2,2,2,4,4-Pentafluoro-4-methylamino-1,3-dimethyl-1,3,2λ⁵,4λ⁵-diazadiphosphetidine | 77392-89-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2,2,2,4,4-Pentafluoro-4-methylamino-1,3-dimethyl-1,3,2λ⁵,4λ⁵-diazadiphosphetidine
• 英文别名: 2,2,2,4,4-Pentafluoro-1,3-dimethyl-4-methylamino-1,3,2λ⁵,4λ⁵-diazadiphosphetidin；2,2,4,4,4-pentafluoro-N,1,3-trimethyl-1,3,2λ5,4λ5-diazadiphosphetidin-2-amine
• CAS: 77392-89-3
• 化学式: C₃H₁₀F₅N₃P₂
• 分子量: 245.072
• InChiKey: WFEQHLHHUCJFTA-UHFFFAOYSA-N

物化性质

• 沸点：
  32 °C(Press: 0.075 Torr)

计算性质

• 辛醇/水分配系数(LogP)：
  3.19
• 重原子数：
  13.0
• 可旋转键数：
  1.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  18.51
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  2,2,2,4,4-Pentafluoro-4-methylamino-1,3-dimethyl-1,3,2λ⁵,4λ⁵-diazadiphosphetidine 在 18-冠醚-6 potassium fluoride 作用下， 以 乙腈 为溶剂， 反应 6.0h， 以38.9%的产率得到2,2,4,4-Tetrafluoro-2,4-bis(methylamino)-1,3-dimethyl-1,3,2λ⁵,4λ⁵-diazadiphosphetidine
  参考文献：
  名称：

  Fluordiazadiphosphetidine, 24. Mitt.: Reaktion monosubstituierter Fluordiazadiphosphetidine mit Kaliumfluorid/Kronenether

  摘要：

  The reactivity of some monosubstituted fluorodiazadiphosphetidines towards potassium fluoride utilizing 18-crown-6-ether as a phase transfer catalyst has been studied. The following compounds were investigated: 2,2,2,4,4-pentafluoro-4-methoxy-1,3-dimethyl-1,3,2lambda5,4lambda5-diazadiphosphetidine, 2,2,2,4,4-pentafluoro-4-methylamino-1,3-dimethyl-1,3,2lambda5,4lambda5 diazadiphosphetidine, 2,2,2,4,4-pentafluoro-4-methylthio-1,3-dimethyl-1,3,2lambda5,4lambda5-diazadiphosphetidine, and a 1:1 mixture of 2,2,2,4,4-pentafluoro-4-(N2,N2-dimentyl-hydrazino)-1,3-dimethyl-1,3,2lambda5,4lambda5-diazadiphosphetidine and 2,2,2,4,4-pentafluoro-4-methylamino-1,3-dimethyl-1,3,2lambda5,4lambda5-diazadiphosphetidine. All reactions proceeded in a similar way and led to the disubstituted derivates of the starting materials and the potassium salt K2(CH3NPF4)2. In this way 2,2,4,4-tetrafluoro-2-methylamino-4-(N2,N2-dimethyl-hydrazino)-1,3-dimethyl-1,3,2lambda5,4lambda5-diazadiphosphetidine has been synthesized for the first time and a new way has been found for the synthesis of several compounds reported in literature.

  DOI：

  10.1007/bf00819518
• 作为产物：
  描述：

  methyltrimethylsilylamine 、 2,2,2,4,4,4-hexafluoro-1,3-dimethyl-1,3,2λ⁵,4λ⁵-diazadiphosphetidine 以60%的产率得到
  参考文献：
  名称：

  KUBJACEK M.; UTVARY K., MONATSH. CHEM., 1981, 112, NO 3, 305-315

  摘要：

  DOI：
• 作为试剂：
  描述：

  2,2,2,4,4-Pentafluoro-4-(N²,N²-dimethylhydrazino)-1,3-dimethyl-1,3,2λ⁵,4λ⁵-diazadiphosphetidine 在 18-冠醚-6 2,2,2,4,4-Pentafluoro-4-methylamino-1,3-dimethyl-1,3,2λ⁵,4λ⁵-diazadiphosphetidine 作用下， 以 乙腈 为溶剂， 反应 70.0h， 以35.73%的产率得到2,2,4,4-Tetrafluoro-2,4-bis(methylamino)-1,3-dimethyl-1,3,2λ⁵,4λ⁵-diazadiphosphetidine
  参考文献：
  名称：

  Fluordiazadiphosphetidine, 24. Mitt.: Reaktion monosubstituierter Fluordiazadiphosphetidine mit Kaliumfluorid/Kronenether

  摘要：

  The reactivity of some monosubstituted fluorodiazadiphosphetidines towards potassium fluoride utilizing 18-crown-6-ether as a phase transfer catalyst has been studied. The following compounds were investigated: 2,2,2,4,4-pentafluoro-4-methoxy-1,3-dimethyl-1,3,2lambda5,4lambda5-diazadiphosphetidine, 2,2,2,4,4-pentafluoro-4-methylamino-1,3-dimethyl-1,3,2lambda5,4lambda5 diazadiphosphetidine, 2,2,2,4,4-pentafluoro-4-methylthio-1,3-dimethyl-1,3,2lambda5,4lambda5-diazadiphosphetidine, and a 1:1 mixture of 2,2,2,4,4-pentafluoro-4-(N2,N2-dimentyl-hydrazino)-1,3-dimethyl-1,3,2lambda5,4lambda5-diazadiphosphetidine and 2,2,2,4,4-pentafluoro-4-methylamino-1,3-dimethyl-1,3,2lambda5,4lambda5-diazadiphosphetidine. All reactions proceeded in a similar way and led to the disubstituted derivates of the starting materials and the potassium salt K2(CH3NPF4)2. In this way 2,2,4,4-tetrafluoro-2-methylamino-4-(N2,N2-dimethyl-hydrazino)-1,3-dimethyl-1,3,2lambda5,4lambda5-diazadiphosphetidine has been synthesized for the first time and a new way has been found for the synthesis of several compounds reported in literature.

  DOI：

  10.1007/bf00819518

文献信息

• Fluordiazadiphosphetidine, 11. Mitt.: Eine neue Methode zur Herstellung der doppelt zwitterionischen Verbindung (CH3N)6P4F8
  作者：Manfred Kubjacek、Kurt Utvary

  DOI：10.1007/bf00900000

  日期：1981.12
• Fluordiazadiphosphetidine, 16. Mitt.
  作者：Kurt Utvary、Manfred Kubjacek

  DOI：10.1007/bf00816522

  日期：1986.3
• Fluordiazadiphosphetidine, 10. Mitt.: Die Reaktion von 1,3-Dialkyl-2,2,2,4,4,4-hexaflouro-1,3,2?5,4?5-diazadiphosphetidine mitN-Trimethylsilylmethylamin
  作者：Manfred Kubjacek、Kurt Utvary

  DOI：10.1007/bf00900762

  日期：1981.3
• KUBJACEK, M.;UTVARY, K., MONATSH. CHEM., 1981, 112, N 12, 1353-1358
  作者：KUBJACEK, M.、UTVARY, K.

  DOI：——

  日期：——
• UTVARY, K.;KUBJACEK, M., MONATSH. CHEM., 1986, 117, N 3, 287-293
  作者：UTVARY, K.、KUBJACEK, M.

  DOI：——

  日期：——