1,3-dihydro-2-benzothiophene-1-thione | 933-64-2

• 分子结构分类: 有机化合物 - 苯类化合物
• 英文名称: 1,3-dihydro-2-benzothiophene-1-thione
• 英文别名: 1,3-dihydroisobenzothiophene-1-thione；dithiophthalide；Dithiophthalid；3H-benzo[c]thiophene-1-thione；3H-Benzo[c]thiophen-1-thion；benzo[c]thiophene-1(3H)-thione；1,2-Dithiophthalide；3H-2-benzothiophene-1-thione
• CAS: 933-64-2
• 化学式: C₈H₆S₂
• 分子量: 166.268
• InChiKey: SUCYJIRIQQTBRB-UHFFFAOYSA-N

物化性质

• 沸点：
  289.5±43.0 °C(Predicted)
• 密度：
  1.35±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  57.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,3-dihydro-2-benzothiophene-1-thione 在 potassium hydrosulfide 作用下， 生成 3'H-[1,1']bi[benzo[c]thiophenylidene]-3-thione
  参考文献：
  名称：

  Gabriel; Leupold, Chemische Berichte, 1898, vol. 31, p. 2654

  摘要：

  DOI：
• 作为产物：
  描述：

  邻氰基氯苄 在 乙醇 作用下， 生成 1,3-dihydro-2-benzothiophene-1-thione
  参考文献：
  名称：

  Gabriel; Leupold, Chemische Berichte, 1898, vol. 31, p. 2646

  摘要：

  DOI：

文献信息

• Subnanomolar Precipitator of Thiophilic Metals
  申请人：Janda Kim D.

  公开号：US20080241943A1

  公开（公告）日：2008-10-02

  A fluorescent dye-doped crystalline assay is employed for selection and detection of thiophilic heavy metal ions. While comparable in analytical performance to known solution based methodologies, the formation of crystalline analytes provides for signal amplification, and consequently, a powerful platform whose analysis is directly amenable to high-throughput video capture systems. In a microcapillary format, this assay is capable of screening hundreds of samples per day for the presence of subnanomolar concentrations of Hg 2+ using a conventional fluorescence microscope.

  采用荧光染料掺杂结晶测定法选择和检测亲硫重金属离子。这种方法与已知的溶液基方法在分析性能上相当，但结晶分析物的形成提供了信号放大，因此，这是一个强大的平台，其分析可直接适用于高通量视频捕获系统。在微型毛细管格式下，该测定法能够使用传统荧光显微镜每天筛选数百个样品，以检测亚纳摩尔浓度的Hg2+的存在。
• Method for the preparation of a heterocyclic polymer
  申请人：DSM N.V.

  公开号：EP0707023A1

  公开（公告）日：1996-04-17

  The invention relates to a method for the preparation of a heterocyclic polymer from monomer units having a structure according to the formula of Fig. 1a or 1b, where R₁ and R₂ are the same or different and are selected from the group formed by hydrogen, alkyl groups with 1-20 carbon atoms, aryl groups with 6-20 carbon atoms, alkaryl groups with 7-40 carbon atoms, aralkyl groups with 7-40 carbon atoms, alkoxy groups with 1-18 carbon atoms, -O(CH₂CH₂O)nCH₃ with n = 4 and halogens; or where R₁ and R₂ both form part of a closed ring structure or from monomer units having a structure according to the formula of Fig. 3a or 3b, where R₁ to R₆ inclusive are the same or different and are selected from the group defined for R₁ and R₂; and with X = S and Y = S.

  1-18 个碳原子的烷氧基、-O(CH₂CH₂O)nCH₃（n = 4）和卤素；或 R₁ 和 R₂ 均构成闭环结构的一部分，或来自具有图 3a 或 3b 所示结构的单体单元。3a或3b，其中R₁至R₆（包括R₁和R₂）相同或不同，且选自为R₁和R₂定义的组；且X＝S和Y＝S。
• Accelerators for increasing the rate of formation of free radicals and reactive oxygen species
  申请人：Cavalier Discovery

  公开号：US20030082101A1

  公开（公告）日：2003-05-01

  The formation of free radicals is enhanced with photodynamic agents, sonodynamic agents, and systems and therapies utilizing ultrasound by subjecting the agent to light waves or sound waves in the presence of a metal, a reductant, or a chelate, or mixtures thereof.

  光动力药剂、声动力药剂以及利用超声波的系统和疗法，在有金属、还原剂或螯合物或它们的混合物存在的情况下，使药剂受到光波或声波的作用，可促进自由基的形成。
• Photoreactions of isoindoline-1-thiones with alkenes: unusual formation of tricyclic isoindolines
  作者：Takehiko Nishio、Norikazu Okuda

  DOI：10.1021/jo00040a049

  日期：1992.7

  Photochemical cycloaddition reactions of cyclic thioamides and alkenes have been examined. Irradiation of 2-arylisoindoline-1-thiones 1 in the presence of alkenes 2 gave the unexpected tricyclic isoindolines 3-18. The formation of tricyclic isoindolines can best be explained in terms of the intermediacy of aminospirothietane 27, formed by [2 + 2] photocycloaddition of the C=S double bond of 1 to the C=C double bond of 2. Ring cleavage of the resultant amino thietane, assisted by the participation of the nitrogen lone-pair electrons, produced zwitterions 28 and 29 or 1-mercaptoethylisoindole (30). Subsequent nucleophilic attack of the thiol anion on the iminium carbon of 29 or attack of the thiol group on C-3 of 30 gave the final products. Irradiation of isobenzofuran-1-thione (22) and isobenzothiophene-l-thione (23) in the presence of tetramethylethylene (2a) gave the corresponding spirothietanes 24 and 25.
• Nishio, Takehiko, Journal of the Chemical Society. Perkin transactions I, 1995, # 5, p. 561 - 568
  作者：Nishio, Takehiko

  DOI：——

  日期：——

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