5-methyl-N-(5-methylhexyl)hexan-1-amine | 1262679-19-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 5-methyl-N-(5-methylhexyl)hexan-1-amine
• CAS: 1262679-19-5
• 化学式: C₁₄H₃₁N
• 分子量: 213.407
• InChiKey: DEMHQFSACGENNJ-UHFFFAOYSA-N

物化性质

• 沸点：
  256.9±8.0 °C(Predicted)
• 密度：
  0.792±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5
• 重原子数：
  15
• 可旋转键数：
  10
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  5-methyl-N-(5-methylhexyl)hexan-1-amine 、 氯羰基亚磺酰氯 在 氯 作用下， 以 二氯甲烷 为溶剂， 以88.2%的产率得到bis-(5-methyl-hexyl)-carbamoyl chloride
  参考文献：
  名称：

  N,N-二取代氨基甲酰卤及其衍生物的改进的一锅法合成

  摘要：

  报道了使用氯羰基亚磺酰氯作为羰基化剂制备 N,N-二取代氨基甲酰氯的方便的一锅法。它包括仲胺与氯代羰基亚磺酰氯在非质子有机溶剂存在下反应生成相应的 N,N-二取代氨基甲酰卤。在不使用光气的情况下插入羰基是该方法的新颖之处。Resume ´ : On a developmentpeune methode monotope pour preparer des chlorures de carbamoyle N,N-dissubstitues qui fait appel au chlorure de chlorocarbonylsulfenyle comme agent de carbonylation。Elle implique la 反应 d'amines secondaires avec le chlorure de chlorocarbonylsulfenyle en 存在 d'un 溶剂有机

  DOI：

  10.1139/v10-138

文献信息

• ABUSE DETERRENT AND ANTI-DOSE DUMPING PHARMACEUTICAL SALTS USEFUL FOR THE TREATMENT OF ATTENTION DEFICIT/HYPERACTIVITY DISORDER
  申请人：King Clifford Riley

  公开号：US20120028960A1

  公开（公告）日：2012-02-02

  A pharmaceutical composition comprising a drug substance consisting essentially of a pharmaceutically acceptable organic acid addition salt of an amine containing pharmaceutically active compound wherein the amine containing pharmaceutical active compound is selected from the group consisting of racemic or single isomer ritalinic acid or phenethylamine derivatives and the drug substance has a physical form selected from amorphous and polymorphic.

  一种药物组合物，包括基本上由含有药用活性化合物的胺的药用可接受的有机酸加合盐组成的药物物质，其中含有药用活性化合物的胺被选择自光学异构体或单异构体利他林酸或苯乙胺衍生物的群体，并且该药物物质具有从无定形到多型的物理形式。
• PHOTOBASE GENERATOR
  申请人：Kuramoto Ayako

  公开号：US20110233048A1

  公开（公告）日：2011-09-29

  There is intended to provide the novel compounds which generate a base easily when irradiated with long wavelength light (active energy rays), a photobase generator containing the compounds and a photobase generation method, and the present invention relates to the compounds represented by the general formula [1], a photobase generator containing the compounds and a photobase generation method: (wherein, Ar represents any of groups with specific structures selected from the group consisting of an anthracenyl group, an anthraquinonyl group and a pyrenyl group; R 1 and R 2 each independently represent a hydrogen atom or a linear, branched or cyclic alkyl group having 1 to 10 carbon atoms, or represent ones which can form an alicyclic ring containing nitrogen atom(s) or an aromatic ring containing nitrogen atom(s) together with a nitrogen atom to which they are bound, which the rings having 3 to 8 carbon atoms which may have a substituent, R 3 and R 4 each independently represent a hydrogen atom, a linear, branched or acyclic alkyl group having 1 to 10 carbon atoms).

