4-methyl-N-(2-(pyridin-2-yl)ethyl)benzamide | 253870-75-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-methyl-N-(2-(pyridin-2-yl)ethyl)benzamide
• 英文别名: 4-methyl-N-(2-pyridin-2-ylethyl)benzamide
• CAS: 253870-75-6
• 化学式: C₁₅H₁₆N₂O
• 分子量: 240.305
• InChiKey: MUNWABWUZRCOCY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  42
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,3,4,5,6-五氟苯胺 、 4-methyl-N-(2-(pyridin-2-yl)ethyl)benzamide 在 盐酸 、 五氯化磷 作用下， 以 乙醚 、 二氯甲烷 为溶剂， 反应 17.0h， 以73%的产率得到Moris-265 (Tatiana)
  参考文献：
  名称：

  Titanium Bis(amidinates) Bearing Electron Donating Pendant Arms as Catalysts for Stereospecific Polymerization of Propylene

  摘要：

  A series of titanium bis(amidinate) complexes containing pendant arms as one of the amidinate N substituents have been prepared and studied in the polymerization of propylene after their activation with MAO and other cocatalysts. The type of pendant arm greatly influences the reactivity and stereospecificity of the resulting polymers. The effect of the cocatalyst nature, its amount, and the time of the reaction have a dramatic effect on the reactivity of a titanium bis(amidinate) bis(dimethylamido) precatalyst containing a furyl group at the pendant arm.

  DOI：

  10.1021/om401165g
• 作为产物：
  描述：

  2-(2-氨乙基)吡啶 、 对甲基苯甲酰氯 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 生成 4-methyl-N-(2-(pyridin-2-yl)ethyl)benzamide
  参考文献：
  名称：

  Titanium Bis(amidinates) Bearing Electron Donating Pendant Arms as Catalysts for Stereospecific Polymerization of Propylene

  摘要：

  A series of titanium bis(amidinate) complexes containing pendant arms as one of the amidinate N substituents have been prepared and studied in the polymerization of propylene after their activation with MAO and other cocatalysts. The type of pendant arm greatly influences the reactivity and stereospecificity of the resulting polymers. The effect of the cocatalyst nature, its amount, and the time of the reaction have a dramatic effect on the reactivity of a titanium bis(amidinate) bis(dimethylamido) precatalyst containing a furyl group at the pendant arm.

  DOI：

  10.1021/om401165g

文献信息

• TRIAZOLOPYRIDINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF
  申请人：Genentech, Inc.

  公开号：US20160185780A1

  公开（公告）日：2016-06-30

  Compounds of Formula 0, Formula I and Formula II and methods of use as Janus kinase inhibitors are described herein.

  本文描述了化学式为0、化学式I和化学式II的化合物以及作为Janus激酶抑制剂的使用方法。
• Dihydropteridinones in the treatment of respiratory diseases
  申请人：Maier Udo

  公开号：US20070043055A1

  公开（公告）日：2007-02-22

  The present invention relates to the use of dihydropteridinones of formula 1 wherein the groups X, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 and R 7 have the meanings given in the claims and specification, for the preparation of a medicament for the treatment of respiratory diseases.
• Titanium Bis(amidinates) Bearing Electron Donating Pendant Arms as Catalysts for Stereospecific Polymerization of Propylene
  作者：Tatyana Elkin、Mark Botoshansky、Robert M. Waymouth、Moris S. Eisen

  DOI：10.1021/om401165g

  日期：2014.2.24

  A series of titanium bis(amidinate) complexes containing pendant arms as one of the amidinate N substituents have been prepared and studied in the polymerization of propylene after their activation with MAO and other cocatalysts. The type of pendant arm greatly influences the reactivity and stereospecificity of the resulting polymers. The effect of the cocatalyst nature, its amount, and the time of the reaction have a dramatic effect on the reactivity of a titanium bis(amidinate) bis(dimethylamido) precatalyst containing a furyl group at the pendant arm.