2-phenyl-butane-1-thiol | 34335-60-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-phenyl-butane-1-thiol
• 英文别名: 2-Phenyl-butan-1-thiol；2-Phenyl-1-butanethiol；2-Phenylbutane-1-thiol
• CAS: 34335-60-9
• 化学式: C₁₀H₁₄S
• 分子量: 166.287
• InChiKey: WZNVCXKQTAIAIT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  甲基膦酞二氯 、 2-phenyl-butane-1-thiol 在 三乙胺 作用下， 以 氘代氯仿 为溶剂， 反应 0.17h， 生成 1-[Methyl(2-phenylbutylsulfanyl)phosphoryl]sulfanylbutan-2-ylbenzene
  参考文献：
  名称：

  Methylphosphonic dichloride as reagent for the determination of the enantiomeric excess of chiral thiols. scope and limitations

  摘要：

  DOI：

  10.1016/s0040-4020(01)89938-5
• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 potassium hydrosulfide 作用下， 生成 2-phenyl-butane-1-thiol 、 bis-(2-phenyl-butyl)-disulfide
  参考文献：
  名称：

  Levene; Mikeska; Passoth, Journal of Biological Chemistry, 1930, vol. 88, p. 27,57

  摘要：

  DOI：

文献信息

• Method for producing anellated tetrahydro-{1h}-triazoles
  申请人：——

  公开号：US20040097728A1

  公开（公告）日：2004-05-20

  The present invention relates to a process for preparing fused tetrahydro-[ 1 H]-triazoles of the formula I 1 where the variables R a , Z, Z 1 , X, W, n and Q are as defined in claim 1, by cyclization of compounds of the formula II 2 where R is C(X)OR 2 or C(X)SR 2 , where X is oxygen or sulfur, and R 2 is as defined in claim 1, in the presence of a base. The invention also relates to compounds of the formula I where W is sulfur if Z is a methylene group optionally substituted by R a , and furthermore to compounds of the formula I where Q is a benzoxazole or benzothiazole radical, and to the use of these compounds as herbicides.

  本发明涉及一种制备公式I的熔融四氢咪唑的方法，其中变量Ra、Z、Z1、X、W、n和Q如权利要求1中定义，通过在碱存在下，将公式II的化合物环化得到，其中R为C(X)OR2或C(X)SR2，其中X为氧或硫，R2如权利要求1中定义。该发明还涉及公式I的化合物，其中如果Z是可选地由Ra取代的亚甲基基团，则W为硫，此外还涉及公式I的化合物，其中Q为苯并噁唑或苯并噻唑基团，并将这些化合物用作除草剂。
• Alpha-substituted carboxylic acid derivatives
  申请人：SANKYO COMPANY, LIMITED

  公开号：US20030069294A1

  公开（公告）日：2003-04-10

  The &agr;-substituted carboxylic acid derivatives having the formula (I): 1 wherein R 1 is an alkyl group, etc., R 2 is a hydrogen atom, etc., R 3 is a hydrogen atom, etc., A is ═CH-group, etc., B is an oxygen atom, etc., W 1 is a C 1 -C 8 alkylene group, W 2 is a single bond or a C 1 -C 8 alkylene group, X is a hydrogen atom, etc., Y is an oxygen atom, etc., and Z 1 is an alkoxy group, etc., and pharmacologically acceptable salts, esters and amides thereof are useful for treatment and/or prevention of diabetes mellitus, impaired glucose tolerance, gestational diabetes mellitus, or the like. Some of the derivatives of the formula (I) are novel compounds.

  具有如下式(I)的α-取代羧酸衍生物，其中R1是烷基基团，R2是氢原子，R3是氢原子，A是═CH-基团，B是氧原子，W1是C1-C8烷基基团，W2是单键或C1-C8烷基基团，X是氢原子，Y是氧原子，Z1是烷氧基团，其药理学上可接受的盐、酯和酰胺对于治疗和/或预防糖尿病、糖耐量受损、妊娠期糖尿病等疾病是有用的。其中一些具有如上式(I)的衍生物是新化合物。
• Medicinal compositions containing diuretic and insulin resistance-improving agent
  申请人：Takaoka Masaya

  公开号：US20050288339A1

  公开（公告）日：2005-12-29

  The present invention relates to a pharmaceutical composition comprising an insulin sensitizer and a diuretic which can prevent or treat side effects such as edema, cardiac enlargement, body fluid retension or hydrothorax caused by administration of an insulin sensitizer.

  本发明涉及一种药物组合物，包括胰岛素增敏剂和利尿剂，可以预防或治疗由于胰岛素增敏剂的使用引起的水肿、心脏肥大、体液潴留或胸水等副作用。
• ALKYL PHENYL SULFIDE DERIVATIVE AND PEST CONTROL AGENT
  申请人：KUMIAI CHEMICAL INDUSTRY CO., LTD.

  公开号：US20150087833A1

  公开（公告）日：2015-03-26

  An alkyl phenyl sulfide derivative represented by the general formula [I] or an agriculturally acceptable salt thereof, and a pest control agent containing the derivative or the salt as an active ingredient. [in the above formula, R 1 is, for example, a C 1 ˜C 6 alkyl group which is mono- or poly-substituted with halogen atom; R 2 is, for example, a halogen atom or a C 1 ˜C 6 alkyl group; R 3 is, for example, a hydrogen atom or a halogen atom; and R 4 is, for example, a hydrogen atom or a C 1 ˜C 12 alkyl group.] The derivative or the salt has an excellent pest control effect.

  一种由通式[I]表示的烷基苯基硫醚衍生物或其农业上可接受的盐，以及包含该衍生物或盐作为活性成分的农药。[在上述公式中，R1是例如一种C1〜C6烷基，其单个或多个取代为卤素原子; R2是例如卤素原子或C1〜C6烷基; R3是例如氢原子或卤素原子; R4是例如氢原子或C1〜C12烷基。]该衍生物或盐具有出色的杀虫效果。
• Process for purification of 1,2-unsaturated carboxylic acids and/or esters thereof
  申请人：MITSUBISHI PETROCHEMICAL CO., LTD.

  公开号：EP0169254A1

  公开（公告）日：1986-01-29

  A 1,2-unsaturated carboxylic acid or its ester such as acrylic or methacrylic acid or its alkyl ester is purified to remove aldehyde impurities contained therein by treating the acid or its ester with an SH-containing compound in the presence of an acid catalyst.

  1,2-不饱和羧酸或其酯，如丙烯酸或甲基丙烯酸或其烷基酯，在酸催化剂存在下，用含 SH 的化合物处理该酸或其酯，可净化去除其中的醛杂质。