[4-(2,4-dichloro-phenoxy)-phenyl]-acetic acid | 86308-92-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [4-(2,4-dichloro-phenoxy)-phenyl]-acetic acid
• 英文别名: [4-(2,4-Dichlor-phenoxy)-phenyl]-essigsaeure；4-(2,4-dichlorophenoxy)phenylacetic acid；4-(2,4-dichlorophenoxy)phenylacetate；2-(4-(2,4-Dichlorophenoxy)phenyl)acetic acid；2-[4-(2,4-dichlorophenoxy)phenyl]acetic acid
• CAS: 86308-92-1
• 化学式: C₁₄H₁₀Cl₂O₃
• 分子量: 297.138
• InChiKey: BATBTEWJDMJOAM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  对氯苯乙酸 以 sodium hydroxide 、 乙醚 为溶剂， 生成 [4-(2,4-dichloro-phenoxy)-phenyl]-acetic acid
  参考文献：
  名称：

  Process for the preparation of 2-(2,4-dichlorophenoxy)-phenylacetic acid

  摘要：

  2-(2,4-二氯苯氧基)苯乙酸制备工艺，其中2-氯苯乙酸和2,4-二氯苯酚的钾盐在提高温度的芳香烃溶剂中，在氯化铜催化剂的参与下反应，然后进行酸化处理。

  公开号：

  US04404396A1

文献信息

• Process for the preparation of 2-(2,4-dichlorophenoxy) phenylacetic acid
  申请人：RECKITT AND COLMAN PRODUCTS LIMITED

  公开号：EP0057047A1

  公开（公告）日：1982-08-04

  Process for the preparation of 2-(2,4-dichloro- phenoxy)phenylacetic acid in which the potassium salts of 2-chlorophenylacetic acid and 2,4-dichlorophenol are reacted in aromatic hydrocarbon solvents at elevated temperatures in the presence of a copper chloride catalyst, followed thereafter by acidification.

  制备 2-(2,4-二氯苯氧基)苯乙酸的工艺，其中 2-氯苯乙酸的钾盐和 2,4-二氯苯酚在芳香烃溶剂中，在氯化铜催化剂存在下，于高温下反应，然后酸化。
• Benzisoxazole derivatives
  申请人：ZENECA LIMITED

  公开号：EP0442655A2

  公开（公告）日：1991-08-21

  A herbicidal compound of formula (I) : in which Ar is an optionally subsitituted aryl or heterocyclic ring system; R1 and R2 are independently selected from H, optionally substituted alkyl, alkenyl or alkynyl, halogen, NRaRb, or R1 and R2 together with the carbon to which they are attached form an optionally substituted alkenyl or cycloalkyl group; R3 is C02R4, CN, COR4, CH20R4, CH(OH)R4, CH(OR4)RS, CH20S02R4, CH20S03R4, CH20NR6R7, CSNH2, COSR4, CSOR4, CONHSO2R4, CONR6R7, CONHNR6R7, CONHN+R6R7R8 Y-, CO2-M+ or COON=CR6R7; M is an agriculturally acceptable cation; Y- is an agriculturally acceptable anion; R4, and R5 are independently selected from H or an optionally substituted alkyl, aryl, alkenyl or alkynyl group; R6, R7, R8, R9, Ra and Rb are independently selected from H or an optionally substituted alkyl, alkenyl, aryl or alkynyl group or any two of R6, R7, R8, R9, Ra and Rb together with the atom to which they are attached form a cycloalkyl or heterocyclic ring: R6 and R7 may also be a heterocyclic ring; W is O or NR10 where R10 is H or lower alkyl; X is (CHz)n, CH=CH, CH(ORc)CH2, COCH2; where Rc is H or an optionally substituted alkyl, aryl, alkynyl or alkynyl group; and n is 0, 1 or 2. Process for the preparation of these compounds and compositions containing them are also described.

  式(I)的除草化合物： 其中 Ar 是任选取代的芳基或杂环环系； R1 和 R2 独立地选自 H、任选取代的烷基、烯基或炔基、卤素、NRaRb，或 R1 和 R2 与它们所连接的碳一起形成任选取代的烯基或环烷基； R3 是 C02R4、CN、COR4、CH20R4、CH(OH)R4、CH(OR4)RS、CH20S02R4、CH20S03R4、CH20NR6R7、CSNH2、COSR4、CSOR4、CONHSO2R4、CONR6R7、CONHNR6R7、CONHN+R6R7R8 Y-、CO2-M+ 或 COON=CR6R7； M 是农业上可接受的阳离子； Y- 是农业上可接受的阴离子； R4和R5独立地选自H或任选取代的烷基、芳基、烯基或炔基； R6、R7、R8、R9、Ra和Rb独立地选自H或任选取代的烷基、烯基、芳基或炔基，或 R6、R7、R8、R9、Ra和Rb中的任意两个与它们所连接的原子一起形成一个 环烷基或杂环： R6 和 R7 也可以是杂环； W 是 O 或 NR10，其中 R10 是 H 或低级烷基； X 是 (CHz)n、CH=CH、CH(ORc)CH2、COCH2； 其中 Rc 是 H 或任选取代的烷基、芳基、炔基或炔基；以及 n 是 0、1 或 2。 此外，还描述了这些化合物的制备过程以及含有这些化合物的组合物。
• US4404396A
  申请人：——

  公开号：US4404396A

  公开（公告）日：1983-09-13
• US5176737A
  申请人：——

  公开号：US5176737A

  公开（公告）日：1993-01-05
• Process for the preparation of 2-(2,4-dichlorophenoxy)-phenylacetic acid
  申请人：Reckitt & Colman Products Limited

  公开号：US04404396A1

  公开（公告）日：1983-09-13

  Process for the preparation of 2-(2,4-dichlorophenoxy)phenylacetic acid in which the potassium salts of 2-chlorophenylacetic acid and 2,4-dichlorophenol are reacted in aromatic hydrocarbon solvents at elevated temperatures in the presence of a copper chloride catalyst, followed thereafter by acidification.

  2-(2,4-二氯苯氧基)苯乙酸制备工艺，其中2-氯苯乙酸和2,4-二氯苯酚的钾盐在提高温度的芳香烃溶剂中，在氯化铜催化剂的参与下反应，然后进行酸化处理。