N-[2-(6-phenylpyridin-2-yl)propan-2-yl]-2,6-di(propan-2-yl)aniline | 1058750-43-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: N-[2-(6-phenylpyridin-2-yl)propan-2-yl]-2,6-di(propan-2-yl)aniline
• CAS: 1058750-43-8
• 化学式: C₂₆H₃₂N₂
• 分子量: 372.553
• InChiKey: FDBRJTYHQLGWMM-UHFFFAOYSA-N

物化性质

• 沸点：
  492.5±45.0 °C(predicted)
• 密度：
  1.028±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.9
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  24.9
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  bis(tetrahydrofuran)tris(trimethylsilylmethyl)yttrium(III) 、 N-[2-(6-phenylpyridin-2-yl)propan-2-yl]-2,6-di(propan-2-yl)aniline 以 正己烷 为溶剂， 以87%的产率得到N2(Ph)Y(CH2SiMe3)(tetrahydrofuran)2
  参考文献：
  名称：

  烷基芳基和烷基苄基钇配合物中的选择性σ键易位。酰胺基吡啶配体支持的新的芳基和苄基氢化钇衍生物

  摘要：

  由6-芳基取代的酰氨基吡啶配体配位的二烷基钇复合物经历选择性的分子内sp 2或sp 3 CH键活化。用PhSiH 3处理所得的Y-C（烷基，芳基）或Y-C（烷基，苄基）体系时，σ-键易位反应选择性地发生在Y-C（烷基）键上，生成稀有的二聚芳基-氢或苄基-氢钇络合物。

  DOI：

  10.1021/om801044h
• 作为产物：
  描述：

  (2,6-diisopropyl-phenyl)-[1-(6-phen-1-yl-pyridin-2-yl)-ethylidene]-amine 、 三甲基铝 在 水 作用下， 以 甲苯 为溶剂， 以93%的产率得到N-[2-(6-phenylpyridin-2-yl)propan-2-yl]-2,6-di(propan-2-yl)aniline
  参考文献：
  名称：

  Yttrium‐Amidopyridinate Complexes: Synthesis and Characterization of Yttrium‐Alkyl and Yttrium‐Hydrido Derivatives

  摘要：

  AbstractAryl‐ or heteroaryl‐substituted aminopyridine ligands (N2HAr) react with an equimolar amount of [Y(CH2SiMe3)3(thf)2] to give yttrium(III)‐monoalkyl complexes. The process involves the deprotonation of N2HAr by a yttrium alkyl followed by a rapid and quantitative intramolecular sp2‐CH bond activation of the aryl or heteroaryl pyridine substituents. As a result, new Y complexes distinguished by rare examples of CH bond activations have been isolated and completely characterized. Selective σ‐bond metathesis reactions take place on the residual Y–alkyl bonds upon treatment with PhSiH3. Unusual binuclear metallacyclic yttrium(III)‐hydrido complexes have been obtained and characterized by NMR spectroscopy and X‐ray diffraction analysis.

  DOI：

  10.1002/ejic.200900934

文献信息

• WO2008/112133
  申请人：——

  公开号：——

  公开（公告）日：——
• Yttrium‐Amidopyridinate Complexes: Synthesis and Characterization of Yttrium‐Alkyl and Yttrium‐Hydrido Derivatives
  作者：Lapo Luconi、Dmitrii M. Lyubov、Claudio Bianchini、Andrea Rossin、Cristina Faggi、Georgii K. Fukin、Anton V. Cherkasov、Andrei S. Shavyrin、Alexander A. Trifonov、Giuliano Giambastiani

  DOI：10.1002/ejic.200900934

  日期：2010.2

  AbstractAryl‐ or heteroaryl‐substituted aminopyridine ligands (N2HAr) react with an equimolar amount of [Y(CH2SiMe3)3(thf)2] to give yttrium(III)‐monoalkyl complexes. The process involves the deprotonation of N2HAr by a yttrium alkyl followed by a rapid and quantitative intramolecular sp2‐CH bond activation of the aryl or heteroaryl pyridine substituents. As a result, new Y complexes distinguished by rare examples of CH bond activations have been isolated and completely characterized. Selective σ‐bond metathesis reactions take place on the residual Y–alkyl bonds upon treatment with PhSiH3. Unusual binuclear metallacyclic yttrium(III)‐hydrido complexes have been obtained and characterized by NMR spectroscopy and X‐ray diffraction analysis.
• Selective σ-Bond Metathesis in Alkyl−Aryl and Alkyl−Benzyl Yttrium Complexes. New Aryl− and Benzyl−Hydrido Yttrium Derivatives Supported by Amidopyridinate Ligands
  作者：D. M. Lyubov、G. K. Fukin、A. V. Cherkasov、Andrei S. Shavyrin、A. A. Trifonov、L. Luconi、C. Bianchini、A. Meli、G. Giambastiani

  DOI：10.1021/om801044h

  日期：2009.2.23

  Yttrium dialkyl complexes coordinated by 6-aryl-substituted amidopyridinate ligands undergo selective intramolecular sp2 or sp3 C−H bond activation. Upon treatment with PhSiH3 of the resulting Y−C(alkyl, aryl) or Y−C(alkyl,benzyl) systems, a σ-bond metathesis reaction takes place selectively at the Y−C(alkyl) bond, generating rare dimeric aryl−hydrido or benzyl−hydrido yttrium complexes, respectively

  由6-芳基取代的酰氨基吡啶配体配位的二烷基钇复合物经历选择性的分子内sp 2或sp 3 CH键活化。用PhSiH 3处理所得的Y-C（烷基，芳基）或Y-C（烷基，苄基）体系时，σ-键易位反应选择性地发生在Y-C（烷基）键上，生成稀有的二聚芳基-氢或苄基-氢钇络合物。