylphosphane sulfides.

  本发明涉及一种新的选择性制备式(I)的单酰基和双酰基膦化合物的方法，其中n和m分别独立取1或2；R1，如果n=1，则为例如苯基；如果n=2，则为例如C1-C18烷基或苯基；R2为例如C1-C18烷基、苯基或取代苯基；R3为例如C1-C18烷基，通过以下步骤实现：(1)在溶剂中，在质子源的存在下，将式IIa的磷卤化物或式IIb的磷卤化物氧化物或式IIc的磷卤化物硫化物与碱金属反应；(2)随后与m个式(III)的酸卤化物反应。氧化步骤可能随后进行，以获得单酰基和双酰基膦氧化物或单酰基和双酰基膦硫化物。
• PHOSPHINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEROXIDE SCAVENGER USING THE SAME
  申请人：Shioji Kosei

  公开号：US20110015440A1

  公开（公告）日：2011-01-20

  The invention provides a novel peroxide scavenger comprising a phosphine compound represented by general formula [I]: wherein Z 1 and Z 2 each represents a cyclic group; Ar represents an arylene group; R represents an aliphatic hydrocarbon group; Y represents phosphorus (P), nitrogen (N), or bismuth (Bi); and R 1 , R 2 , and R 3 each represents a cyclic group, particularly a peroxide scavenger that can scavenge peroxides such as reactive oxygen species which are generated in mitochondria upon exposure to oxidative stress and localized in mitochondria. The phosphine compound of the invention is oxidized by the peroxides localized in mitochondria to increase the fluorescence intensity, whereby the peroxides can be scavenged.

  该发明提供了一种新型过氧化物清除剂，包括由通式[I]所表示的膦化合物：其中Z1和Z2分别表示环状基团；Ar表示芳基基团；R表示脂肪烃基团；Y表示磷（P）、氮（N）或铋（Bi）；而R1、R2和R3分别表示环状基团，特别是一种过氧化物清除剂，可以清除在暴露于氧化应激时在线粒体中生成并定位在线粒体中的反应性氧化物种，该发明的膦化合物被定位在线粒体中的过氧化物氧化以增加荧光强度，从而可以清除过氧化物。
• LIGAND COMPOUND, CATALYST SYSTEM FOR OLEFIN OLIGOMERIZATION, AND METHOD FOR OLIGOMERIZING OLEFINS USING THE SAME
  申请人：LG CHEM, LTD.

  公开号：US20170260305A1

  公开（公告）日：2017-09-14

  The present invention relates to a compound represented by the chemical formula 1, a catalyst system for olefin oligomerization comprising the same, and a method for oligomerizign olefins using the same, and the catalyst system for olefin oligomerization according to the present invention has excellent catalytic activity as well as high selectivity for 1-hexene or 1-octene, thereby enabling more efficient preparation of alpha-olefins.

  本发明涉及一种化学式1表示的化合物，包括相同的烯烃寡聚催化剂体系，以及使用该体系进行烯烃寡聚的方法。根据本发明的烯烃寡聚催化剂体系具有优异的催化活性，以及对1-己烯或1-辛烯的高选择性，从而实现更高效的α-烯烃制备。
• [EN] BIDENTATE SECONDARY PHOSPHINE OXIDE CHIRAL LIGANDS FOR USE IN ASYMMETRIC ADDITION REACTIONS<br/>[FR] LIGANDS CHIRAUX BIDENTATES LIÉS À UN OXYDE DE PHOSPHINE SECONDAIRE ET LEUR UTILISATION DANS DES RÉACTIONS D'ADDITION ASYMÉTRIQUE
  申请人：SOLVIAS AG

  公开号：WO2009065783A1

  公开（公告）日：2009-05-28

  Compounds of the formula I, in the form of mixtures comprising predominantly one enantiomer or in the form of pure enantiomers, secondary phosphine-Q-P*(=O)HR1 (I) in which secondary phosphine is a C-bonded, secondary phosphine group -P(R) 2; in which R is in each case independently hydrocarbon radicals or heterohydrocarbon radicals; Q is a bivalent, achiral, aromatic base skeleton, a bivalent, achiral ferrocene base skeleton, an optionally substituted bivalent cycloalkane or heterocycloalkane skeleton, or a C 1-C 4-alkylene skeleton, and in which base skeletons a secondary phosphine group is bonded directly to a carbon atom, or, in the case of cyclic base skeletons, directly to a carbon atom or via a C1-C 4-alkylene group, and in which base skeletons a P-chiral group -P*(O)HR1 is bonded to a carbon atom such that the phosphorus atoms are linked via 1 to 7 atoms of a carbon chain optionally interrupted by heteroatoms from the group of O, S, N, Fe or Si; P* is a chiral phosphorus atom; and R1 is a hydrocarbon radical, a C-bonded heterohydrocarbon radical or a ferrocenyl radical, with the proviso that R1 is an achiral ferrocenyl radical when Q is an achiral ferrocenyl base skeleton. Metal complexes of these ligands in a molarratio of ligand to metal of about 1.3:1 to 0.9:1are homogeneous catalysts for asymmetric addition reactions, particularly hydrogenations.

  公式I的化合物以纯对映体形式或以主要含有一种对映体的混合物的形式存在，其中二级膦-Q-P *（= O）HR1（I）中的二级膦是C-键结的二级膦基团-P（R）2;其中R分别是烃基或杂原子烃基；Q是二价的、不手性的、芳香基骨架、二价的、不手性的二茂铁基骨架、可选取代的二价环烷烃或杂环烷烃骨架，或C1-C4-烷基骨架，在这些基骨架中，二级膦基团直接键合到碳原子上，或在环状基骨架的情况下，直接键合到碳原子或通过C1-C4-烷基链键合，其中在这些基骨架中，P-手性基团-P *（O）HR1 键合到碳原子，使得磷原子通过由O、S、N、Fe或Si组成的杂原子随意中断的1到7个碳链原子链接；P *是手性磷原子；R1是烃基、C-键结的杂原子烃基或二茂铁基基团，但当Q是不手性的二茂铁基骨架时，R1是不手性的二茂铁基基团。这些配体的金属配合物在配体与金属的摩尔比约为1.3:1至0.9:1的情况下是对称加成反应的均相催化剂，特别是氢化反应。
• [EN] HIGH TRIPLET ENERGY PHOSPHINE OXIDE COMPOUNDS FOR OLED APPLICATION<br/>[FR] COMPOSÉS D'OXYDE DE PHOSPHINE À ÉNERGIE DE TRIPLET ÉLEVÉE POUR APPLICATION OLED
  申请人：DOW GLOBAL TECHNOLOGIES LLC

  公开号：WO2018125512A1

  公开（公告）日：2018-07-05

  Phosphine oxide compounds which have a high Triplet Energy used in an emission layer of Organic Light Emitting Devices (OLEDs) and OLEDs comprising the compounds are disclosed.

  本发明涉及一种在有机发光器件（OLED）的发射层中使用高三重态能量的膦氧化物化合物，以及包含该化合物的OLED。