1,1-bis(diethoxyphosphoryl)-N-(2,2-diphenylethenyl)methanimine | 1042684-32-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,1-bis(diethoxyphosphoryl)-N-(2,2-diphenylethenyl)methanimine
• CAS: 1042684-32-1
• 化学式: C₂₃H₃₁NO₆P₂
• 分子量: 479.45
• InChiKey: LFYPNCIHAUPNEW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  32
• 可旋转键数：
  13
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  83.4
• 氢给体数：
  0
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 1,1-bis(diethoxyphosphoryl)-N-(2,2-diphenylethenyl)methanimine 以 乙醚 为溶剂， 反应 15.0h， 以79%的产率得到diethyl [2-(diethoxyphosphoryl)-1-(2,2-diphenylvinyl)aziridin-2-yl]phosphonate
  参考文献：
  名称：

  Synthesis of N-vinyl 2,2-bisphosphonoaziridines from 1,1-bisphosphono-2-aza-1,3-dienes

  摘要：

  N-Vinyl 2,2-bisphosphonoaziridines are formed by treatment of 1,1-bisphosphono-2-aza-1,3-dienes with diazomethane. Depending on the substituents at the 4-position of the 1,1-bisphosphono-2-aza-1,3-dienes, exclusively 1-(ethenylamino)-2-phosphonoethenylphosphonates or mixtures of 1-(ethenylamino)-2-phosphonoethenylphosphonates and 2-imino-2-phosphonoethylphosphonates are obtained as side products. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.05.149
• 作为产物：
  描述：

  2-Chlor-2,2-diphenylacetaldehyd 、 (氨基亚甲基)双磷酸四乙酯 在 magnesium sulfate 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 4.5h， 以63%的产率得到1,1-bis(diethoxyphosphoryl)-N-(2,2-diphenylethenyl)methanimine
  参考文献：
  名称：

  Synthesis of 1,1-bisphosphono-2-aza-1,3-dienes, a new class of electron-deficient azadienes

  摘要：

  1,1-Bisphosphono-2-aza-1,3-dienes are formed by 1,4-dehydrohalogenation of the corresponding N-(bis-phosphonomethyl)-alpha-haloimines in moderate to good yields. The precursors could be formed by condensation of bisphosphono-amines and the corresponding alpha-haloaldehydes. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.05.031

文献信息

• Synthesis of 1,1-bisphosphono-2-aza-1,3-dienes, a new class of electron-deficient azadienes
  作者：Kurt G.R. Masschelein、Christian V. Stevens

  DOI：10.1016/j.tetlet.2008.05.031

  日期：2008.7

  1,1-Bisphosphono-2-aza-1,3-dienes are formed by 1,4-dehydrohalogenation of the corresponding N-(bis-phosphonomethyl)-alpha-haloimines in moderate to good yields. The precursors could be formed by condensation of bisphosphono-amines and the corresponding alpha-haloaldehydes. (C) 2008 Elsevier Ltd. All rights reserved.
• Synthesis of N-vinyl 2,2-bisphosphonoaziridines from 1,1-bisphosphono-2-aza-1,3-dienes
  作者：Pieter P.J. Mortier、Frederik E.A. Van Waes、Kurt G.R. Masschelein、Thomas S.A. Heugebaert、Christian V. Stevens

  DOI：10.1016/j.tetlet.2011.05.149

  日期：2011.8

  N-Vinyl 2,2-bisphosphonoaziridines are formed by treatment of 1,1-bisphosphono-2-aza-1,3-dienes with diazomethane. Depending on the substituents at the 4-position of the 1,1-bisphosphono-2-aza-1,3-dienes, exclusively 1-(ethenylamino)-2-phosphonoethenylphosphonates or mixtures of 1-(ethenylamino)-2-phosphonoethenylphosphonates and 2-imino-2-phosphonoethylphosphonates are obtained as side products. (C) 2011 Elsevier Ltd. All rights reserved.