1,5-di-(1-piperidyl)pentane | 24362-44-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 1,5-di-(1-piperidyl)pentane
• 英文别名: 1,5-dipiperidinopentane；N,N'-dipiperidylpentane；1,5-Dipiperidylpentane；1,1'-pentane-1,5-diyl-bis-piperidine；α,ε-Di-N-piperidinylpentan；N,N'-Pentamethylendipiperidin；1,5-Di(1-piperidinyl)pentane；1-(5-piperidin-1-ylpentyl)piperidine
• CAS: 24362-44-5
• 化学式: C₁₅H₃₀N₂
• 分子量: 238.417
• InChiKey: DKPQDGZBAKWOJD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  6.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,5-di-(1-piperidyl)pentane 、 碘甲烷 生成 1,1'-dimethyl-1,1'-pentanediyl-bis-piperidinium; diiodide
  参考文献：
  名称：

  v. Braun; Kuehn; Goll, Chemische Berichte, 1926, vol. 59, p. 2337

  摘要：

  DOI：
• 作为产物：
  描述：

  哌啶 在 钯 作用下， 反应 10.0h， 以96%的产率得到1,5-di-(1-piperidyl)pentane
  参考文献：
  名称：

  Catalytic alkyl group exchange reaction of primary and secondary amines

  摘要：

  DOI：

  10.1021/ja00353a025

文献信息

• Chemical conversions using sheet silicates: novel intermolecular elimination of ammonia from amines
  作者：James A. Ballantine、Howard Purnell、Mongkon Rayanakorn、John M. Thomas、Kevin J. Williams

  DOI：10.1039/c39810000009

  日期：——

  Ammonia is readily eliminated from molecular pairs of intercalated primary amines thereby generating the secondary amines in high yield in a novel proton mediated reaction; certain cyclic secondary amines produce unusual products by a similar interlamellar reaction.

  氨很容易从插入的伯胺分子对中消除，从而在新型的质子介导的反应中以高收率生成仲胺。某些环状仲胺通过类似的层间反应生成不寻常的产物。
• PROCESS FOR PREPARING FORMIC ACID
  申请人：Schneider Daniel

  公开号：US20130190532A1

  公开（公告）日：2013-07-25

  Process for obtaining formic acid by thermal separation of a stream comprising formic acid and a tertiary amine (I), in which a liquid stream comprising formic acid, tertiary amine (I) and water is produced by combining tertiary amine (I) and a formic acid source in the presence of water, water and organic decomposition products of the tertiary amine (I) are removed and formic acid is removed by distillation from the resulting liquid stream in a distillation apparatus, wherein the stream comprising water and organic decomposition products of the tertiary amine (I) which have been separated off is separated into two liquid phases, the upper liquid phase is removed and the lower, water-comprising liquid phase is recirculated to the formic acid source.

  通过热分离获得甲酸的过程，其中包括甲酸和三级胺（I）的流体，通过将三级胺（I）和甲酸源在水的存在下结合以产生包含甲酸、三级胺（I）和水的液体流，去除水和三级胺（I）的有机分解产物，并通过蒸馏从所得液体流中去除甲酸，在蒸馏设备中分离出含有水和三级胺（I）的有机分解产物的流体，将分离出的上层液相移除，下层含水液相循环回甲酸源。
• METHOD FOR PRODUCING AN AMINE
  申请人：Kubanek Petr

  公开号：US20090286977A1

  公开（公告）日：2009-11-19

  Processes comprising: (i) providing a reactant selected from the group consisting of primary alcohols, secondary alcohols, aldehydes, ketones and mixtures thereof; and (ii) reacting the reactant with hydrogen and a nitrogen compound selected from the group consisting of ammonia, primary amines, secondary amines and mixtures thereof, in the presence of a catalyst comprising a zirconium dioxide- and nickel-containing catalytically active composition, to form an amine; wherein the catalytically active composition, prior to reduction with hydrogen, comprises oxygen compounds of zirconium, copper, nickel and cobalt, and one or more oxygen compounds of one or more metals selected from the group consisting of Pb, Bi, Sn, Sb and In.

  包括以下步骤：(i) 提供从一次醇、二次醇、醛、酮及其混合物中选择的反应物；和(ii) 在存在包含氧化锆和镍的催化剂的催化活性组分的条件下，将反应物与氢气和从氨、一次胺、二次胺及其混合物中选择的氮化合物反应，生成胺；其中催化活性组分在与氢气还原之前，包括锆、铜、镍和钴的氧化物，以及从铅、铋、锡、锑和铟中选择的一个或多个金属的一个或多个氧化物。
• METHOD FOR THE PRODUCTION OF AN AMINE
  申请人：Kubanek Petr

  公开号：US20100274008A1

  公开（公告）日：2010-10-28

  Processes for preparing an amine, the processes comprising: reacting a reactant selected from the group consisting of primary alcohols, secondary alcohols, aldehydes, ketones, and mixtures thereof, with hydrogen and a nitrogen compound selected from the group consisting of ammonia, primary amines, secondary amines and mixtures thereof, in the presence of a zirconium dioxide-, copper- and nickel-containing catalyst; wherein the catalyst comprises a catalytically active composition which comprises, before reduction with hydrogen, oxygen compounds of zirconium, copper, and nickel, and 1.0 to 5.0% by weight of an oxygen compound of cobalt, calculated as CoO, and 0.2 to 5.0% by weight of a polyoxometalate.

  制备胺的方法，包括以下步骤：在含锆、铜和镍的催化剂存在下，将从原初醇、次级醇、醛、酮和其混合物中选择的反应物与氢气和从氨、原初胺、次级胺和其混合物中选择的氮化合物反应；其中，催化剂包括一个催化活性组分，该催化活性组分在氢气还原之前包括锆、铜和镍的氧化物化合物，以及1.0至5.0重量％的钴氧化物化合物（以CoO计算）和0.2至5.0重量％的多金属氧酸盐。
• CATALYST AND PROCESS FOR PREPARING AN AMINE
  申请人：Kubanek Petr

  公开号：US20110137030A1

  公开（公告）日：2011-06-09

  A process for preparing an amine by reacting a primary or secondary alcohol, aldehyde and/or ketone with hydrogen and a nitrogen compound selected from the group of ammonia and primary and secondary amines, in the presence of a supported copper-, nickel- and cobalt-containing catalyst, wherein the catalytically active material of the catalyst, before the reduction thereof with hydrogen, comprises oxygen compounds of aluminum, of copper, of nickel and of cobalt, and in the range from 0.2 to 5.0% by weight of oxygen compounds of tin, calculated as SnO, and catalysts as defined above.

  一种制备胺的方法，包括在铜、镍和钴载体催化剂的存在下，通过将一级或二级醇、醛和/或酮与氢气和氨或一级和二级胺中选择的一种氮化合物反应，制备胺。在还未经过氢气还原之前，催化剂的催化活性材料包括铝、铜、镍和钴的氧化物，以及在0.2%至5.0%的范围内，以SnO计算的锡氧化物。所述催化剂如上所定义。