  本发明旨在提供当受长波长光（活性能量射线）照射时易于产生碱的新化合物，包含这些化合物的光碱发生器以及光碱生成方法，本发明涉及由通式[1]表示的化合物，包含这些化合物的光碱发生器以及光碱生成方法：（其中，Ar代表从蒽基团、蒽醌基团和芘基团中选择的具有特定结构的任何基团；R1和R2各自独立地代表氢原子或具有1至10个碳原子的直链、支链或环烷基基团，或表示能够与它们结合的氮原子形成含氮原子的脂环烷基环或含氮原子的芳香环，这些环具有3至8个碳原子，可能有取代基；R3和R4各自独立地代表氢原子，具有1至10个碳原子的直链、支链或非环烷基基团）。
• STILBENE-BASED COMPOUND OR SALT THEREOF, AND POLARIZING FILM, POLARIZING PLATE, AND DISPLAY DEVICE
  申请人：NIPPON KAYAKU KABUSHIKI KAISHA

  公开号：US20200157353A1

  公开（公告）日：2020-05-21

  The present disclosure is a stilbene-based compound or a salt thereof represented by a following formula (1), wherein a group X represents a nitro group or an amino group optionally having a substituent; a group Y represents an amide group optionally having a substituent or a naphthotriazole group optionally having a substituent; and p and q each independently represent an integer of 0 to 2.

  本公开涉及一种基于stilbene的化合物或其盐，其表示如下式（1），其中X代表一个硝基或一个氨基，可选地具有取代基；Y代表一个酰胺基，可选地具有取代基，或一个萘三唑基，可选地具有取代基；p和q各自独立地代表0到2的整数。
• Abuse-Deterrent Methadone for the Safe Treatment of Drug Abuse and Pain Relief
  申请人：Pisgah National Laboratories, Inc.

  公开号：US20130338229A1

  公开（公告）日：2013-12-19

  Provided is a drug substance and a method of treating an ailment comprising administering an oral dose of a drug product comprising the drug substance wherein the drug substance comprises an organic acid addition salt of methadone. The organic acid addition salt is selected from the group consisting of pamoate and xinafoate wherein the drug substance is bioavailable under gastrointestinal administration but is not bioavailable under administration at a mucosal membrane other than gastrointestinal or release from a depot injectable product.

  本文提供了一种药物物质和治疗方法，包括给予一种药物产品的口服剂量，该药物产品包括所述药物物质，其中所述药物物质包括美沙酮的有机酸加成盐。所述有机酸加成盐选自沙酸盐和西那福酸盐的群体，其中所述药物物质在胃肠道给药下具有生物利用度，但在黏膜膜以外的其他部位给药或从释放出的深层注射产品中不具有生物利用度。
• Method for the cultivation of normal diploid cells and cultivation medium used therefor
  申请人：Asahi Kasei Kogyo Kabushiki Kaisha

  公开号：EP0082974A2

  公开（公告）日：1983-07-06

  A method for the multiplication of normal diploid cells from animals is described, comprising cultivating the cells in a culture medium containing an amine derivative or derivatives represented by the general formula: NR1R2R3 (wherein R1, R2 and R3 represents a straigh, branched or cyclic alkyl group or a hydrogen atom, provided that R1, R2 and R3 are not hydrogen atoms at the same time. Addition of these specific amine derivatives permits multiplication of normal diploid cells in a culture medium containing no serum or only a limited concentration of serum. These amine derivatives are inexpensive and can be stored for a long period of time, and their storage and handling are easy. The use of these amine derivatives overcomes various problems encountered in using serum in the multiplication of normal diploid cells according to conventional methods.

  本发明描述了一种用于繁殖动物正常二倍体细胞的方法，该方法包括在含有胺衍生物或由通式表示的衍生物的培养基中培养细胞：NR1R2R3（其中 R1、R2 和 R3 代表直链、支链或环状烷基或氢原子，但 R1、R2 和 R3 不能同时为氢原子）。添加这些特定的胺衍生物可以使正常的二倍体细胞在不含血清或仅含有限浓度血清的培养基中繁殖。这些胺衍生物价格低廉，可长期保存，而且易于储存和处理。这些胺衍生物的使用克服了按照传统方法使用血清繁殖正常二倍体细胞时遇到的各种问题。